1/18. Septic candidasis with intrahepatic cholestasis and immunoglobuline deficiency after renal transplantation.Two renal allograft recipients with acquired immunoglobulin deficiency had a disseminated infection with candida albicans. Septic fever, intrahepatic cholestasis and pulmonary mycotic disease were the prominent clinical symptoms. recurrence of septic fever during the clinical course was associated with increase of intrahepatic cholestasis. On the other hand there was an amelioration of cholestasis when effective antimycotic therapy was instituted. In our patients there was no evidence that intrahepatic cholestasis was drug-related. It was assumed that toxic metabolits of candida albicans were responsible for intrahepatic cholestasis.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
2/18. Candida sepsis following transcervical chorionic villi sampling.BACKGROUND: The use of invasive devices and broad spectrum antibiotics has increased the rate of candidal superinfections. Candida sepsis associated with pregnancy is rare. Candida sepsis following chorionic villi sampling (CVS) has never been reported. CASE: A 31 -year-old pregnant woman presented with signs of sepsis one day after undergoing transcervical CVS. blood culture and curettage material yielded C. albicans. She was treated with 400 mg of fluconazole daily for 4 weeks and completely recovered. CONCLUSION: Candida sepsis should be considered in the differential diagnosis of sepsis following CVS.- - - - - - - - - - ranking = 0.16666666666667keywords = candida (Clic here for more details about this article) |
3/18. Candida endocarditis in neonates: report of five cases and review of the literature.Candidal endocarditis is an uncommon and serious complication of invasive Candida infection in neonates. The aim of this study was to further characterise candidal endocarditis in neonates. Between 1995 and 2000, 56 patients were diagnosed with Candida bloodstream infections (CBSI) in the Neonatal intensive care Unit of Schneider Children's Medical Center of israel. Five of them (9%) developed mycetoma of the right atrium. None of the patients had congenital heart disease or a central venous catheter in the right heart at the time of diagnosis. All were treated with amphotericin b alone or in combination with other antifungals, without surgical intervention. One patient died of the disease and one died later of polymicrobial sepsis and necrotizing enterocolitis. A review of the literature since 1980 yielded an additional 25 cases of candidal endocarditis. For the whole sample (n = 30) survival rate was 73.1%. Six of the 10 patients treated with antifungal agents and surgery survived (60%), compared with 13 of the 20 patients treated only medically (65%) (P = 1.0). Candida endocarditis in neonates differs from fungal endocarditis in adults in risk factors, clinical presentation and outcome. As the outcome of surgical and medical treatment are comparable, antifungal therapy alone may be a valid therapeutic option in high-risk cases.- - - - - - - - - - ranking = 0.33333333333333keywords = candida (Clic here for more details about this article) |
4/18. Beware! Fungal urosepsis may follow endoscopic intervention for prolonged indwelling ureteral stent.We present a 38-year-old lady with a prolonged indwelling ureteral stent that had been placed for pain relief after development of Steinstrasse following extracorporeal lithotripsy for a 2.5-cm left renal calculus. The patient developed candidal urosepsis within 6 hours after ureteroscopy and percutaneous nephrolithotomy (PCNL) for the removal of residual fragments. She subsequently recovered on systemic antifungal therapy in the form of intravenous amphotericin B and achieved complete stone clearance after repeat ureteroscopy and PCNL. Fungal urosepsis is known to complicate the postoperative course in chronically debilitated patients with poor nutritional status or those with diabetes or other significant comorbities. To our knowledge, this is the first reported case of a patient with no significant comorbities developing fungal urosepsis after endoscopic intervention for a long-term indwelling ureteral stent.- - - - - - - - - - ranking = 0.16666666666667keywords = candida (Clic here for more details about this article) |
5/18. Diagnostic value of serum antibody to candida in an extensively burned patient.This report gives details of an extensively burned patient who died of candidiasis. Retrospectively, by using the procedure of indirect immunoperoxidase staining, we measured the levels of antibody to candida in the stored patient's serum, collected from the time of admission to our hospital until death. Gradual increases in the antibody titres to candida were seen over the postburn period. The findings can be useful in diagnosing candidiasis.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
6/18. Polyfungal systemic infections in pediatric oncology patients.Three cases of two fungal agents causing simultaneous systemic infection in immunocompromised pediatric patients are presented and the literature is reviewed. All three patients had several underlying factors that predispose to systemic fungal infections. A species of candida was identified initially as an etiologic agent in all of the three patients causing subcutaneous abscesses, urinary tract infections, fungemia, catheter exit site infection, or pneumonia. However, a few days later blood cultures grew aspergillus species in two of the three patients; in the third patient aspergillus was identified on microscopic examination of the spleen. All three patients had an associated bacteremia with either staphylococcus aureus or S. epidermidis requiring vancomycin therapy. Presence of aspergillus infection required treatment with amphotericin. Difficulties in making a definitive diagnosis of systemic fungal disease may explain paucity of reports in the literature with simultaneous polyfungal systemic infection.- - - - - - - - - - ranking = 0.16666666666667keywords = candida (Clic here for more details about this article) |
7/18. Extracorporeal shock wave lithotripsy of a kidney stone complicated with Candida albicans septicaemia and endophthalmitis. Case report.Following a routine extracorporeal shock wave lithotripsy of a kidney stone, candida septicaemia and eight days later candida endophthalmitis developed.- - - - - - - - - - ranking = 0.33333333333333keywords = candida (Clic here for more details about this article) |
8/18. candida albicans shunt infection.Seven cases of successfully treated candida albicans cerebrospinal fluid shunt infections are reported. Treatment consisted of shunt removal and intravenous amphotericin b in all cases and intraventricular amphotericin b in 4 cases. Serious underlying medical illness, recent antibiotic therapy, indwelling intravascular and/or Foley catheters, coincident candidiasis and low birth weight prematurity are major risk factors for candida shunt infection. Candida shunt infection appears to occur by either contamination at the time of shunt placement or by hematogenous dissemination.- - - - - - - - - - ranking = 0.16666666666667keywords = candida (Clic here for more details about this article) |
9/18. Hansenula anomala: a new fungal pathogen. Two case reports and a review of the literature.Fungal infections are characteristic of severely immunocompromised patients. Noncandidal yeasts represent a growing proportion of such infections. risk factors for developing fungal infections include the use and abuse of central venous catheters. Two patients with gynecologic malignant neoplasms became fungemic with Hansenula anomala, a yeast of the Ascomycetes class, after insertion of central venous catheters. Frequent catheter manipulation and prolonged use favored the development of fungemia in both patients. A review of the literature revealed 19 additional cases over the course of four decades, all in hosts with underlying diseases. Thirteen of these cases have been described in the last 18 months, suggesting either increased recognition or increased frequency of infection with this organism. All tested isolates have been susceptible to amphotericin b. patients have generally responded to catheter withdrawal and amphotericin b administration. Hansenula anomala is an opportunistic pathogen, whose clinical behavior resembles that of Candida species.- - - - - - - - - - ranking = 0.16666666666667keywords = candida (Clic here for more details about this article) |
10/18. streptococcus bovis bacteraemia associated with candidal lesions of the large bowel in a leukaemic child. A case report.A 5-year-old boy with acute myeloblastic leukaemia had large-bowel masses, demonstrated at autopsy, 5 weeks after an episode of streptococcus bovis bacteraemia. The association of Strept. bovis bacteraemia with large-bowel disease, well documented in adults, should be considered in children.- - - - - - - - - - ranking = 0.66666666666667keywords = candida (Clic here for more details about this article) |
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