1/28. Metastatic neuroblastoma of the mandible mimicking osteogenic sarcoma radiologically. Case report.This paper presents a case of a neuroblastoma of the adrenal gland metastasizing to the mandible of a 21-month-old infant, which presented radiographically as the so-called 'sun-ray' appearance, characteristic of osteogenic sarcoma.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/28. osteosarcoma of the thyroid gland.A case of osteosarcoma of the thyroid gland in a 61-yr-old woman who died from tracheal compression due to local recurrence 6 wk after operation is presented. The main features of 27 previously reported similar cases, and the problems of histogenesis are discussed.- - - - - - - - - - ranking = 5keywords = gland (Clic here for more details about this article) |
3/28. Multimodality management of a case of primary osteogenic sarcoma of the zygoma.Craniofacial osteogenic sarcomas are rare primary malignant bone tumors and very few cases involving zygomatic bone were reported in literature. We present our experience of multimodality management of a case of primary osteogenic sarcoma of zygoma. Wide radical excision of the tumor including the parotid gland was done followed by three cycles of adjuvant chemotherapy and fifty Gy of external radiotherapy. The patient is disease-free at two years follow-up. Till 1970s, craniofacial osteogenic sarcomas were managed mainly by radical surgery with a high local failure rate. With the advances made in the field of radiotherapy and chemotherapy, multimodality therapy is playing a major role in the treatment of these aggressive tumors with better overall and disease-free survival.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
4/28. Treatment of solid tumors following allogeneic bone marrow transplantation.Second solid tumors are well known late complications after bone marrow transplantation. Treatment strategies are ill defined. We retrospectively evaluated treatment and outcome in a single institution. From August 1974 to July 1996, six solid tumors were observed in five of 387 patients 2 to 13 years after BMT, corresponding to a probability of developing a second solid tumor of 9% (1-17%, 95 CI) at 15 years: these comprised endometrial carcinoma, carcinoma of the thyroid gland, cervical carcinoma, sarcoma of the small intestine, osteosarcoma of the tibia and ovarian carcinoma. All five patients were treated as intensively as they would be without a history of BMT. At last follow-up four of the five patients were alive and without signs of tumor. We postulate that second solid tumors after BMT should be treated as de novo tumors. Early detection based on consequent clinical follow-up of the transplant patients might explain the relatively good outcome.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
5/28. osteosarcoma as a second malignancy after treatment for neuroblastoma.A 4-month old girl was diagnosed as having stage IV neuroblastoma of the right adrenal gland. Preoperative chemotherapy was given, followed by local surgical excision. Postoperatively, irradiation of the tumor bed and adjuvant chemotherapy was given for 11 months. Nine years after cessation of chemotherapy, the patient developed left hip-joint pain. biopsy of the ischium showed chondroblastic osteosarcoma. limb salvage surgery was performed after preoperative chemotherapy. Postoperatively, adjuvant chemotherapy was given for 14 months. Twenty-two months after treatment for the secondary osteosarcoma, the patient has been remained in disease-free condition without any evidence of relapse. A second osteosarcoma occurring outside the radiation field after treatment for neuroblastoma is quite rare. This unusual case emphasized the need for close monitoring for development of second malignant neoplasms in survivors of neuroblastoma even in the absence of a known predisposing factor, such as radiation therapy.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
6/28. Adrenal gland metastasis in osteogenic osteosarcoma. A radiological case report.Adrenal gland metastases from osteogenic sarcoma are rare and an unusual pattern of relapse. The recognition of solitary metastases, particularly when located in uncommon sites is very important for subsequent treatment. The authors describe the radiological features of an adrenal metastases from osteogenic sarcoma.- - - - - - - - - - ranking = 5keywords = gland (Clic here for more details about this article) |
7/28. Dura resection in combination with en bloc spondylectomy for primary malignant tumors of the spine.STUDY DESIGN: Resection of a primary malignant tumor of the bone with wide surgical margins has become the golden standard in oncological surgery. In the case of a spinal tumor with tumor invasion of the spinal canal, a wide resection could necessitate resection and subsequent replacement of part of the dura. SUMMARY OF BACKGROUND DATA: Dura replacement is a consequent surgical step in the treatment of primary malignant tumors of the spine. methods: We present the case of a 27-year-old male with a tumor of the dorsal elements of D6. After paraplegic symptoms, a laminectomy of D5 to D7 was performed and histologic examination revealed the presence of an osteosarcoma. After neoadjuvant polychemotherapy, a wide resection of the dorsal elements from D4 to D7 combined with a resection of the dorsal part of the dura was planned. Replacement of the dura was performed with Lyodura (B. Braun Melsungen AG, Melsungen, germany). The spine was stabilized with an ISOLA instrumentation (Depuy International Ltd., Leeds, england). For wound closure, a pedicled latissimus dorsi flap and split skin graft were necessary. In a second step, ventral spondylodesis with texas Scottish Rite Hospital instrumentation (Sofamor Danek, Memphis, TN) was performed. RESULTS: One hundred sixteen months after surgery the patient is alive without evidence of disease, is pain free, and has returned to his profession and life without any restrictions.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
8/28. carcinosarcoma of the submandibular salivary gland. Immunohistochemical findings.Carcinosarcomas of the salivary glands are rare lesions that generally have been associated with benign mixed tumors. The authors report a case of a submandibular gland lesion, which occurred in a 64-year-old man, that was composed of intermingled ductal type adenocarcinoma and osteogenic sarcoma with a large component of osteoclast-like giant cells. The local recurrence of the tumor was entirely sarcomatous with no epithelial component observed. There was no histologic evidence of a preexisting or coexisting pleomorphic adenoma. Immunohistochemical studies confirmed two separate populations of tumor cells, corresponding to the histologic growth pattern. The authors review the literature and discuss histogenetic implications of distinction between de novo carcinosarcoma and carcinosarcoma in association with pleomorphic adenoma.- - - - - - - - - - ranking = 6keywords = gland (Clic here for more details about this article) |
9/28. Primary osteosarcoma of the thyroid gland.Primary extraosseous osteosarcoma of the thyroid gland is a rare tumor which is associated with a poor prognosis. In this report, we discuss such a tumor and its recurrence in a 78-yr-old female with multinodular goiter, focusing on the imaging evaluation of this unusual tumor.- - - - - - - - - - ranking = 5keywords = gland (Clic here for more details about this article) |
10/28. Multifocal osteosarcoma with extensive pleural metastatic disease.An eighteen year old female presented with multifocal synchronous osteosarcoma, with multiple skeletal foci of tumour in long bones, pelvis and spine. The radiographically dominant lesion was in the right ilium, and this was considered to be the primary site. There was an extensive osseous pleural plaque and there were also metastases to lungs, peritoneum, abdominal wall, adrenal gland and lymph nodes. A review of the literature reveals that multifocal osteosarcoma is an uncommon condition and is probably due to metastatic disease and not multiple primary lesions. Pleural metastatic disease in osteosarcoma has been seldom reported.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
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