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1/4. anemia as a sign of abdominal pregnancy.

    Advanced abdominal pregnancy is an ominous occurrence. The diagnosis is usually made when the physician considers this possibility as the answer to a puzzling obstetric problem. Marked, unexplained anemia, associated with unusual second- and third-trimester signs and symptoms, should warn the physician of the possibility of a near-term abdominal pregnancy.
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2/4. Peripartum complications. hemorrhage, embolism, hypertension, and infection.

    Maternal peripartum complications continue to be a significant problem in the united states, even among previously healthy women. The problems include peripartum bleeding, infection, hypertension, and thromboembolic disease. Primary care physicians are often called upon to treat these conditions. An awareness of the approach to diagnosis and management helps to ensure optimal outcome.
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3/4. Efficient diagnosis of thrombocytopenia.

    thrombocytopenia may be a benign, incidental finding in an asymptomatic patient or the sign of a potentially life-threatening disorder. The history, physical examination and peripheral blood smear can assist the physician in determining the diagnosis and treatment. After the initial blood count is repeated to help eliminate the possibility of laboratory error, a thorough history, complete physical examination, complete blood cell count and appropriate laboratory tests are required. The history may reveal related illnesses, risk factors such as infection or drug use, or a family history suggestive of congenital thrombocytopenia. The physical examination should concentrate on the lymphatic and hepatosplenic systems, with the physician looking for jaundice, fever or petechiae. With the review of a complete blood cell count and a peripheral smear examination, the initial work-up is completed and may prevent additional, unnecessary testing. Etiology-specific tests follow if needed. Serious spontaneous bleeding is usually a risk only in patients with platelet levels under 20,000 per mm3.
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4/4. Essential thrombocythemia during pregnancy.

    Essential thrombocythemia is a myeloproliferative disorder characterized by a persistent increase in the platelet count. The disease occurs more often in late middle age, but reports confirm the possibility of earlier occurrence. When the disease affects women during pregnancy, an adverse pregnancy outcome is possible: abortion, intrauterine fetal death, abruptio placentae, intrauterine growth retardation, and premature delivery. The possibility of thrombosis formation in this disease encouraged many physicians to use various treatments aimed at lowering the platelet count. Treatments used during pregnancy include acetylsalicylic acid, dipyridamole, heparin, and plateletpheresis. This article describes pregnancy outcomes and reviews the suggested treatments.
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