1/10. Postinjection vastus lateralis atrophy: 2 case reports.We report two cases of postsurgical intramuscular meperidine injection with injury to the femoral nerve and subsequent vastus lateralis atrophy. The first case is a patient who had arthroscopic anterior cruciate ligament reconstruction; the second, a patient with a C6-C7 anterior fusion. photographs, radiography, and electrodiagnostic studies clearly depict the nature of the injuries, and their etiology is discussed. These case reports describe a unique neuropathic injection injury that, to our knowledge, has never before been described in the literature.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
2/10. Relapsing lumbosacral plexus neuropathy. Report of two cases.Primary lumbosacral plexus neuropathy (LSPN) is a well-defined syndrome characterized by pain, weakness and atrophy in the distribution of the lumbosacral plexus. Previous reports of LSPN have stressed the benign nature of the syndrome. patients generally have a nearly complete recovery in months to years following the initial event. Two patients presenting with a relapsing form of LSPN are reported. The diagnosis of LSPN was based on clinical and electromyographic features, and no underlying cause was found on initial evaluation or subsequent follow-up over a 6- to 8-year period. We suggest that these patients represent a clinically and possibly pathologically distinct subgroup of LSPN.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
3/10. A new myopathy with tubulomembranous inclusions.A muscle biopsy performed on a 16-year-old boy with progressive myopathy revealed hitherto unrecognized peculiar inclusions which consisted of 3 types of structures. The first type consisted of laminated tubulomembranous structures and most of the inclusions belonged to this type. The lamellae were regularly spaced with a periodicity of 8.5--9 nm and curving a little, and were observed as concentric lamellae according to the plane of sectioning. The second type of inclusions consisted of curvifilamentous material. The third type had the appearance of moderately electron-dense granular material surrounded by a single unit membrane. The origin and nature of these inclusions is obscure, but the diagnosis of some kind of storage myopathy was suspected in this case.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
4/10. Basophilic degeneration of skeletal muscle in hypothyroid myopathy. Histochemical and ultrastructural studies.Morphologic and histochemical studies of basophilic degeneration (BD) of skeletal muscle were performed on a 64-year-old woman with hypothyroid myopathy. The BD had staining characteristics of polysaccharide and similarity to the deposits described in cardiac muscle in five of six muscle groups studied and was absent in the diaphragm. The frequent occurrence of BD at the myotendinous junction suggested the necessity of including this area in muscle biopsy specimens of suspected hypothyroid myopathy. review of the literature indicated a need for more detailed examination of muscle specimens of these patients to determine the clinical implication and biochemical nature of the BD. To my knowledge, the demonstration of a close association of BD and leptomeres and the presence of crystalline structures within the BD have not been described previously.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
5/10. Facilitating myasthenic syndrome and quadriceps myopathy.A patient presented with myasthenic syndrome apparently not related to any neoplasia. A peculiar myopathy characterized by absolute predominance (99.50%) and atrophy of type 2A muscle fibers was found in both quadriceps muscles. It is difficult to determine the relation between the myasthenic syndrome and the localized quadriceps myopathy for which a congenital nature is suggested.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
6/10. The spectrum of disease in weakness and wasting of the quadriceps muscles. case reports.Three patients who presented with weakness and wasting of the quadriceps muscles ('quadriceps myopathy'), are reported. In each, electrophysiological and biopsy studies revealed completely different pathological processes, including motor unit disease, polymyositis and muscular dystrophy. Double biopsies performed in 2 of the patients showed the disease process to involve upper as well as lower limbs. The diffuse and heterogeneous nature of this form of neuromuscular disease is confirmed.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
7/10. A case of charcot-marie-tooth disease mimicking Friedreich's ataxia: is there any association between friedreich's ataxia and charcot-marie-tooth disease?The authors report a case of charcot-marie-tooth disease that mimicked Friedreich's ataxia and featured impaired tendon reflexes in the limbs, incoordination mimicking cerebellar disease in the extremities, extensor plantar responses on both sides, bilateral foot deformity, imparied position sense in the toes, absent vibratory sense in the distal parts of the legs and minimal distal weakness with wasting. Motor conduction velocity in the upper limbs was substantially reduced. Other cases similar in nature reported in the literature resemble spino-cerebellar degeneration in general, and Friedreich's ataxia, in particular. It is emphasized that the natural history, EMG, motor conduction velocity studies and examination of other affected members of the family permit the correct diagnosis to be made in such cases. It is also emphasized that patients similar to the one reported here may also resemble, and should be differentiated from, cases of familial dorsal column ataxia (Biemond type). Stress is put upon the fact that when charcot-marie-tooth disease mimicks spino-cerebellar degeneration, substantial slowing of motor conduction in the upper limbs is generally sufficient to establish the diagnosis. The relation between Friedreich's ataxia an charcot-marie-tooth disease is reviewed and it is concluded that these two disorders are distinct clinical and pathological entities.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
8/10. Autosomal dominant late adult spinal muscular atrophy, type Finkel.We describe clinical and genetic data from the study of two families with 80 members affected with the autosomal dominant, slowly progressive spinal muscular atrophy of late onset (average 48.8 years), first described by Finkel in 1962. electromyography and muscle biopsy of a number of patients confirmed the neurogenic nature of the conditions. Unusual findings in this disorder were cramps, spontaneous fits of suffocation, and symptomatic myotonia. Other manifestations are slow loss of muscle strength and progressive proximal atrophy, which starts in the lower limbs and progresses to the upper limbs; hypoactive or absent tendinous reflexes; and generalized fasciculations. Sensory and cranial nerve function is unimpaired. Probabilities for genetic counseling are evaluated by means of a method adequate to the late-onset nature of the condition.- - - - - - - - - - ranking = 2keywords = nature (Clic here for more details about this article) |
9/10. Isolated and painless (?) atrophy of the infraspinatus muscle. Left handed versus right handed volleyball players.The suprascapular nerve originates from the upper trunk of the brachial plexus or less frequently from the root of C5. It runs a short way and crosses the suprascapular notch. It innervates the supraspinatus muscle and the acromioclavicular and glenohumeral joints. Then, it crosses the lateral edge of the spine of the scapula passing through the spinoglenoid notch, and innervates the infraspinatus muscle. These are potential sites of injury to the suprascapular nerve. Three cases of suprascapular nerve entrapment causing an isolated infraspinatus muscle atrophy in volleyball players were studied. It is suggested the hypothesis that the nature of the smash, in which the athlete uses the arm violently, more than does in volleyball service or in the art of reception, is the key to the pathogenesis of the lesion in volleyball players.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
10/10. Focal atrophy of the multifidus muscle in lumbosacral radiculopathy.A patient with compelling clinical and electrodiagnostic evidence of a right L5 radiculopathy had focal atrophy of the multifidus at the appropriate level, which served to confirm the radicular nature of the process. The multifidus muscles are innervated by a single root, in contrast to the polysegmental innervation of the rest of the paraspinal muscle mass. Imaging studies may complement needle electromyography in the evaluation of this important structure.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
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