Cases reported "Schistosomiasis"

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1/15. schistosomiasis of spinal cord and skin.

    We record the simultaneous occurrence of cutaneous and spinal cord lesions of schistosomiasis and speculate upon the mode of this distant spread.
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2/15. schistosomiasis (bilharziasis) mansoni of the spinal cord stimulating an intramedullary tumor.

    A case of involvement of the spinal cord by schistosoma masoni is described. There was a granuloma in the conus medullaris stimulating an intramedullary tumor. biopsy led to the correct diagnosis. After decompression of the spinal cord and the oral administration of niridazole (Ambilhar) the patient recovered satisfactorily.
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3/15. schistosomiasis. paraplegia and ectopic skin lesions as admission symptoms.

    A 33-year-old man, who had been a teacher in africa from 1966 to 1969, was hospitalizaed in December 1973 for radiculomyelitis with progressive paraplegia and analgesia of the lower limbs. On his fourth day in the hospital, a pruritic, papular dermatitis appeared on both lower thoracic paraspinal areas. Microscopical examination of biopsy specimens of skin from those areas showed schistosome ova within many palisading granulomas in the dermis. The morphological features of the skin lesions, as seen by gross and microscopical examination, and the morphological and staining characteristics and the pathophysiology of the schostosome organism will be discussed. The longevity of the adult worm in the portal circulation is particularly important; a long interval may elapse between the time the patient leaves the area where he became infected and the time of appearance of the lesions.
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4/15. schistosomiasis of the spinal cord presenting as progressive myelopathy. Case report.

    The authors report on a case of schistosomiasis of the spinal cord in an individual returning to ireland after a 25-year residence in africa, where the infection affects approximately 200 million people.
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5/15. schistosomiasis of the spinal cord.

    Four cases of spinal cord schistosomiasis were characterized by paraparesis, sensory loss, and sphincter disturbances progressing over hours to days. One patient showed deterioration over months and remission after laminectomy, followed by the typical, rapidly progressive deficits. Biopsies on two patients showed granulomatous and necrotizing myelitis. Spontaneous improvement and unremitting deterioration, despite chemotherapy, make evaluation of treatment difficult. A survey of all previously reported cases provided no consistent pattern of response to any treatment modalities. laminectomy for decompression and diagnosis, administration of antischistosomal medications, and high-dose oral prednisone early in the illness are recommended.
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6/15. spinal cord schistosomiasis. A clinical, laboratory and radiological study, with a note on therapeutic aspects.

    Fourteen patients with schistosomiasis of the spinal cord are described. They fall into two groups: 7 patients had clinical and computer-assisted myelographic evidence of lesions in the conus medullaris or cauda equina, or both. The clinical picture in the remaining 7 patients was usually that of acute or subacute transverse myelitis with normal or equivocal CT myelographic appearances. Granulomas containing bilharzial ova were found in 2 female patients with conus swelling subjected to laminectomy and biopsy. In 1 of these the ova were identified as S. haematobium while in the second, unidentified bilharzial ova were found. A presumptive diagnosis of spinal cord schistosomiasis was made in the remaining 12 patients based on characteristic clinical and investigative profiles. All 13 patients tested showed evidence of bilharzial infection based on positive blood serology or the detection of bilharzial ova, or both. All but 1 patient showed at least one of the following abnormalities on CSF examination: pleocytosis, an elevated protein content and as indicated by the presence of oligoclonal IgG bands, an elevated IgG index and an increased CSF IgG synthesis rate. A CSF bilharzia enzyme-linked immunosorbent assay (ELISA) test, developed to indicate the presence of schistosomal infection within the theca, was found to be sensitive although not entirely specific for the diagnosis of spinal cord schistosomiasis. Eleven of the 14 patients showed rapid clinical improvement, 8 after praziquantel and corticosteroid treatment, 2 after operation and 1 spontaneously. Significant reductions in the CSF cell count, protein concentration and bilharzia ELISA titre, and in intrathecal antibody production, occurred following praziquantel and corticosteroid therapy. The CSF sugar level showed a significant rise. A reduction in conus size was observed in 3 patients when CT myelography was repeated after medical therapy. The normalization of most of the laboratory parameters after combined medical treatment with praziquantel and corticosteroids, together with clinical and radiological improvement, strengthened the presumptive diagnosis of cord schistosomiasis and supports the policy of early intensive medical treatment (as opposed to surgical therapy) for this condition when diagnosed on indirect evidence.
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7/15. paraplegia from schistosomiasis.

    paraplegia, a rare complication of schistosomiasis has been reported in the literature. However, a detailed description of neurological recovery and long-term functional follow-up has not been published. In the cases presented, one patient experienced slow recovery over several years and remains nonambulatory. The other patient, infected at the same time and place, has completely recovered neurologically. Recovery was independent of the rehabilitation efforts applied. case reports, discussion of spinal cord injury due to schistosomiasis and recommendations for treatment are presented in detail.
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8/15. schistosomiasis of the spinal cord in a Yemeni boy. A report of a case with brief review of literature.

    A 13-year old Yemeni boy who presented with flaccid paraplegia was thought to have a spinal cord tumor on myelography. Microscopic examination of surgically excised material revealed bilharzial granulomas. Brief review of relevant literature on schistosomiasis of the spinal cord, with particular reference to the middle east, is presented.
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9/15. schistosomiasis in ectopic or unusual sites. A report of 5 cases.

    schistosomiasis usually affects the urinary tract or the bowel; 5 cases occurring in an endemic area in which the disease presented in an unusual site--lung, ovary, testis, intestine and spinal cord--are described.
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10/15. Massive spinal cord necrosis in schistosomiasis.

    spinal cord lesions are rare in schistosomiasis. Schistosomal ova usually elicit a granulomatous myelitis in which necrotic foci are sometimes observed, but necrotic foci are sometimes observed, but extensive cord necrosis is exceptional. A 19-year-old Brazilian woman had transverse myelitis that ended fatally one month and a half thereafter. autopsy disclosed a total myelonecrosis below T-4, and ova at schistosoma mansoni were demonstrated in the necrotic cord tissue and leptomeniges. This is, to our knowledge, the most extensive necrosis of the spinal cord reported to date in schistosomiasis.
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