1/3. Candida sepsis in pregnancy and the postpartum period.Colonization of the vagina by Candida is common during pregnancy, while candida sepsis in pregnancy is rare. A case of candida sepsis complicating an abortion prompted us to review seven additional cases that occurred during pregnancy or the postpartum period. In four women candidemia developed during pregnancy or following abortion, while in the other four it developed postpartum. Seven women had an apparent predisposing factor, such as antibiotic treatment or an intrauterine device. The clinical course was difficult in four patients and ended in death in three instances. Both amphotericin b and 5-fluorocytosine proved effective for treatment.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
2/3. Placental and fetal candidiasis. Presentation of a case of an abortus.The authors present a case of intrauterine fetal infection by candida, in an abortion of four months, associated with an I.U.D. In the placenta and adnexa we observed an acute inflammation consisting of extraplacental membranitis, omphalitis, chorio-amnionitis and choriovasculitis with a marked villitis and intervillitis. In the fetus, involvement of the skin, lungs and pharynx was observed. This case represents, probably the 15th reported instance of congenital fetal candidiasis, and the first case of a candida hematogenic placental infection acquired from the fetal blood. The fetus undoubtedly acquired its infection by an ascending route, through the contamined amniotic fluid.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
3/3. fluconazole in candida albicans sepsis during pregnancy: case report and review of the literature.Candida sepsis during pregnancy is a rare but life-threatening complication of infection with candida albicans. In contrast to the situation with other antimicrobial agents, there exists only limited experience with systemic antifungal therapy during pregnancy. A recent report focuses on amphotericin b treatment in systemic fungal infection during pregnancy. The present report discusses a pregnant patient with candida albicans sepsis and endophthalmitis as well as candida infection of the oral and genital mucous membranes, after hyperalimentation and broad spectrum antibiotic therapy via a central venous catheter. The patient was treated with 10 mg/kg fluconazole from week 16 of gestation for a total duration of 50 days. Adverse effects did not occur and the rest of the pregnancy proceeded favourably for both the mother and the baby.- - - - - - - - - - ranking = 0.5keywords = candida (Clic here for more details about this article) |