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1/10. Recurrent inflammation in a site of previous necrotising fasciitis during intravenous CMF chemotherapy.

    We present the case history of a patient with breast carcinoma who developed repeated inflammation at the site of previous necrotising fasciitis following each cycle of intravenous CMF chemotherapy. This complication has not previously been reported.
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ranking = 1
keywords = cycle
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2/10. endometriosis on laparotomy scar. A three-case report.

    endometriosis of surgical scar is a rare late complication of cesarean section. 3 cases of endometriosis after Pfannenstiel-type laparotomy are reported. The typical surgical presentation, present in all 3 cases, is a nodule on laparotomy scar after cesaren section, spontanously painful during the menstrual period. Ultrasound, performed in two cases, and cytological examination, performed in one, proved to be ineffective in establishing the diagnosis. The histopathological analysis of surgical specimens revealed in all cases multiple foci of well developed endometrial tissue scattered in a sclerotic stroma. Both stromal and glandular components of the endometrial mucosa were present showing the typical changes of the various phases of the menstrual cycle. In our opinion, an accurate clinical history should directly lead the surgeon to the excision with inclusion of the needle tract, whenever biopsy is performed. Surgical excision is at present the most appropriate diagnostic and therapeutic procedure.
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ranking = 89.183437103002
keywords = menstrual cycle, cycle
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3/10. Cesarean scar endometriosis. A report of two cases.

    BACKGROUND: Extrapelvic endometriosis is a fairly rare phenomenon. The majority of extrapelvic endometriosis involves scar tissue following obstetric/gynecologic procedures. cesarean section scar endometriosis may be more common than reflected in the literature and has a distinct presentation and treatment. CASES: Two patients with histories of cesarean sections presented with a painful, enlarging mass involving the cesarean section scar. The pain was cyclic and strongest just prior to menstruation. Both patients were treated with surgical excision, and both specimens had endometriosis confirmed by histopathology. CONCLUSION: endometriosis involving a cesarean section scar may be more common than thought. patients typically present with a history of cesarean section or other obstetric/gynecologic surgery and are found to have a mass involving the scar, with symptoms intensifying prior to each menstrual cycle. Surgical excision is the treatment of choice, providing both diagnostic and therapeutic intervention.
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ranking = 89.183437103002
keywords = menstrual cycle, cycle
(Clic here for more details about this article)

4/10. Dramatic response of choroidal metastases from breast cancer to a combination of trastuzumab and vinorelbine.

    We report the case of a 57-year-old woman with unilateral choroidal metastases from HER-2-positive breast cancer. She was given trastuzumab and vinorelbine with complete resolution of her visual defect after one cycle of treatment. This article illustrates that treatment using trastuzumab-containing chemotherapy regimens in HER-2-overexpressing breast cancer patients with choroidal metastases may be an alternative therapeutic strategy to initial orbital irradiation.
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keywords = cycle
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5/10. Treatment of facial scarring and ulceration resulting from acne excoriee with 585-nm pulsed dye laser irradiation and cognitive psychotherapy.

    BACKGROUND: Self-inflicted skin ulcers and scars are often observed in patients with compulsive skin picking. The term "neurotic excoriation" has been used to describe this condition and may or may not coexist with other true skin pathologies, such as acne. The condition poses a diagnostic and treatment challenge because patients often also have an undiagnosed underlying psychologic disorder. case reports: Two patients with numerous linear and stellate facial ulcers and hypertrophic and erythematous scars were diagnosed with acne excoriee in the setting of an obsessive-compulsive disorder linked to emotional stress and anxiety. The scars were treated with a 585-nm flashlamp-pumped pulsed dye laser using a 7-mm spot size, 1.5-msec pulse duration, and fluence range of 4.5 to 6.0 J/cm(2). The patients received concomitant cognitive psychodynamic therapy to halt the cycle of impulse-driven skin picking and ulcer/scar formation. Marked clinical improvement of the scars and successful treatment of the acne excoriee were achieved with this combination approach. Relapses occurred when psychodynamic intervention was interrupted. CONCLUSION: The 585-nm flashlamp-pumped pulsed dye laser improves the appearance of hypertrophic erythematous facial scars and ulcers in patients with severe acne excoriee. Proper diagnosis of underlying impulse-control disorders and ongoing psychodynamic therapy is necessary to maintain improvement.
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keywords = cycle
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6/10. Cytomorphological spectrum in scar endometriosis: a study of eight cases.

