1/33. Radiographic manifestation of clear cell odontogenic tumor.Clear cell odontogenic tumors are uncommon, only 20 cases having been reported in the literature. We report a case that presented with unique radiographic manifestations over a period of 12 years; no similar case has been reported to date. documentation of the malignant nature of the condition and of the range of clinical and radiographic manifestations with which this neoplasm can present provides useful insight into its pathogenesis and progression. Early and timely recognition of the lesion, histopathologic examination, and aggressive interventional procedures are in order to successfully treat this condition and prevent a potentially fatal outcome.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
2/33. The amyloid deposit in calcifying epithelial odontogenic tumor is immunoreactive for cytokeratins.Calcifying epithelial odontogenic tumor, also known as Pindborg tumor, is a rare benign tumor with locally aggressive behavior. It is characterized by squamous epithelial cells, calcifications, and eosinophilic deposits that have been identified as amyloid. We report a case of calcifying epithelial odontogenic tumor and investigate the nature of the amyloid, using histologic, immunohistochemical, and ultrastructural studies. The amyloid was immunohistochemically negative for basement membrane components and positive for all cytokeratin stains performed (cocktail of cytokeratins 1, 5, 6, 8, 13, and 16, and cytokeratins AE1 and AE3). The amyloid stained focally in a glandular-like pattern, reminiscent of the epithelial glandlike structures of the tumor. We conclude that the amyloid is derived from filamentous degeneration of keratin filaments that originate from the tumor squamous epithelium. The keratin degeneration is part of a developmental or aging process that the tumor undergoes.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
3/33. Calcifying epithelial odontogenic (Pindborg) tumor with malignant transformation and metastatic spread.BACKGROUND: Pindborg tumors (calcifying epithelial odontogenic tumors) are uncommon neoplasms of odontogenic origin most often located in the posterior mandible. First described in detail in 1955 by Pindborg, these tumors are considered benign but can be locally aggressive in nature, with recurrence rates of 10% to 15% reported. The malignant form of this tumor is exceedingly rare. methods: We describe the case of a 64-year-old woman initially treated for a painful infected left mandibular third molar. The patient underwent extraction of the tooth and excision of an associated soft tissue component. Subsequent histologic review identified a Pindborg tumor of the left posterior mandible. RESULTS: After initial excision, this tumor recurred twice, with the recurrences exhibiting a progression to a malignant Pindborg tumor (odontogenic carcinoma) with vascular invasion and spread to a cervical lymph node. Further treatment involved radical surgery and adjuvant radiotherapy. At last review 12 months after treatment, the patient was disease free. CONCLUSIONS: This article describes only the second case of odontogenic carcinoma. The transformation from benign to malignant histologic findings has not previously been documented in this tumor. The salient clinical features of this case are presented along with supportive pathologic and radiologic evidence.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
4/33. myxoma of the jaws. Report of three cases.Odontogenic myxoma is a locally aggressive, uncommon benign tumour which arises from mesenchymal tissues normally present in developing teeth. The most frequent locations of odontogenic myxoma are the posterior regions of the mandible, as well as the condylar region. Since odontogenic myxomas are not associated with any specific clinical or radiological sign, a histopathological examination of the specimen is required for confirmation of the primary diagnosis. We report three cases of myxoma diagnosed during the last 18 years. Two of them were located in atypical regions of the mandible and one was located in the maxilla. Presence of a slow-growing swelling associated with expansion of the bone plates raised suspicion of a tumour in two cases, while in the third patient the myxoma was an incidental finding during radiological examination. Due to the unspecific nature of these lesions, in every case a histopathological examination of the surgical specimen was required for diagnostic confirmation. In one of the three reported cases, we shall underline the need to follow a correct diagnostic work-up of all radiolucent lesions of the jaws, in order to avoid contraindicated therapeutic procedures.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
5/33. Cementoblastoma associated with a primary tooth: a rare pediatric lesion.An intraosseous, slightly painful swelling was noted upon clinical examination of an eight-year-old girl. The swelling was of an unspecified duration and slow growing in nature. A radiopaque mass with a radiolucent periphery attached to the roots of the mandibular right second primary molar was noted on a periapical radiograph. The diagnosis of cementoblastoma was verified by the histologic assessment.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
6/33. Central odontogenic fibroma-like tumors, hypodontia, and enamel dysplasia: review of the literature and report of a case.A patient with multiple odontogenic fibroma-like tumors in the mandible and enamel dysplasia is presented, bringing the total number of cases reported in the literature to 3. In addition to these manifestations, this case had hypodontia. The absence of associated teeth, the size of the lesions, the lingual expansion, and the green-yellow polarization of collagen with Picrosirius stains supported the neoplastic nature of the central odontogenic fibroma-like tumors in the case presented. Laminated psammomatous deposits distinguished the tumors from the world health organization-type central odontogenic fibroma.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
7/33. Juvenile aggressive cemento-ossifying fibroma. A case report.Juvenile Aggressive Cemento-Ossifying fibroma is a benign, fibro osseous neoplasm commonly affecting maxilla but also other bones including mandible, arising in children. It is considered to be a locally aggressive and quickly expansile lesion. Because of its aggressive nature and high recurrence rate, an early detection and a complete surgical excision is essential. A case of Juvenile Aggressive Cemento-Ossifying fibroma in a 9 year old male child who visited the Department of oral medicine and radiology, J.S.S. Dental College and Hospital, Mysore is being reported and discussed.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
8/33. Juvenile aggressive cemento-ossifying fibroma. A case report.Juvenile Aggressive Cemento-Ossifying fibroma is a benign, fibro osseous neoplasm commonly affected maxilla but also other bones including mandible, arising in children. It is considered to be a locally aggressive and quickly expansile lesion. Because of its aggressive nature and high recurrence rate, an early detection and a complete surgical excision is essential. A case of Juvenile Aggressive Cemento-Ossifying fibroma in a 9 year old male child who visited the Department of oral medicine and radiology, J.S.S. Dental college and Hospital, Mysore is being reported and discussed.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
9/33. Salvage of an impacted canine associated with an adenomatoid odontogenic tumour: a case report.The adenomatoid odontogenic tumour (AOT) has been known by a number of descriptive names (adenoameloblastoma, ameloblastic adenomatoid tumour, glandular ameloblastoma, and adenomatoid ameloblastoma) since it was first reported and later recognised as a distinct odontogenic lesion unrelated to ameloblastoma. Although it was considered to be a variant of ameloblastoma at one time leading surgeons to perform unduly aggressive surgery, the treatment outcome experience has borne out the benign, nonaggressive nature of this lesion. The AOT is now considered to be a hamartoma with completely benign behaviour. recurrence seldom if ever occurs after surgical curettage. Thus, it appears needless to extract involved anterior teeth associated with the tumour, especially in children. We report a case in which surgical and orthodontic treatment helped to salvage an impacted mandibular canine associated with an AOT in an adolescent girl. We have not found such a procedure to have been done for this tumour in the literature.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
10/33. tuberous sclerosis.tuberous sclerosis (epiloia, Bourneville-Pringle syndrome) is an inherited disease with an autosomal pattern. Both sexes are affected equally with varied expression in successive generations. Two cases of this unusual disorder in siblings are reported. They illustrate heredofamilial nature, dissimilar expression, mutations, and oral manifestations.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
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