1/13. Solitary fibrous tumour of the parotid gland.Solitary fibrous tumours are rare tumours originally described in the pleura. More recently there have been reports of these tumours arising at other sites including the parotid region. They are characterized histologically by a variety of growth patterns that can be confused by the unwary with other benign or malignant tumours particularly sarcomas. We present a case occurring in the pre-auricular region which presented diagnostic difficulties.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/13. Solitary fibrous tumour of the thyroid gland.Solitary fibrous tumours of the thyroid gland are rare; only five cases have been reported in the literature. Clinically, they present as a long-standing firm mass in the thyroid. Histologically, they show a range of appearances including so-called 'patternless growth pattern', spindle-cell morphology, alternating hypo- and hyper-cellular areas, keloid-like hyalinization and a prominent haemangiopericytoma - like architecture. The behaviour of extrathoracic solitary fibrous tumours is unpredictable and requires careful, long-term follow-up.- - - - - - - - - - ranking = 1.25keywords = gland (Clic here for more details about this article) |
3/13. Solitary fibrous tumour of the face: a rare case report.Solitary fibrous tumour is a rare mesenchymal neoplasm that most commonly involves the pleura. The diagnosis of solitary fibrous tumour is primarily histological. It consists of histological and positive immunohistochemical findings of CD-34 and vimentin. Recently, solitary fibrous tumour has been reported to occur in extrapleural soft tissues, such as the orbit, nasal cavity, abdominal cavity, parotid gland, scalp and neck. In an extensive review of the literature, we found no reports of solitary fibrous tumour arising in the facial soft tissue, other than in the parotid gland. This rare location of an uncommon lesion can lead to a confusing diagnosis. We report a case of solitary fibrous tumour originating in the temporal region of the face, and call for awareness of this tumour among plastic surgeons.- - - - - - - - - - ranking = 0.5keywords = gland (Clic here for more details about this article) |
4/13. Solitary fibrous tumor of the parapharyngeal space: MR imaging findings.We report the MR imaging findings of a solitary fibrous tumor involving the parapharyngeal space. The tumor was a well-circumscribed solid mass with a lobulated contour. It had the same signal intensity as the muscle on T1-weighted MR images, heterogeneously high signal intensity on T2-weighted images, and homogeneous strong enhancement after the administration of contrast material. It mimicked a tumor originating from the deep lobe of the parotid gland.- - - - - - - - - - ranking = 0.25keywords = gland (Clic here for more details about this article) |
5/13. Solitary fibrous tumor of the parotid gland: a case report.The solitary fibrous tumor is traditionally associated with a mesothelial-lined surface. However, any organ with mesenchymal tissue has the potential for developing this tumor; therefore, it has been described in organs not associated with serosal surfaces. We report a case of solitary fibrous tumor of the parotid gland. Microscopically, the tumor showed a patternless arrangement of spindle cells in a fibrotic background and prominent vascular structures of varying size. Tumor cells showed a strong immunoreactivity for CD34 and bcl-2 antigens, but the tissue was negative for antibodies directed against actins, S-100 protein, and cytokeratins. One year after excision, the patient was alive and without evidence of disease.- - - - - - - - - - ranking = 1.25keywords = gland (Clic here for more details about this article) |
6/13. Solitary fibrous tumor of the submandibular gland.solitary fibrous tumors (SFT) are generally benign, well-circumscribed soft-tissue tumors of mesenchymal origin. CD34 antigen expression is characteristic for this tumor. A rare subgroup shows malignant histological patterns with aggressive behavior. The common site of occurrence is the pleura, but various other sites, including the head and neck, have been described. We present a 56-year-old, white, female patient with a solitary fibrous tumor developing in the right submandibular salivary gland. The tumor was surgically removed, and no recurrence or metastases have occurred during the 43 months of follow-up. All solitary fibrous tumors reported in the salivary glands were benign. However, new cases should be presented and followed up carefully to monitor their biological behavior.- - - - - - - - - - ranking = 1.5keywords = gland (Clic here for more details about this article) |
