11/108. Immunoperoxidase technique for detecting spirochetes in tissue sections: comparison with other methods.BACKGROUND: With the increasing incidence of human immunodeficiency virus (hiv) infection and immunosuppressive therapy, the incidence of syphilis has been increasing. Given the fact that the above conditions may mask or obscure the usual clinical signs and symptoms of syphilis, a means of enhanced detection is essential. AIMS methods: The purpose of this study was to determine whether an immunoperoxidase method using an antibody against treponemes would increase the sensitivity and specificity of diagnosis in biopsies of patients with secondary syphilis. This was compared to serology and silver stain in cases of known syphilis. RESULTS: Immunoperoxidase for treponemes was at least as sensitive (9/10) as pathology (9/10), and more sensitive than conventional silver stain (6/10) or serology (7/10). CONCLUSIONS: In those equivocal cases of secondary syphilis, where confirmation is essential, immunoperoxidase for treponemes may be a useful adjunct.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
12/108. Mycobacterium thermoresistible recovered from a cutaneous lesion in an otherwise healthy individual.This is the first report of coinfection by Mycobacterium thermoresistible and mycobacterium fortuitum and only the fifth case of human infection by M. thermoresistible reported in the world literature.- - - - - - - - - - ranking = 2keywords = infection (Clic here for more details about this article) |
13/108. Papular-purpuric gloves and socks syndrome in hiv-positive patients.Three hiv-positive women showed clinical signs of papular-purpuric gloves and socks syndrome and serologic evidence of acute parvovirus B19 infection. The course of the disease was complicated by anemia and persistent skin lesions, probably related to inadequate immune response. Because anemia in AIDS patients may be due to many causes, the history of recent parvovirus B19 infection is helpful in suggesting the etiologic diagnosis.- - - - - - - - - - ranking = 2keywords = infection (Clic here for more details about this article) |
14/108. White grain mycetoma caused by a Cylindrocarpon sp. in india.We describe a case of white grain eumycetoma of the foot of an Indian male caused by a slow-growing, poorly sporulating fungus that does not match any known agent of this infection. Histologic examination of a biopsy tissue specimen showed oval, lobular, white granules composed of hyaline, septate hyphae, and thick-walled chlamydospores. culture of granules from a draining sinus yielded compact, very-slow-growing, poorly sporulating colonies producing a strong reddish brown pigment that diffused into the medium. The fungus was identified as a Cylindrocarpon sp. based on the development of rare cylindrical conidia borne from solitary phialides lacking collarettes, in addition to chlamydospores formed singly or in short chains.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
15/108. Cutaneous blastomycosis in new brunswick: case report.blastomycosis is a fungal infection of immunocompetent hosts. We present a case of cutaneous blastomycosis acquired in new brunswick, which provides evidence that this disease is endemic in Atlantic canada. This case also demonstrates that the diagnosis of blastomycosis may be elusive. Perseverance, a high index of clinical suspicion and close cooperation with the microbiology laboratory may be required to diagnose this uncommon condition.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
16/108. Isolation of both sporothrix schenckii and nocardia asteroides from a mycetoma of the forefoot.mycetoma is a localized primary subcutaneous infection due to fungi (eumycetoma) or aerobic actinomycetes (actinomycetoma). We report a patient who acquired an implantation infection on the forefoot following a motorcycle accident in Crete. Both sporothrix schenckii and nocardia asteroides were isolated simultaneously from the lesion. Under combined therapy with itraconazole and trimethoprim-sulphamethoxazole for 7 months the lesion healed completely. A combination of causative organisms in mycetomas is rare, and the combination of S. schenckii and N. asteroides together has not been reported from one lesion.- - - - - - - - - - ranking = 2keywords = infection (Clic here for more details about this article) |
17/108. Madura foot: treatment of Nocardia nova infection with antibiotics alone.This case report documents the presentation of a 29-year-old woman with a deep Nocardia nova infection of the foot involving the bones. The patient responded well to prolonged antibiotic therapy, with essentially complete resolution of her symptoms. The results suggest that surgical intervention in these unusual cases may be unnecessary and that good clinical results can be obtained pharmacologically.- - - - - - - - - - ranking = 5keywords = infection (Clic here for more details about this article) |
18/108. Nocardia brasiliensis infection seen on grafted skin of the dorsum of a foot.For the past 4 years a 23 y-old female has noticed erythema on the dorsum of the right foot, where skin was grafted due to a traffic accident 20 years ago. She visited the Department of dermatology of Gifu Prefectural Hospital on Oct. 19, 1998; her general health was good. physical examination disclosed a swelling with erythema, papules and pustules on the dorsum of the right foot. The results of routine laboratory investigations were within normal limits except for the white blood cell count (11,300/mm(3)), blood sediment rate (25 mm/hrs), C reactive protein (1.21) and rheumatoid factor (x 16.6). Several yellowish and verrucous or wrinkled colonies were grown on Sabourauds agar culture from the biopsied specimen of the foot. Histopathological features showed epidermal hyperplasia with elongation of rete ridges and granulomatous changes in the dermis; many mononuclear and giant cells were present, and several positive fine filamentous and irregularly branching structures with PAS and Grocott stains were seen in the granulomatous nests. Both clinical and histopathological features led to speculation of Nocardia infection, and Nocardia brasiliensis was determined. The patient was treated by surgical total resection including the grafted skin. Although a soybean-sized nodule was seen on the border of the skin-graft of the foot three months later, there was no recurrence after the local resection.- - - - - - - - - - ranking = 5keywords = infection (Clic here for more details about this article) |
19/108. Painful blistered hands and feet.CAE is a self-limiting toxicity seen with several types of high-dose chemotherapy. Treatment of these patients requires pain management and supportive therapy, including wound care that promotes healing, comfort, mobility, and quality of life and prevents infection. Oncology nurses play an important role in monitoring patients for CAE and providing supportive care.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
20/108. Papular-purpuric gloves-and-socks syndrome with bloody bullae.Papular-purpuric gloves-and-socks syndrome (PPGSS) is a disease characterized by itchy, painful acral erythema with edema, confluent papules, and purpura in a gloves-and-socks distribution and is associated with fever and mucosal lesions. parvovirus B19 and other viral infections have been proven to be causative agents of this syndrome. Its histological findings have been the non-specific ones of interface dermatitis. Here, we report a case of PPGSS in a 44-year-old man that we believe to be the first such case in japan. He developed, within one day, a painful edematous eruption with confluent papules and purpura on his hands and feet accompanied by high fever. A unique clinical manifestation in this case was multiple bloody bullae on the toes, which have not been previously described. Serological tests were negative for parvovirus B19, cytomegalovirus, and measles virus.- - - - - - - - - - ranking = 1keywords = infection (Clic here for more details about this article) |
| <- Previous || Next -> |