Cases reported "Thrombosis"

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1/82. Homozygous prothrombin gene mutation and ischemic cerebrovascular disease: a case report.

    We report the case of a 31-year-old woman who, at the age of 26 suffered from an episode of superficial thrombophlebitis in the left leg, experienced two episodes of transient ischemic attacks at the age of 30 and had an ischemic stroke with left-sided hemiparesis at the age of 31 years. A cerebral CT scan showed an ischemic lesion in the right sylvian area involving the opercular and nucleocapsular regions. Her father had had an ischemic stroke at the age of 54 years and died at the age of 58; her mother had had a myocardial infarction at the age of 48 years and died at 51 years from breast cancer. Laboratory investigation of the patient demonstrated high levels of fibrinogen, F II, F VII, F 1 2, FPA and ACA-IgG with low levels of HDL cholesterol associated with homozygosity for the 20210 A genotype. There were no other genetic or acquired prothrombotic defects. In conclusion, this case strongly suggests a clinically significant role ot the prothrombin gene mutation in both arterial and venous thrombosis.
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keywords = thrombophlebitis
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2/82. Anaerobic septicaemia by fusobacterium necrophorum: Lemierre's syndrome.

    Lemierre's syndrome is characterized by acute pharyngotonsillitis with secondary thrombophlebitis of the internal jugular vein which is complicated by multiple metastatic foci of infections. This syndrome is caused by fusobacterium necrophorum in healthy young persons and is extremely rare in occurrence. A pre-school child with Lemierre's syndrome is reported. The diagnostic and therapeutic aspects are emphasized in order to sensitize physicians to this uncommon condition.
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keywords = thrombophlebitis
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3/82. Central vein thrombophlebitis associated with a permanent silastic central catheter.

    The use of silastic catheters for total parenteral nutrition has greatly expanded. Their decided advantages of flexibility and minimal thrombogenicity favor their use in the long-term nutritional support. This case report details the development of central vein thrombophlebitis associated with an indwelling central silastic catheter. This uncommon hazard of central venous catheterization is not eliminated by the use of silastic catheters.
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ranking = 5
keywords = thrombophlebitis
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4/82. Free-floating thrombus in the femoral vein--a challenge in phlebologic diagnostics.

    Although thrombophlebitis may be a complication of an incompetent great saphenous vein, it usually has a benign outcome. The risk of embolisation is present especially when ascending progression of superficial venous thrombosis extends to the femoral vein. The proximal extension of the thrombus often precedes clinically visible symptoms. Use of colour duplex sonography is superior to phlebography in assessing the saphenofemoral junction area and thrombus propagation in these cases. Our case report details the difficulties encountered in the diagnosis and therapy of a patient with a free-floating thrombus at the saphenofemoral junction.
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keywords = thrombophlebitis
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5/82. Traumatic lymphangitis of penis.

    The appearance of a firm, nodular, cord-like structure in the coronal sulcus of the penis has heretofore been considered and reported in the urologic literature as thrombophlebitis of the superficial veins. Further study and review of the literature reveal this condition to be a traumatic lymphangitis which is directly related to sexual trauma and runs a short, asymptomatic, self-limited course.
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keywords = thrombophlebitis
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6/82. Mesenteric inflammatory veno-occlusive disease: a rare cause of intestinal ischemia. The first description of recurrent disease.

    BACKGROUND: Mesenteric inflammatory veno-occlusive disease (MIVOD) is a rare cause of intestinal ischemia of unknown etiology. Histologically, MIVOD is characterized by extended thrombophlebitis and fibrous organized thrombosis of multiple veins. The arteries are by definition not involved. Management includes surgery in all cases described. recurrence has not been described until now. methods: We describe the case of a 64-year-old woman operated with the suspicion of intestinal ischemia. Clinical and histopathological characteristics are reported. RESULTS: The patient underwent a right hemicolectomy and segmental resection of the terminal ileum 15 months later for a recurrence. The histological examination of the resected specimen confirmed the diagnosis of MIVOD and a recurrence thereof. CONCLUSION: MIVOD is a rare cause of colonic ischemia. recurrence of the disease, which is described here for the first time, is unusual after surgical resection.
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ranking = 1
keywords = thrombophlebitis
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7/82. Serious consequences of a sore throat.

