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1/11. Neonatal renal candidal bezoar.

    Renal candidal bezoar is uncommonly encountered in neonatal intensive care. An affected neonate who improved only after surgical removal of obstructive fungus from the renal pelvis and local irrigation with amphotericin b is described. The need for early consideration of surgical intervention is stressed.
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ranking = 1
keywords = candida
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2/11. Candidal infections in neonates of very low birth weight.

    Candida infections represent a serious cause of morbidity and mortality in sick low birth weight infants cared for in the neonatal intensive care unit. Often, the infection goes undiagnosed, or the candidal isolate is regarded as a contaminant. There is also fear of potential toxicity from treatment. We have reported a case in which recovery occurred without antifungal therapy, and reviewed the current literature regarding this potentially devastating infection.
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keywords = candida
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3/11. Phycomycotic abscesses in a preterm infant.

    We report a case of neonatal infection with rhizopus, one of the Mucoraceae family. Human infection is rare but the mortality is high without prompt, correct treatment. The infant had a simultaneous candida septicaemia secondary to colonisation of a central venous line. Serial C reactive protein estimations are valuable in monitoring treatment.
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ranking = 0.2
keywords = candida
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4/11. Neonatal candida septicaemia: diagnosis on buffy smear.

    We report a case of neonatal candida septicaemia diagnosed by examination of a buffy smear. This would seem to be a fairly simple test for a disease where a good prognosis is dependent on rapid diagnosis and isolation using standard culture techniques is notoriously unforthcoming.
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keywords = candida
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5/11. anuria in a premature infant due to ureteropelvic fungal bezoars.

    Systemic candidiasis with renal involvement is a well recognised complication of intensive care in premature newborns. However, the development of reversible obstructive oliguric acute renal failure has not been well documented. We report a premature infant who developed anuria associated with bilateral candidal bezoar formation in the renal collecting system. The sonographic appearance of the renal fungus balls is described. Treatment by surgical removal of the bezoars, open placement of nephrostomy tubes and intravenous antifungal therapy resulted in apparent complete recovery.
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ranking = 0.2
keywords = candida
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6/11. Surgical therapy of pulmonary thrombosis due to candidiasis in a premature infant.

    We report a case of surgical removal of a pulmonary thrombosis in a premature infant with candidemia. The pulmonary thrombotic material contained candida albicans. Following surgical therapy the child recovered soon and candidemia did not recur. We conclude that surgical treatment of pulmonary thrombosis can be successfully done even in premature infants.
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ranking = 0.2
keywords = candida
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7/11. The persistent loop sign in neonatal necrotizing enterocolitis: a new indication for surgical intervention?

    A new radiographic sign in neonatal necrotizing enterocolitis is described. Five patients with necrotizing enterocolitis exhibited an unchanging dilated loop of small bowel, which was followed by perforation in 3 infants; the other 2 had surgical and/or autopsy corroboration of profound bowel-wall necrosis. It is suggested that infants with a "persistent loop" be considered candidates for laparotomy.
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ranking = 0.2
keywords = candida
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8/11. anuria from candida pyelonephritis and obstructing fungal balls.

    A premature newborn male required intensive care and prolonged antibiotic therapy for respiratory distress. Acute renal failure developed from bilateral obstructive candida pyelonephritis complicating systemic candida albicans infection. Necropsy also revealed organizing subarachnoid hematoma and granulomatous candida meningoencephalitis.
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ranking = 1.2
keywords = candida
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9/11. Assessment of antifungal therapy in an 800-gram infant with candidal arthritis and osteomyelitis.

    A 720-g premature newborn developed disseminated candidiasis during treatment with systemic antibiotics and total parenteral nutrition through an umbilical arterial catheter. Clinical features were typical for candidal skeletal infection at this age and included warmth and fusiform swelling of the lower extremities together with radiographic evidence of osteolysis and cortical bone erosion. candida albicans was cultured from blood, urine, joint fluid, and a bone aspirate. The infection was cured with a 44-day course of amphotericin b and flucytosine (5-fluorocytosine). Antifungal therapy was monitored closely with serum drug levels and laboratory tests for bone marrow toxicity and renal dysfunction. serum levels of both drugs were comparable to those achieved in older patients treated with similar doses. Significant concentrations of amphotericin b were detected in serum four and 17 days after completion of therapy, indicating a slow rate of elimination similar to that which occurs in adults. There was no evidence of drug-induced toxicity other than transient elevation in the fractional urinary excretion of sodium. This suggests that antifungal therapy may be effectively and safely administered to infants in dose schedules similar to those used for older patients.
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keywords = candida
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10/11. Intrauterine candida infection in premature baby.

    An autopsy case of pulmonary candidiasis occurring in an neonatal girl was reported. The mycological examination of the lung take at autopsy revealed only candida albicans and followed by the elucidation under the microscopic sections prepared with special stains; periodic acid-Schiff and methenamine silver, in the lung, stomach, umbilical cord, and amnion. The presence of candida vaginitis in her mother supported the concept that candida albicans was the etiological agent of the pulmonary candidiasis.
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keywords = candida
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