7/13. A case of solitary fibrous tumor of the parotid gland: review of the literatures.We report a rare case of solitary fibrous tumor of the parotid gland. A 47-year-old woman presented with a 3-year-history of left-sided subauricular swelling. Computed tomographic scans and magnetic resonance images revealed a well-defined and dumbbell-shaped mass, measuring about 30 mm in its greatest dimension, in the left parotid gland. Because the tumor occupied both superficial and deep lobes of the gland, she underwent total parotidectomy with preservation of the facial nerve. The microscopic finding showed short-spindle and ovoid cells arranged in a haphazard pattern with interspersed thin collagen fibrils. Immunohistochemically, the tumor cells were strongly positive for CD34, bcl-2 and vimentin, whereas stains for S-100, cytokeratin, smooth muscle actin, collagen type iv and CD117 (KIT) were negative. On the basis of these findings, the tumor was diagnosed as solitary fibrous tumor. Her post-operative course was uneventful, and she is currently free from disease 14 months after surgery. diagnosis, clinical behavior and treatment of solitary fibrous tumor are reviewed from perusal of the literature.- - - - - - - - - - ranking = 1.75keywords = gland (Clic here for more details about this article) |
8/13. Solitary fibrous tumor of the cerebellopontine angle with salivary gland heterotopia: a unique presentation.We report the unique association of a solitary fibrous tumor of the cerebellopontine angle with ectopic salivary gland tissue in a 53-year-old woman. The patient, diagnosed 21 years earlier with a right cerebellopontine angle fibrous meningioma, presented with a recurrent mass, which, upon surgical removal, showed features of a solitary fibrous tumor. Strong and diffuse immunoreactivity to CD34 and BCL-2 and a negative epithelial membrane antigen immunostain confirmed the diagnosis. Admixed with the spindle cell neoplasm, a bland glandular element composed of small glands and variably dilated tubules was noted. The vague tubuloacinar arrangement of the glands and the presence of acinar cells with a granular, periodic acid-Schiff-positive, basophilic cytoplasm, resembling serous type acini, were features of benign, although ectopic, salivary gland tissue. The presence of a myoepithelial cell layer, surrounding some of the acini and highlighted by the smooth muscle actin immunostain, strengthened this interpretation.- - - - - - - - - - ranking = 2.25keywords = gland (Clic here for more details about this article) |
9/13. Solitary fibrous tumor of the thyroid gland.A solitary fibrous tumor is a mesenchymal neoplasm originally described in the pleura. Subsequently, it was found to exist in many extra-pleural sites including the thyroid gland. Herein, we report a case of solitary fibrous tumor of the thyroid gland associated with symptoms of hoarseness of voice in a 45-year-old man. In this report we discuss and illustrate various aspects of this rare tumor including, the gross macroscopic appearance, the histological findings, the immunohistochemical staining properties, the differential diagnosis, and the outcome of our experience regarding fine needle aspiration technique in this particular tumor.- - - - - - - - - - ranking = 1.5keywords = gland (Clic here for more details about this article) |
10/13. Solitary fibrous tumor of the auditory canal.Solitary fibrous tumor (SFT) is an uncommon spindle cell neoplasm of increasing incidence that was originally described to be of pleural origin; however, more recently, SFT has been reported in extrapleural sites, including the orbit, liver, salivary glands, tongue, nose, paranasal sinuses, larynx, retroperitoneum, meninges, and thyroid. The increase in the number of SFTs does not necessarily mean increased incidence of this tumor but rather an increased understanding of this tumor, especially recognition of this tumor in extrapleural locations, which has been aided by immunohistochemical analysis. We report a case of SFT in the auditory canal, which to our knowledge has not been previously reported, as evident by morphologic findings and immunophenotype.- - - - - - - - - - ranking = 0.25keywords = gland (Clic here for more details about this article) |
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