1/6. The skin as the possible reservoir for candida albicans in the oculocutaneous candidiasis of heroin addicts.We describe 2 patients who injected themselves with the same brown heroin a few days before hospitalization. The first patient presented with characteristic oculo-cutaneous candidiasis. blood samples remained sterile during the so-called 'septicemic syndrome' which represents the first phase of this syndrome and were positive for candida albicans only when cutaneous nodules developed. The second patient was hospitalized for a stomach perforation and had no cutaneous or ocular candida involvement. Both patients were unusually colonized by C. albicans on their skin (particularly on hairy zones). These observations support the hypothesis that the skin may constitute the reservoir for C. albicans in oculo-cutaneous candidiasis.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
2/6. Candidal costochondritis responsive to ketoconazole in an iv drug abuser.Infections caused by candida albicans have been reported in many organ systems in intravenous drug users. amphotericin b (Fungizone) has been shown to be effective in treatment. However, because of its numerous side effects and difficulty in maintaining intravenous access in this population, the agent is difficult to use. ketoconazole (Nizoral), administered orally, is a more convenient and better tolerated agent and was efficacious in the case of candidal costochondritis described here. Further evaluation of ketoconazole is needed to better define its role in the treatment of disseminated candidiasis, particularly in cases associated with intravenous drug abuse.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
3/6. Candida endophthalmitis after heroin abuse.Three cases of ocular candidosis involving heroin abusers have been observed in 1983 in Toulouse department of ophthalmology. These three patients had used iranian brown heroin. Twenty similar cases have been published in these last years. This new pathology can be explained on two reasons. The first is that the drug abusers have some immunity pertubation; however, immunity exploration in these patients does not reveal any immunodeficiency. The second reason, certainly more important, is the method of using heroin. The diagnosis of Candida endophthalmitis of course based on clinical context must be proved by biological tests. candida albicans is never identified in aqueous humor. For this reason, it seems very interesting to detect anti-candida antibodies in aqueous humor. It has been used as methods of dosage laser Nephelemetry for IgG and immunofluorescence for candidosis antibodies. The criterion used is similar to the toxoplasmosis coefficient established by Desmonts (3). In two cases, this test was the only way that permits us to have certitude of candidosis ocular diagnosis. Otherwise the observations show that anterior chamber punction is more significant when there is an anterior uveitis.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
4/6. Renal transplantation in heroin addicts.On the basis of our experience, therefore, we believe that the reformed heroin addict is a good candidate for cadaveric donor renal transplantation if he can be discouraged from returning to heroin use. The fact that the majority of the patients in our study returned to marijuana smoking after transplantation has raised the issue of its role as a possible immunosuppressant.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
5/6. Candida endophthalmitis in a heroin addict: a case report.Metastatic candida endophthalmitis presented as a unilateral panuveitis in an apparently healthy drug addict. diagnosis was confirmed by vitrectomy. The eye made an excellent response to treatment with the new antifungal drug, ketoconazole, and 5-fluorocytosine. Problems raised in the diagnosis and management of this infection are discussed.- - - - - - - - - - ranking = 1keywords = candida (Clic here for more details about this article) |
6/6. En bloc chest wall resection for candidal costochondritis in a drug addict.A case of Candida costochondritis seen initially as a chest wall tumor in a narcotic addict is reported. Bone and cartilage are rare sites of Candida infection from whatever cause. Since 1973, only 6 cases of Candida costochondritis have been reported; 5 were complications of thoracic operations and the other, of intravenous hyperalimentation. Treatment by a one-stage en bloc resection of chest wall, and reconstruction by rib graft and Marlex mesh resulted in cure in our patient, without complications.- - - - - - - - - - ranking = 4keywords = candida (Clic here for more details about this article) |