1/27. Cerebral radionecrosis following the treatment of parotid tumours: a case report and review of the literature.radiotherapy is an accepted part of the treatment of malignant tumours of the parotid gland. The use of radiotherapy in benign parotid tumours, where spillage of tumour cells has occurred at operation, is more controversial. radiotherapy to the parotid bed is not without morbidity. Complications may arise as a result of radiation damage to neighbouring structures and there is also potential to induce malignant disease. A patient, whose postoperative radiotherapy following resection of a pleomorphic salivary gland adenoma was complicated by cerebral necrosis, is discussed. The literature pertaining to morbidity of radiotherapy for parotid tumours is reviewed.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/27. dental caries after radiotherapy of the oral regions.Five cases of dental caries after radiation therapy of the oral regions for treatment of carcinomas are presented. The differences in clinical appearance and behavior between radiation caries and ordinary smooth-surface dental caries are described. The role of salivary gland irradiation and the resultant xerostomia in the development of these lesions is discussed. Some explanations are offered as to how these lesions develop in the light of current knowledge concerning plaque and the development of dental caries. Several measures that may be taken to reduce the incidence and severity of these lesions are suggested.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
3/27. Successful pregnancy by intracytoplasmic sperm injection after radiotherapy-induced azoospermia.A 27-year-old male, who underwent excision and radiotherapy for a pineal gland germinoma four years previously, subsequently developed panhypopituitarism and, thus, complete azoospermia. Gonadotrophin replacement therapy resulted in the production of a small number of motile spermatozoa which were used for Intracytoplasmic Sperm Injection (ICSI) into oocytes obtained from his wife. After successful fertilization and embryo transfer, a singleton intrauterine pregnancy was achieved which resulted in the normal delivery of a morphologically normal male live infant at term.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
4/27. Dramatic parotid uptake of I-131 on a diagnostic whole-body scan.radiation sialadenitis is a complication of I-131 therapy for thyroid cancer. They authors report a case of intense uptake by parotid glands in a diagnostic I-131 scan (2 mCi) in whom sialadenitis had developed previously after a 100-mCi dose of I-131. Similar examples of images could not be found in the literature.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
5/27. Parotid nodular fasciitis in a mobile phone user.We describe the first case of nodular fasciitis affecting the deep lobe of the parotid gland in a 39-year-old male telephone engineer and its possible association with the high usage of mobile phones.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
6/27. Tracer accumulation in radiation necrosis of the brain after thallium-201 SPECT and [11C]methionine PET--case report.A 69-year-old woman was treated by local irradiation for a malignant lymphoma of the left parotid gland. Three years after the radiation therapy, magnetic resonance imaging revealed heterogeneously enhanced masses in the left temporal lobe and left cerebellum. thallium-201 chloride single photon emission computed tomography (Tl-SPECT) revealed high uptake and [11C]methionine positron emission tomography (Met-PET) revealed moderate uptake in both masses. Stereotactic biopsy was performed. The histological diagnosis was radiation necrosis. She was treated with steroids. Neurosurgeons should be aware of the difficulty in differentiating tumor recurrence from radiation necrosis even with Tl-SPECT and Met-PET, and the importance of obtaining a histological diagnosis for radiation necrosis.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
7/27. Ocular neuromyotonia: a case report.Ocular neuromyotonia is a rare motility disorder occurring after tumor irradiation near the skull base or as a consequence of vascular abnormalities. Ocular myasthenia, convergence spasm and a cyclic third nerve palsy must be considered as differential diagnoses. The case of a 32-year-old woman suffering from intermittent diplopia six months after radiation therapy of a recurrent pituary gland adenoma is presented.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
8/27. Postirradiation necrosis of the temporal lobe presenting as a glioma. Case report.A patient is reported who presented with manifestations of a space-occupying lesion in the left temporal lobe thought to be a metastasis, but on radiological examination and surgical exploration appeared to be a diffuse infiltrative glioma. Some 21 months earlier he had received a course of fast neutron therapy to a carcinoma of the left parotid gland. diagnosis by microscopic examination revealed changes characteristic of delayed radiation necrosis.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
9/27. Feasibility of intensity-modulated radiation therapy in the treatment of advanced cervical chordoma.AIMS AND BACKGROUND: Postoperative radiation is often given in cases of cervical chordoma because of the high incidence of local recurrence. The tumor mass usually surrounds the spinal cord and infiltrates vertebral bone. A combined technique using protons or electrons to boost the initial photon fields is generally applied. We evaluated the use of dynamic intensity-modulated radiation therapy as an alternative technique for treating advanced cervical chordoma. methods AND STUDY DESIGN: A female patient with incomplete resection of a vertebral chordoma surrounding C2-C3 was irradiated with a total dose of 58 Gy (ICRU point) in 2 Gy daily fractions for 29 days between December 2001 and January 2002. Beam arrangement consisted of seven 6 MV non-opposed coplanar fields. Pretreatment quality assurance included checking of the absolute dose at reference points and 2D dose map analysis. Treatment was delivered with a 120-leaf collimator in sliding window mode. To verify the daily setup, portal images at 0 degrees and 90 degrees were compared with the simulation images before treatment delivery (manual matching) and after treatment delivery (automatic anatomy matching). RESULTS AND CONCLUSIONS: The mean dose to the planning target volume (PTV) was 57.6 /- 2.1 Gy covering 95% of the PTV per 95% isodose. The minimum dose to the PTV (D99) was 53.6 Gy in the overlapping area between the PTV and the spinal cord planning organ at risk volume (PRV). The maximum dose to the spinal cord was 42.2 Gy and to the spinal cord PRV (8 mm margin) 53.7 Gy. The mean dose to the parotid glands was 37.4 Gy (homolateral gland) and 19.5 Gy (contralateral gland). Average deviation in setup was -1.1 /- 2.5 mm (anterior-posterior), 2.4 /- 1.3 mm (latero-lateral), 0.7 /- 0.9 mm (craniocaudal) and -0.43 /- 1 degree (rotation). CONCLUSIONS: In the treatment of chordomas surrounding the spinal cord, intensity-modulated radiotherapy can provide high dose homogeneity and PTV coverage. Frequent digital portal image-based setup control is able to reduce random positioning errors for head and neck cancer patients immobilized with conventional thermoplastic masks.- - - - - - - - - - ranking = 1.5keywords = gland (Clic here for more details about this article) |
10/27. Intensity-modulated radiation therapy: not a dry eye in the house.Inverse planned intensity-modulated radiation therapy (IMRT) has been applied to patients in a conformal fashion in order to avoid the lacrimal gland. In the present study, we report a patient in which a potential planned dose of 63 Gy to the lacrimal gland for a conventional plan was reduced to 12 Gy to the lacrimal gland for the IMRT plan. Dose objective inverse planning was provided using a Pinnacle treatment planning computer and treatment was delivered using a Varian dynamic multileaf collimator (MLC) on a Varian linear accelerator. Because multiple MLC segments are used to deliver the modulated treatment, conventional dose checks by manual calculation are not practical. To aid in an alternative dosimetric verification process, the Pinnacle planning computer has two unique dose tools, which provide axial and beams eye view doses on user-specified check phantoms. The combined field axial dose tool matched our ion chamber dose checks within /- 2.4% at the isocentre. The individual beams eye view dose tool matched film dose maps within /- 3% in the umbra.- - - - - - - - - - ranking = 1.5keywords = gland (Clic here for more details about this article) |
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