Cases reported "Carcinoma in Situ"

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11/24. Squamous cell carcinoma in situ of the endometrium and fallopian tube as superficial extension of invasive cervical carcinoma.

    Five cases of squamous cell carcinoma of the cervix associated with widespread squamous cell carcinoma in situ of the endometrial surface are reported. In one case, carcinoma in situ was also found in one fallopian tube in continuity with the cervicoendometrial lesion. A survey of the literature reveals only 20 cases with similar surface endometrial involvement by cervical squamous cell carcinoma. Of these, the fallopian tubes were involved by an identical lesion in six cases only. pyometra and cervical stenosis were reported in about 66% of the cases. This rare form of upward cervical cancer extension was present in five of 680 cases (0.7%) of squamous cell carcinoma of the cervix in the file of the Tumor Registry of Magee-Womens Hospital.
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12/24. Obstructing fallopian tube papilloma.

    A grossly well-defined papilloma was found in the fallopian tube of a 41-year-old woman who had a total hysterectomy and bilateral salpingo-oophorectomy for carcinoma in situ of the cervix. The papilloma was unassociated with significant inflammation, hormone administration, or endogenous hormone excess. It presented as a hydrosalpinx developing over a period of several months. This may represent the second true fallopian tube papilloma to be recorded.
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13/24. female genital tract and peutz-jeghers syndrome: an immunohistochemical study.

    Systematic detection of endocrine cells was performed in two genital tracts from patients with peutz-jeghers syndrome (PJS). These tissues proved to be particularly rich in endocrine cells. The specialized cells were distributed in the cervix and fallopian tubes. In the cervix, they were confined to remarkable mucinous tumors related to "adenoma malignum." serotonin, somatostatin, gastrin, and pancreatic polypeptide immunoreactive cells were characterized. In fallopian tubes, serotonin-storing cells and somatostatin cells were detected respectively among normal-appearing and mucinous areas of tubal epithelium; in addition, serotonin-storing cells were found in many mesonephric rests. This strongly contrasts with the usual paucity of endocrine cells in the female genital tract. However, none of the findings mentioned was really specific of PJS. In particular, endocrine cells seem to be an integral constituent of adenoma malignum, with or without PJS. These findings suggest a disturbance of tissular differentiation.
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ranking = 0.16734891645038
keywords = fallopian tube, tube
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14/24. Squamous cell carcinoma in situ from the uterine cervix to the distal end of the fallopian tube.

    An unusual case of squamous cell carcinoma of the uterine cervix is described in which spread occurred intraepithelially along the endometrium and one of the fallopian tubes. This marked superficial extension is an example of abnormal spread of a malignant tumour whose prognostic significance is unknown.
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keywords = fallopian tube, tube
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15/24. The persistence of bacille Calmette-Guerin in the bladder after intravesical treatment for bladder cancer.

    OBJECTIVE: To determine the incidence of bacille Calmette-Guerin (BCG) bacilli persisting in the urinary tract of patients treated previously with intravesical BCG for carcinoma in situ or multiple Ta.T1 transitional cell carcinoma. patients AND methods: One-hundred and twenty-five patients were treated at the Freeman Hospital, Newcastle upon Tyne, UK over an 8-year period, 90 of whom submitted early morning urine samples for culture for acid-fast bacilli at varying intervals following BCG treatment. The records of all patients were reviewed to determine the incidence of caseating granulomata containing acid-fast bacilli together with the incidence of toxicity and the outcome of treatment. RESULTS: Five patients were found to have persisting acid-fast mycobacteria in their urine or bladder up to 16.5 months after completing intravesical instillations of BCG. In one patient this probably accounted for bladder symptoms that required palliative cystectomy. In four patients the 'infection' was not severe. Two patients were treated with antituberculous chemotherapy without complication. Three years after intravesical BCG therapy 36 of 69 patients (52%) had remained tumour free. CONCLUSION: BCG organisms can persist in the urinary tract for at least 16.5 months after the completion of intravesical BCG instillation therapy.
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ranking = 0.00068224978371089
keywords = tube
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16/24. Primary fallopian tube adenocarcinoma in situ associated with adjuvant tamoxifen therapy for breast carcinoma.

    We report the first case of primary fallopian tube adenocarcinoma in situ in a patient who had received antiestrogen tamoxifen as adjuvant therapy for breast carcinoma. Clinical and in vivo animal model studies, referable to the possible estrogen agonist effect of tamoxifen on the female genital tract, are also reviewed.
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ranking = 0.83333333333333
keywords = fallopian tube, tube
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17/24. Disseminated infection after intravesical BCG immunotherapy. Detection of organisms in pulmonary tissue.

    A 57-year-old man undergoing intravesical immunotherapy with BCG for transitional cell bladder carcinoma presented with dyspnea, fever, hypoxemia, and a diffuse micronodular pattern on chest radiograph. Transbronchial biopsy specimen revealed widespread noncaseating granulomas, and acid-fast bacilli were identified in sputum as well as in the biopsy tissue. The patient's condition responded promptly to antituberculous antibiotics given in conjunction with corticosteroids. Although no growth was evident on TB culture of the specimens, the presence of organisms indicates a probable infectious cause of the pulmonary disease process.
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ranking = 0.00068224978371089
keywords = tube
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18/24. Percutaneous mitomycin C perfusion of bilateral ureteral carcinoma in situ.

    We treated a 61-year-old patient with a diagnosis of bilateral ureteral carcinoma in situ with percutaneous perfusions of mitomycin C. After 16 sessions of mitomycin C therapy instilled through bilateral nephrostomy tubes, the urine cytology results became negative for malignancy. Bilateral ureteroscopy and cold-cup punch biopsies of the ureter revealed no evidence of disease. The patient did not experience side effects. He has remained free of disease during a 12-month follow-up period. Percutaneous perfusion of mitomycin C appears to be one of the effective and safe treatments for the carcinoma in situ of the upper urinary tract.
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ranking = 0.00068224978371089
keywords = tube
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19/24. Implant metastasis of gallbladder carcinoma in situ in a cholecystectomy scar: a case report.

    A subcutaneous mass within the scar left by cholecystectomy with common bile duct exploration and T-tube drainage developed 6 years after surgery. Pathologic examination of this mass showed features of atypical villous hyperplasia, similar to that identified within the previously removed gallbladder, but with additional foci of carcinoma in situ. Since excision of the mass, the patient has had persistent fluid collections requiring frequent aspiration. Cytologic analysis of the fluid has revealed tumor cells. The cause of this spread has been unclear. Few literature reports have identified biliary drainage techniques as a source for metastatic seeding. The malignant or metastatic potential of severe dysplasia or carcinoma in situ of the gallbladder associated with T-tube drainage and implantation in the drainage tract is previously unreported.
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ranking = 0.0013644995674218
keywords = tube
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20/24. Psammoma bodies and cells from in situ fallopian tube carcinoma in endometrial smears: a case report.

    BACKGROUND: Primary in situ fallopian tube carcinomas are rarely diagnosed, and malignant cells from this lesion have not been previously described as occurring in endometrial smears. CASE: A 57-year-old, postmenopausal woman had an endometrial smear that revealed adenocarcinoma cells associated with psammoma bodies. She also had smooth muscle cells in the smear compatible with uterine leiomyomas. Examination of the hysterectomy specimen disclosed a primary in situ carcinoma of the left fallopian tube and uterine leiomyomatosis. CONCLUSION: Endometrial cytology plays an important role in the diagnosis of pathologic processes in the uterus. It may also contribute useful information on extrauterine diseases.
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