1/12. Isolated gastric malakoplakia: a case report and review of the literature.A 62-year-old African American woman presented with weight loss and dyspepsia. She did not have any clinical evidence of immunodeficiency. Upper gastrointestinal endoscopy revealed multiple small polypoid lesions in the gastric body and fundus that appeared larger and more erythematous than usual fundic gland polyps. Examination of biopsy specimens revealed an infiltrate of large histiocytes with eosinophilic granular cytoplasm located in the lamina propria and containing Michaelis-Gutmann bodies. These histologic findings were diagnostic of gastric malakoplakia. Gastrointestinal malakoplakia is uncommon, and exclusive gastric involvement is extremely rare. Because occult bacterial infection has been postulated as the underlying cause of malakoplakia, the presence of helicobacter pylori infection was investigated using immunohistochemical and serologic techniques, and the presence of yersinia enterocolitica or yersinia pseudotuberculosis infection was investigated by polymerase chain reaction assay. There was no evidence of H pylori, Y enterocolitica, or Y pseudotuberculosis in these biopsy specimens, and there was no evidence of malakoplakia or concurrent malignancy at any other site. Follow-up examination 12 months later revealed no endoscopic or histologic improvement.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/12. Malakoplakia of the prostate.Malakoplakia of the prostate is a rarely reported granulomatous inflammatory disorder which may clinically mimic carcinoma of the prostate gland. A case of a 70-year-old man, with long follow-up, is reported. Histologic diagnosis allows for effective antibiotic treatment.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
3/12. malacoplakia of the thyroid gland.A case of malacoplakia of the thyroid gland is described in a 50-year-old Japanese woman. This lesion clinically mimicked a malignant neoplasm, and the true diagnosis of malacoplakia was made only after histologic examination; light microscopy revealed a granulomatous nodule with an accumulation of von Hansemann's histiocytes containing PAS-positive and von Kossa's-positive intracytoplasmic and extracytoplasmic inclusions known as Michaelis-Gutmann bodies. There were some foci consisting of neoplasm-like or hyperplastic residual follicles within the lesion. Electron microscopically, a small number of bacilliform organisms were demonstrated within the lesion. X-ray microanalysis of Michaelis-Gutmann bodies was performed and revealed the presence of phosphorus, calcium, iron, and chloride. It is suggested that the malacoplakic lesion may be associated with the hyperplastic or neoplastic follicular lesion, and bacterial infection could be important in the causation of malacoplakia of the thyroid gland.- - - - - - - - - - ranking = 6keywords = gland (Clic here for more details about this article) |
4/12. Prostatic malacoplakia. An ultrastructural and immunohistochemical study.A case of malacoplakia of the prostatic gland associated with prostatic nodular hyperplasia from a 69 years old man was presented, and its light and electron microscopic and immunohistochemical features were discussed along with its pathogenesis. This lesion was incidentally found in a transurethral prostatectomy specimen, and consisted of large number of epithelioid cells in which were typical cytoplasmic inclusions known as Michaelis-Gutmann bodies. Ultrastructurally, these inclusions showed a dense, central calcified bodies of various developmental stages. Immunohistochemical study using antilysosomal antibody revealed no lysosomal activity. Based on these findings, we could suspect that main problem for this development of malacoplakia is altered intracellular digestion process of foreign biologic materials.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
5/12. Transrectal ultrasound and fine needle aspiration for malacoplakia of the prostate.Clinically, malacoplakia of the prostate gland may mimic prostatic carcinoma. We report a case of prostatic malacoplakia in which transrectal ultrasound of the prostate was most compatible with carcinoma. However, fine needle aspiration cytology and biopsy revealed the classical histopathological features of malacoplakia so that a correct diagnosis could be made.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
6/12. Malakoplakia of the parotid gland.Xanthogranulomatous inflammation is an ubiquitous process that is most commonly observed in the kidney but may be observed in other organs. We report a case of xanthogranulomatous inflammation occurring in an enlarged parotid gland of a 65-year-old man as a result of salivary duct obstruction from sialolithiasis. We discuss the common histologic features and probably common aetiology of several inflammatory xanthograulomatous processes including malakoplakia.- - - - - - - - - - ranking = 5keywords = gland (Clic here for more details about this article) |
7/12. malacoplakia of Bartholin's gland.Two cases of malacoplakia involving bartholin's glands occurred in postmenopausal women. Grossly the lesions were ovoid cysts with rubbery, soft walls. Microscopically there were sheets of von Hansemann's histiocytes and rare Michaelis-Gutmann bodies. After surgical excision, both patients remained asymptomatic. These cases involving bartholin's glands are, to our knowledge, the first reported in the female genital tract.- - - - - - - - - - ranking = 6keywords = gland (Clic here for more details about this article) |
8/12. Malakoplakia of prostate gland.Malakoplakia of the prostate gland has rarely been reported. Its presentation often mimics carcinoma of the prostate. We report a case in a sixty-three-year-old patient who had a previous history of other granulomatous disease.- - - - - - - - - - ranking = 5keywords = gland (Clic here for more details about this article) |
9/12. Malakoplakia of the adrenal gland.The clinical and pathological features of a case of malakoplakia of the adrenal gland occurring in a woman with escherichia coli infection are described. This lesion mimicked a neoplasm, the true diagnosis only being revealed by histological examination. The light and electron microscopic features are described and it is suggested that malakoplakia is due to an abnormal macrophage response to E coli infection.- - - - - - - - - - ranking = 5keywords = gland (Clic here for more details about this article) |
10/12. Malakoplakia of the prostate gland--report of two cases and review of the literature.Malokoplakia of the prostate is extremely rare. We report two cases of prostatic malokoplakia in one 60-year-old and one 64-year-old Libyan man, who both were presented with enlarged prostate containing firm to hard nodules. These cases may be misdiagnosed as carcinoma clinically, but the histology points out the correct diagnosis with the presence of Michaelis-Gutmann bodies in the proliferating histiocytes.- - - - - - - - - - ranking = 4keywords = gland (Clic here for more details about this article) |
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