Cases reported "Mouth Neoplasms"

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1/8. Basaloid squamous cell carcinoma of oral cavity and oropharynx.

    Basaloid squamous cell carcinoma is a variant of squamous cell carcinoma with distinctive histological and immunohistochemical characteristics and aggressive behaviour involving predominantly the upper aerodigestive tract. We describe the clinicopathological findings, along with immunohistochemical investigations, in 5 new cases with carcinoma localized in oral cavity and oropharynx.
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2/8. Basaloid squamous cell carcinoma of the oral mucosa: a new case and review of 45 cases in the literature.

    Basaloid squamous cell carcinoma (BSCC) of the oral mucosa other than the tongue is uncommon. We report a case of a 67-year-old man who diagnosed with Stage I BSCC in the floor of the mouth. This early stage presentation carries a considerably better prognosis. Clinical summary of 46 cases of oral BSCC indicated that the tongue base was the most preferred site (61%). The patients were 19 males and 15 females with the mean age of 61 years (n=34). Most presented with Stage III or IV disease (62%). Even at the initial presentation, 47% had cervical lymph node metastases. Its aggressive clinical behaviour was characterized by a high incidence of local recurrence (32%), regional lymph node metastases (52%), and mortality rate (38%). Because of the advanced stage at presentation, oral BSCC is prognostically worse.
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3/8. Lymphoepithelioma-like carcinoma of oral cavity: report of three cases and literature review.

    Lymphoepithelioma-like carcinoma is a rare tumour in the oral cavity and is characterized histologically by non-keratinizing, undifferentiated squamous cell carcinoma with lymphocytic infiltration. Three consecutive cases of intraoral lymphoepithelioma-like carcinoma are reported. A review of the literature reveals a similar biological behaviour to that of nasopharyngeal lymphoepithelioma: a high incidence of cervical nodal spread and remarkable radiosensitivity. Chemotherapy should be considered when nodal or distant metastases are present. The association of the Epstein-Barr virus with this tumour remains unclear but our experience suggests a positive correlation in Chinese individuals.
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4/8. Basaloid squamous cell carcinoma report of a case and review of literature.

    Basaloid squamous cell carcinoma (BSCC) is an aggressive distinct variant of squamous cell carcinoma that mandates recognition as a separate entity owing to the difference in its clinical behaviour. Histologically this tumor can mimic other neoplasms like adenoid cystic carcinoma, neuroendocrine carcinoma and basal cell adenocarcinoma. BSCC occurs most commonly in older men and has a site predilection for the upper aero-digestive tract. We report a case of basaloid squamous cell carcinoma for its relative rarity, which was diagnosed in a 52 year old woman, with a brief review of literature.
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5/8. Proliferative verrucous leukoplakia and field cancerization: report of a case.

    Proliferative verrucous leukoplakia (PVL) is a multi-focal oral pre-malignant lesion, proliferative in nature, with a tendency to recur despite adequate therapy, and a high rate of malignant transformation. The field cancerization phenomenon may explain the characteristic behaviour of PVL. A case of PVL is presented and the field cancerization concept is discussed.
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6/8. Necrotizing sialometaplasia--a malignancy simulating oral lesion.

    A case of necrotizing sialometaplasia is reported in a 63-year-old white male. The lesion appeared as an ulcerated and painful lesion inside the left ramus mandibulae. An incisional biopsy was performed and reported as well-differentiated squamous cell carcinoma. A few days after the initial biopsy was taken the necrotizing tissue disappeared and the ulcer started to heal. A new, excisional biopsy was performed. The initial diagnosis was revised and the lesion reported as necrotizing sialometaplasia. Two weeks after the excisional biopsy complete healing was obtained. The clinical and histological findings are discussed in relation to the different stages through which a necrotizing sialometaplasia might develop. From a differential diagnostic point of view it is important for both the clinician and pathologist to be aware of the lesion's behaviour during the different stages of development.
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7/8. Haemangiopericytoma of the floor of the mouth. A case report.

    Haemangiopericytoma of the floor of the mouth with metastases to the lumbar spine in a 23-year-old black woman is described. She represents the 36th patient with oral cavity haemangiopericytoma and the 4th with a floor of mouth lesion. The aggressive behaviour of haemangiopericytoma and its resistance to all forms of recommended treatment was shown in this patient.
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8/8. dermatofibrosarcoma protuberans of the upper lip: an overview and a case report.

    dermatofibrosarcoma protuberans is a slow-growing but locally aggressive malignant neoplasm of the skin. The preferential locations are on the trunk and proximal extremities but it can occur in the head and neck region in about 15% of the cases. This is a report of such a case and a review of the literature of head and neck cases attempting to analyse the profile of patients and surgical prognosis factors. The recurrence rate is important (20% to 55%) and dependent on the free tissue margins. Those margins are at least 3 cm in all directions; this is difficult to assess in the head and neck region because of both functional and cosmetic aspects. Distant metastases are rare but related to a long recurrence history. This behaviour gives the impression that prognosis is poorer for dermatofibrosarcoma in the head and neck than within other locations.
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