1/28. Ten-year follow-up of mammary carcinoma arising in microglandular adenosis treated with breast conservation.adenosis is a rare proliferative lesion of the breast that may mimic carcinoma grossly and histologically. Although the lesion in its simplest form is benign, it can give rise to carcinoma, which may be found at the time of diagnosis in a minority of cases. Limited follow-up data have indicated no predisposition to develop subsequent carcinoma in patients treated with excisional biopsy for microglandular adenosis when carcinoma was not initially present. breast conservation has rarely been used in patients with carcinoma arising in microglandular adenosis. We report here the unique 10-year follow-up of a woman who underwent breast conservation treatment for carcinoma that arose in microglandular adenosis.- - - - - - - - - - ranking = 1keywords = gland (Clic here for more details about this article) |
2/28. Synchronous bilateral noninvasive ductal carcinoma of the male breast: a case report.A 45-year-old man developed a bloody discharge from his right nipple. physical examination revealed bloody discharge from his left nipple also but no swelling, breast mass, or axillary lymph nodes. He then underwent bilateral total glandectomy without axillary dissection. Histological examination revealed low-grade ductal carcinoma in situ (DCIS) with a low-papillary and cribriform pattern measuring about 4 mm in diameter in the breast bilaterally. To our knowledge, this is the first report of synchronous bilateral DCIS in a male. Since this patient's hormonal profile showed a relatively high blood level of prolactin, the causative relationship between hyperprolactinemia and male breast cancer is discussed. Including our case, 5 of 6 cases reported thus far have been bilateral, and 4 of the 6 cases have been synchronous. We emphasize that the contralateral breast should also be tested or followed in male breast cancer patients with hyperprolactinemia.- - - - - - - - - - ranking = 0.14285714285714keywords = gland (Clic here for more details about this article) |
3/28. Intraductal carcinoma of major salivary gland.The clinicopathologic features of the cases of three patients with intraductal carcinoma of major salivary gland are described. As in the breast, these lesions of salivary ducts appear to represent an in situ or preinvasive phase of the disease. On follow-up, one patient had a local recurrence, and in another patient, the tumor subsequently became invasive. This experience suggests that wide surgical excision (preferably total parotidectomy) may be curative but that resections limited to grossly visible disease will result in local recurrence and/or the development of invasive ductal adenocarcinoma.- - - - - - - - - - ranking = 0.71428571428571keywords = gland (Clic here for more details about this article) |
4/28. carcinosarcoma of the submandibular salivary gland. Immunohistochemical findings.Carcinosarcomas of the salivary glands are rare lesions that generally have been associated with benign mixed tumors. The authors report a case of a submandibular gland lesion, which occurred in a 64-year-old man, that was composed of intermingled ductal type adenocarcinoma and osteogenic sarcoma with a large component of osteoclast-like giant cells. The local recurrence of the tumor was entirely sarcomatous with no epithelial component observed. There was no histologic evidence of a preexisting or coexisting pleomorphic adenoma. Immunohistochemical studies confirmed two separate populations of tumor cells, corresponding to the histologic growth pattern. The authors review the literature and discuss histogenetic implications of distinction between de novo carcinosarcoma and carcinosarcoma in association with pleomorphic adenoma.- - - - - - - - - - ranking = 0.85714285714286keywords = gland (Clic here for more details about this article) |
5/28. Sweat gland carcinoma with mucinous and infiltrating duct-like patterns.We report a rare case of mucinous carcinoma of the skin with mammary infiltrating carcinoma-like patterns. An 82-year-old Japanese male had a gourd-shaped tumor on his scalp. Histopathologically, the posterior portion of the tumor showed small lobules of cuboidal tumor cells with no atypia floating in mucinous lakes. In the anterior portion, there were solid lobules, cords, and strands of anaplastic tumor cells infiltrating into the surrounding stroma. Enzyme- and immunohistochemistry and electron microscopy confirmed the eccrine origin of this tumor. It is suggested that mucinous carcinoma of the skin can occur in association with diverse histological patterns, analogous to mucinous carcinoma of the breast.- - - - - - - - - - ranking = 0.57142857142857keywords = gland (Clic here for more details about this article) |