    OBJECTIVE: endometriosis due to ectopic endometrial tissue that responds to hormonal stimulation and is extremely rare in a surgical scar appearing in 0.1% of women who have undergone Caesarean section. Fine needle aspiration cytology (FNAC) can be a valuable diagnostic aid in the evaluation of these subcutaneous abdominal masses. methods: We present the cytomorphological spectrum in eight cases of abdominal wall endometriosis diagnosed by FNAC over a 6-year period (June 1998-June 2004) in Mubarak Al-Kabeer Hospital (kuwait). The patients ranged from 27 to 56 years of age. Seven had a prior Caesarean section and one had a hysterectomy for fibroid. They presented 3-8 years later with nodules in/near the abdominal scar. Five cases presented with a painful nodule, fluctuant with the menstrual cycle. RESULTS: Cytological findings comprised epithelial clusters and fusiform stromal cells with numerous haemosiderin-laden macrophages. Mild to moderate epithelial atypia was observed in three cases. A diagnosis of endometriosis was rendered in all the eight cases and tissue was available in four cases. CONCLUSIONS: Endometriotic nodules need to be differentiated from other benign/malignant masses and evaluated for possible malignant transformation. FNAC provides a safe and effective tool for diagnosis thereby obviating the need for other procedures.
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ranking = 89.183437103002
keywords = menstrual cycle, cycle
(Clic here for more details about this article)

7/10. Extrapelvic endometriosis presenting as a hernia: clinical reports and review of the literature.

    endometriosis is a common gynecologic diagnosis. Typical complaints of patients with pelvic endometriosis include dysmenorrhea, menstrual irregularities, dyspareunia, and infertility. endometriosis may also occur in extrapelvic sites and cause unusual symptoms and diagnostic dilemmas. endometriosis has been described in the inguinal region, and this is illustrated in the first case history. The tender inguinal masses often fluctuate with the menstrual cycle but the condition initially may be confused with an inguinal hernia. Treatment is surgical. abdominal wall scar endometriosis, seen in the second case, has been described in patients after a wide variety of gynecologic procedures. This also is initially noted as a tender mass, usually fluctuating with menstruation, and is often confused with an incisional hernia. Again, surgery is the treatment of choice. Pathologic features of endometriosis are constant, regardless of location. Microscopically, endometrial glands and stroma, fibrosis, chronic inflammation, and old hemorrhage are seen. Familiarity with the unusual types of endometriosis is important to the general surgeon.
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ranking = 89.183437103002
keywords = menstrual cycle, cycle
(Clic here for more details about this article)

8/10. Two cases of endometrioma in cesarean scars.

    The occurrence of endometrioma in cesarean scar is an infrequent event usually presenting as a tender abdominal wall mass. Two cases are reported here. diagnosis is suggested when the symptoms are cyclic and associated with the patient's menstrual cycle, but this is not always the case. Surgical excision is the method of choice for diagnosing and ultimately treating the lesion.
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ranking = 89.183437103002
keywords = menstrual cycle, cycle
(Clic here for more details about this article)

9/10. Metastatic endometriosis in abdominal scars.

    The author presents two examples of metastatic endometriosis occurring in an abdominal scar. These case reports illustrate the two main theories of the pathogenesis of the condition: transportation and metaplasia. The diagnosis is straightforward in the classic case in which a painful mass fluctuates with the menstrual cycle, but a biopsy may be needed to confirm the diagnosis when the history is atypical. The treatment of choice, for those who require treatment, may be hormonal manipulation, surgery or irradiation, or a combination of these.
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ranking = 89.183437103002
keywords = menstrual cycle, cycle
(Clic here for more details about this article)

10/10. Accidental ovarian autograft after a laparoscopic surgery: case report.

    OBJECTIVE: To report an autograft of ovarian tissue in the incision of the surgical trocar during laparoscopic surgery and to assess the potentiality of grafting of ovarian parenchyma in nonpelvic tissue in humans. DESIGN: A case report. SETTING: Instituto de Fertilidad y Ginecologia de Buenos Aires (IFER), Buenos Aires, argentina. PATIENT(S): Infertile patient undergoing surgery due to an endometriotic cyst of the left ovary. INTERVENTION(S): Laparoscopic cystectomy. Accidental retention of a portion of the capsule and adjacent ovarian tissue of the endometrioma in SC cellular tissue. Months after surgery, a SC tumor was formed under the surgical incision. It was subsequently excised. MAIN OUTCOME MEASURE(S): observation of tumor growth during menstrual cycles and ovulation induction; anatomopathologic study of the tissue after its extirpation. RESULT(S): The tumor grew spontaneously in the periovulatory period and during treatments of ovulation induction. The anatomopathologic report of the tumor, removed 15 months after the first surgery, revealed functioning ovarian tissue with vessels of neoformation. CONCLUSION(S): This is the first description of autografted ovarian tissue in humans. We describe that the ovary can maintain its ovulatory function even in the absence of its pedicel. Also, we suggest that extirpation of surgical material through the incision of the trocar is not recommended, as the possibility of "sowing" or of autografts may occur.
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ranking = 89.183437103002
keywords = menstrual cycle, cycle
(Clic here for more details about this article)
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