    Lemierre's syndrome, caused by fusobacterium necrophorum, is a potentially fatal sequelae of a sore throat characterised by septicaemia, internal jugular vein thrombophlebitis and metastatic abscesses. The Chief Medical Officer reported in February 2001 that the incidence is increasing. Two cases seen in one year, with different presentations, are reported. The first patient presented with sepsis, jaundice, hepatic abscesses and portal vein/superior mesenteric vein thrombosis, whilst the second presented with sepsis, sore throat and internal jugular vein thrombophlebitis. Both patients were treated with antibiotics and anticoagulants with a favourable outcome.
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ranking = 2
keywords = thrombophlebitis
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8/82. Central venous thrombophlebitis diagnosed by computerized tomography scanning.

    A case is described in which computerized tomography scanning aided in a prompt diagnosis and assessment of an intravenous catheter-induced septic thrombus. Computerized tomography scanning detected gas bubbles within the thrombus, which extended from the right subclavian vein into the superior vena cava, and retrograde propagation of the thrombus into the right internal jugular vein. Computerized tomography scanning also helped in the assessment of the amount of deep tissue swelling present and the competence of the upper respiratory tract.
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ranking = 4
keywords = thrombophlebitis
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9/82. Management of thrombophlebitis in the prepartum period. A case report.

    The case of a 30-year-old female who presented with acute onset of ileofemoral thrombophlebitis during the 37th week of pregnancy is presented. Treatment with intravenous infusion of heparin was initiated on the day of admission. The following day, the patient went into active labor. heparin was stopped, and a Greenfield filter was placed in the suprarenal inferior vena cava. Six hours later, the patient had a normal vaginal delivery. Fifteen hours after delivery, heparin was restarted. The patient was discharged eight days later on therapeutic levels of Coumadin. Anticoagulation was maintained for six months and at one year she was asymptomatic.
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ranking = 5
keywords = thrombophlebitis
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10/82. Laparoscopic procedures as a risk factor of deep venous thrombosis, superficial ascending thrombophlebitis and pulmonary embolism--case report and review of the literature.

    Since its introduction laparoscopic surgery has been used for many indications, e.g., cholecystolithiasis, hernia, appendicitis, fundoplication, benign large bowel disease and gynaecological disorders. It has been considered as safe and efficient procedure for most patients with only few contraindications, mostly heart-lung disease. When the initial enthusiasm has been replaced by a more critical observation, more complications of laparoscopy or laparoscopic surgery were not only discovered but also reported. In laparoscopic hernia repair there is a tendency for severe complications when compared to open surgery. There is a controversy on possible side-effects of laparoscopic surgery, e.g., thrombosis, and the increased necessity of prophylaxis for thromboembolic events. Recently a growing number of reports on thromboembolic complications in association with laparoscopic surgery were published. Thrombosis may be caused by detrimental effects of pneumoperitoneum on venous flow (increased abdominal pressure and negative Trendelenburg position) and activation of the haemostatic system. Further risk factors may contribute to the risk to develop venous thrombosis. It is well accepted that varicose veins are associated with an increased risk for the thrombosis. However, the association of varicose veins with complications of laparoscopic surgery is unclear. The possible impact of thrombotic complications makes an analysis of the association of varicose veins or a history of deep vein thrombosis on the development of thrombosis after laparoscopic surgery mandatory. Although this is the first report on ascending thrombophlebitis and thrombosis of the sapheno-femoral junction after laparoscopic surgery, the incidence of deep vein thrombosis or superficial thrombophlebitis after laparoscopic surgery or laparoscopy may be much higher according to the pathophysiological changes during and after these procedures. In many patients venous thrombosis may not be recognized or it appears when the patient is already discharged. CONCLUSION: laparoscopy and laparoscopic procedures may have an increased risk for the development of thrombosis due to increased abdominal pressure and negative Trendelenburg position. patients with varicose veins and a history of thromboembolism may aggravate laparoscopy associated risks for the development of thromboembolic complications. Superficial thrombophlebitis in the thigh is not a benign disease entity and may lead to deep vein thrombosis (DVT) and pulmonary embolism (PE). Urgent surgical treatment (high ligation) may be warranted together with low-molecular weight heparin (LMWH) and compressions therapy. patients with varicose veins and a history of venous thrombosis may not be suitable candidates for laparoscopic surgery. family practitioners may be confronted with this complication more often since patients are discharged earlier from hospital after laparoscopic interventions due to legislative regulations.
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ranking = 7
keywords = thrombophlebitis
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