1/3. Periocular keratoacanthoma: clinical features, pathology, and management.PURPOSE: To review the clinical features and results of surgical treatment of keratoacanthoma of the eyelids. DESIGN: Retrospective, interventional case series. PARTICIPANTS: Ten patients. methods: Chart review of all eyelid keratoacanthomas treated between 1992 and 2001. MAIN OUTCOME MEASURES: Adequate excision, recurrence rate, and complications. RESULTS: Patient ages ranged from 27 to 78 years, with a mean age of 59 years. Six patients were male and four were female. The lesion was found on the lower lid in five patients, upper lid in two, medial canthus in two, and lateral canthus in one. The maximum diameter of the lesion varied from 2 to 25 mm, with a mean of 7.2 mm. All lesions were treated by surgical excision, with frozen-section control of margins in five cases. All lesions were excised completely with clear resection margins, and there were no cases of recurrence. The only complication was a minor wound infection in one patient. Mean follow-up was 34.5 months. CONCLUSIONS: Because of the aggressive nature and uncertain relationship to squamous cell carcinoma, we recommend excision of periocular keratoacanthoma. Surgical excision of eyelid keratoacanthoma provides good results and a very low risk of recurrence. Frozen-section control of margins should be used in selected cases to ensure complete excision.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
2/3. Facial keratoacanthoma.The keratoacanthoma is a common tumor of hair follicle origin that appears predominantly on sun-exposed skin of elderly persons. Approximately 80% of the tumors arise on the face. It is characterized by the rapid growth of a painless, dome-shaped, 10 to 25 mm solitary lesion with a central keratinous plug that undergoes spontaneous involution over 6 to 12 months, leaving behind a puckered scar. Alarming growth and early histologic appearance (pseudocarcinomatous infiltration, cell atypicality, mitoses) are suggestive of squamous cell carcinoma, but biologic behavior and tumor architecture confirm its benign nature. However, evidence that all keratoacanthomas regress is lacking, malignant transformation has been reported, and less than excisional biopsy may render a difficult histologic diagnosis either inconclusive or erroneous, even in expert hands. Excisional biopsy is recommended as expedient and definitive management that offers optimal prognosis. Local flap or full-thickness graft closure affords cosmetic results that are superior to those provided by other treatment methods.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |
3/3. A case of Grzybowski's generalized eruptive keratoacanthomas.We report a case of Grzybowski's generalized eruptive keratoacanthoma which demonstrates the characteristic features of this rare condition. The recurring nature of the eruption each summer supports the suggestion that UV irradiation may act as a precipitating factor in eruptive keratoacanthoma.- - - - - - - - - - ranking = 1keywords = nature (Clic here for more details about this article) |