6/28. Intraductal papillary carcinoma of bilateral breasts: a case report.We report a 59-year-old woman presenting with a 2-month history of occasional bloody discharge from her right nipple and a palpable right breast mass on self-examination. The mammography revealed heterogeneously dense fibroglandular stromas of bilateral breasts, a lobulated mass in her right breast associated with faint pleomorphic microcalcifications, and, in addition, very faint focal granular microcalcifications in the left breast. breast ultrasound revealed a lobulated and heterogeneous hypoechoic tumor with irregular margins at the right breast and a well-circumscribed tumor with heterogeneous echotexture at the left breast.- - - - - - - - - - ranking = 0.14285714285714keywords = gland (Clic here for more details about this article) |
7/28. Mammary gland anatomy and the role of mammography and ultrasonography in the early diagnostics of breast cancer. A case report.Progress in imaging techniques has brought a solution to the problem of the early diagnosis of breast cancer. An interesting case of breast cancer is presented here, pictures of the malignant tumour are demonstrated and the usefulness of new diagnostic methods analysed. The presentation of this case may contribute to greater effectiveness in early breast cancer detection.- - - - - - - - - - ranking = 0.57142857142857keywords = gland (Clic here for more details about this article) |
8/28. Intraductal carcinoma of the tongue. Report of a case.A case of intraductal carcinoma arising from a minor salivary gland of the tongue is reported. The relevant literature is discussed.- - - - - - - - - - ranking = 0.14285714285714keywords = gland (Clic here for more details about this article) |
9/28. Ductal carcinoma in situ of the breast with osteoclast-like giant cells.Mammary carcinoma with multinucleated osteoclast-like giant cells (OGCs) is a rare, distinctive variant of breast carcinoma. To date, all of these instances have been described as part of an invasive carcinoma. Here, we report a case of ductal carcinoma in situ of the breast with numerous admixed OGCs present within gland lumens without an associated invasive component. Similar to invasive carcinomas with OGCs, both the in situ carcinoma and the OGCs exhibited overexpression for vascular endothelial growth factor. This case expands the spectrum of tumors associated with OGCs and provides further evidence for the possible role of vascular endothelial growth factor in the stromal-epithelial interactions of in situ mammary carcinoma.- - - - - - - - - - ranking = 0.14285714285714keywords = gland (Clic here for more details about this article) |
10/28. Intraductal carcinoma of mammary-type apocrine epithelium arising within a papillary hydradenoma of the vulva. Report of a case and review of the literature.We report and immunohistochemically document the first (to the best of our knowledge) case of malignancy in which an intraductal carcinoma resembling apocrine breast cancer arose within a papillary hidradenoma of the vulva. Papillary hidradenoma is generally thought to originate from apocrine sweat glands, but a derivation from milk line remnants of the vulva should also be considered. Immunoreactivities for low- and high-molecular-weight cytokeratins, alpha-smooth-muscle-specific actin, carcinoembryonic antigen, S100 protein, and gross cytic disease fluid protein 15, an antigen of apocrine differentiation, show features that resemble those of an intraductal apocrine breast cancer. Positivity for gross cystic disease fluid protein 15 as well as the presence of estrogen and progesterone receptors suggest that tumor cells are controlled by ovarian steroid hormones. To our knowledge, no cases of malignancy arising from a papillary hidradenoma have been proved to date. Therefore, we also discuss previously reported cases of putative cancers that have developed in papillary hidradenomas. In the case presented herein, a local excision with a narrow rim of surrounding tissue was performed, and the patient was alive and well, without signs of recurrence, after 2 years of follow-up.- - - - - - - - - - ranking = 0.14285714285714keywords = gland (Clic here for more details about this article) |
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