1/4. adoptive transfer of vitiligo after allogeneic bone marrow transplantation for non-Hodgkin's lymphoma.vitiligo developed in a 50-year-old man 9 months after allogeneic transplantation from his HLA-identical sister who had had this disease for several years. Our findings suggest adoptive transfer of vitiligo by haematopoietic stem cell transplantation, and lend support to the autoimmune nature of this disease.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
2/4. tinea versicolor: a light and electron microscopic study of hyperpigmented skin.hyperpigmentation in lesions of tinea versicolor has previously been reported to be a result of the effects of the fungus Pityrosporon orbiculare on melanosome formation and distribution. Examination of biopsy specimens from lesions of hyperpigmented tinea versicolor involving vitiliginous skin reveals an absence of melanosomes and melanocytes. Reddish-tan and fawn-colored hyperpigmentation in tinea versicolor of this type is not due to melanin pigment. The possible nature of the pigmentation that delineates hyperpigmented tinea versicolor from normal skin is discussed.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
3/4. vitiligo associated with BCG-methanol extraction residue in malignant melanoma. Report of a case.A pronounced vitiliginous reaction developed at the sites of MER/BCG injections given as an adjuvant immunotherapy to a patient with malignant melanoma. To our knowledge, this is the third report on patients exhibiting vitiligo apparently induced by immunotherapy and the first in association with MER. This association may be a sign for an antimelanocytic effect and may offer a further confirmation for the autoimmune nature of vitiligo.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
4/4. An unusual cause of burn injury: unsupervised use of drugs that contain psoralens.Although psoralens are useful components of the psoralen ultraviolet A-range therapy that is mainly used for the treatment of vitiligo, psoriasis, and hypopigmented scars, they have a narrow margin of safety. Oral and topical forms of psoralen-containing drugs are routinely used in medicine. Because psoralens sensitize skin to ultraviolet A light, phototoxic reactions are the most frequent adverse effect of this treatment. sunburn may sometimes be a major injury in psoralen users because high doses or inappropriate use of the drug may render the skin extremely sensitive. In this article, we present the case of a vitiligo patient who was admitted to our facility with an intense burn after the topical use of 8-methoxypsoralen solution as a suntanning agent. We will also discuss the unusual nature of this type of burn and the course of phototoxic lesions and their differences from a typical sunburn.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |