1/34. Giant juvenile xanthogranuloma of the tongue.Juvenile xanthogranulomas (JXGs) are rare, benign, fibrohistiocytic lesions. They usually appear as one or more cutaneous papules on the head, neck, or trunk in infants. Twelve cases of oral JXGs have been reported, four of which involved the tongue. We present a 6-year-old girl with a large tongue mass diagnosed as JXG after an excisional biopsy. Histological and immunohistochemical staining results are presented. This is the first reported case of a giant oral JXG. A review of the literature on these unusual lesions is presented, along with discussion of their differential diagnosis and key aspects of the patient's evaluation, management, and pathological diagnosis.- - - - - - - - - - ranking = 1keywords = granuloma (Clic here for more details about this article) |
2/34. A case of sarcoidosis involving the tongue.sarcoidosis is a systemic granulomatous disorder which commonly affects the skin. Involvement of the tongue is rare; a review of the previous literature over the last 30 years revealed only six cases of sarcoidosis affecting the tongue. We studied a case of sarcoidosis involving the tongue in a 32-year-old Japanese woman with characteristic clinical and pathological findings. She visited our department with a complaint of a tongue lesion of which she had been aware for a month. A diagnosis of sarcoidosis was made for the lesion by clinical and pathological examinations. Oral involvement by sarcoidosis is rare, however this disorder should be considered as a possible cause of intraoral granulomatous lesions.- - - - - - - - - - ranking = 0.4keywords = granuloma (Clic here for more details about this article) |
3/34. Pyogenic granuloma of the tongue early after allogeneic bone marrow transplantation for multiple myeloma.Oral complications occur frequently after bone marrow transplantation (BMT). Some of them are caused by regimen-related toxicity of the preparative regimen, and others by infections. In addition, oral tissues are targets of graft-versus-host disease (GVHD). Oral granulomatous lesions are not a common complication after BMT, and are especially rare on the tongue. Such rare lesions reported in the literature, developed late after BMT with oral chronic GVHD. We present here a patient who developed pyogenic granuloma of the tongue early after allogeneic BMT done for multiple myeloma. Regimen-related mucositis, oral acute GVHD, the administration of cyclosporine A, and the preexisting macroglossia might be responsible for the formation of granuloma.- - - - - - - - - - ranking = 1.4keywords = granuloma (Clic here for more details about this article) |
4/34. Oral manifestation of tertiary syphilis: case report.This paper describes a case of benign tertiary syphilis represented by a solitary hypertrophic lesion on the dorsum surface of the tongue. The diagnosis was confirmed by serologic tests (VDRL and FTA-ABS). Histopathological analysis of biopsy specimens revealed, in the lamina propria, the presence of well-developed granulomas associated with necrotic areas (gummatous lesion). Currently, tertiary syphilis is rarely seen; however, this case emphasizes that it still exists and must be considered in the differential diagnosis of inflammatory oral lesions.- - - - - - - - - - ranking = 0.2keywords = granuloma (Clic here for more details about this article) |
5/34. mucocele of the anterior lingual salivary glands (glands of Blandin and Nuhn): report of 5 cases.The anterior lingual salivary glands (glands of Blandin and Nuhn) are mixed mucous and serous glands that are embedded within the musculature of the anterior tongue ventrum. Five cases of mucocele of the glands of Blandin and Nuhn are presented. These mucoceles on the anterior tongue ventrum were exophytic and resembled pyogenic granulomata, polyps, or squamous papillomata. In 2 cases, the onset of the mucocele was associated with trauma to the anterior tongue. All cases were mucus extravasation phenomena. A history of trauma and recovery of mucus with fine needle aspiration are helpful in the clinical diagnosis of mucocele of the glands of Blandin and Nuhn, as are the following characteristics of the mucocele: rapid onset, increase and reduction in size, bluish color, and fluid-filled consistency. During surgery, the glands that are deep in the tongue musculature are commonly left behind, resulting in persistence of the lesion. Careful clinical evaluation of these lesions and preoperative awareness of the surgical anatomy of the glands of Blandin and Nuhn may minimize the need for repeated surgical procedures.- - - - - - - - - - ranking = 0.2keywords = granuloma (Clic here for more details about this article) |
6/34. Pyogenic granuloma (lobular capillary hemangioma) of the tongue.A patient with a pyogenic granuloma which occurred in an unusual location and at an earlier age is presented. Pyogenic granuloma is not an uncommon entity which may occur on oral mucosa, face and fingers. The most frequent location encountered for oral cavity pyogenic granuloma is the gingiva and the tongue is a rare location for its occurrence. These lesions are usually seen between 11 and 40 years age. Surgical excision and removal of etiological factors are needed for treatment.- - - - - - - - - - ranking = 1.4keywords = granuloma (Clic here for more details about this article) |
7/34. Lingual granuloma gravidarum.granuloma gravidarum or pregnancy tumor is a benign lesion of the gingival mucosa which occurs during pregnancy. It is a pyogenic granuloma. This case report presents the clinical, histopathological features and the treatment of a granuloma gravidarum in a Sudanese patient in the puerperium.- - - - - - - - - - ranking = 1.2keywords = granuloma (Clic here for more details about this article) |
8/34. Treatment of Miescher's cheilitis granulomatosa in melkersson-rosenthal syndrome.cheilitis granulomatosa is the most frequent dermatological sign in the melkersson-rosenthal syndrome. We reviewed 27 cases of this syndrome diagnosed and treated in the last 20 years. All the patients were surgically treated and received intralesional corticosteroids during surgery and tetracycline hydrochloride (500 mg, twice daily) after the operation to prevent recurrence.- - - - - - - - - - ranking = 1keywords = granuloma (Clic here for more details about this article) |
9/34. malacoplakia of the tongue. A case report and review of the literature.Our aim is to present a singular case of malacoplakia of the tongue and a review of the literature. malacoplakia (from the Greek "malacos", soft, and "placos", plaque) is a granulomatosis initially described in 1902. It has the clinical aspect of a yellow-brown, soft plaque of variable size, characterized by a central navel or ulcer and an intense peripheral hyperaemia, usually located in the urogenital and gastrointestinal tract. The mortality rate is higher than 50% if vital organs are involved. In the world literature there are 16 cases of the head and neck region and particularly only 2 of them are located on the tongue. In these 2 cases the lesion caused some distress to the patients who referred to a medical observation for this motive. Conversely we report a case of asymptomatic lingual malacoplakia occurring in a 57-year-old woman, diagnosed by chance during a stomatological examination in the Department of oral medicine and Periodontology of Turin University. In this case the outcome was quite plain and our patient did not need any supporting medical therapy. Nevertheless the potential danger of malacoplakia should underline the importance of a more careful histological assessment of submucosal nodules of the oro-pharyngeal region. Moreover the histopathological characteristic, the present etiopathogenetic hypothesis and the therapeutic pattern of malacoplakia suggested in the literature are discussed.- - - - - - - - - - ranking = 0.2keywords = granuloma (Clic here for more details about this article) |
10/34. Quadhelix appliance therapy resulting in pyogenic granuloma of the tongue.This paper describes the examination, diagnosis and treatment of a rapidly enlarging tongue mass presenting in a healthy 12-year-old girl. This mass caused distress to both the patient and her parents and diagnostic uncertainty for her general medical and dental practitioners. The lesion was in fact caused by an orthodontic quadhelix appliance and responded to simple treatment.- - - - - - - - - - ranking = 0.8keywords = granuloma (Clic here for more details about this article) |
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