1/26. Cholinsalicylate gel induced oral lesion: report of case.salicylic acid and its derivatives are extensively used medications for the treatment of systemic and local diseases. However, injudicious use of aspirin as well as other derivatives of salicylic acid, may cause systemic and oral complications such as mucosal burns and oral ulcers. In children, topical administration of these drugs, even in small dosages, may cause adverse reactions. This report shows a case of an 8 year old boy with G6PD deficiency, who had a mucosal burn caused by application of a cholinsalicylate paste. Three days later, the child developed oral ulcers, malaise and fever. The present case is characteristic of the enigmatic nature of the etiology and diagnosis of oral lesions, and the possible connection between cholinsalicylate systemic absorption and hemolytic anemia is discussed.- - - - - - - - - - ranking = 1keywords = drug (Clic here for more details about this article) |
2/26. Clinitest burns of the esophagus.Five children developed esophageal stricture from the ingestion of a Clinitest tablet. The sodium hydroxide contained in these tablets induced a short, dense stricture that was resistant to dilation and necessitated resection. In all patients primary esophageal resection with end-to-end anastomosis was technically possible. Four of the patients needed two or more dilations postoperatively and 1 still requires dilation. Prevention of accidental ingestion by use of a childproof container and parental education about the caustic nature of Clinitest are both essential to eliminate this child health hazard.- - - - - - - - - - ranking = 268646.84283694keywords = container (Clic here for more details about this article) |
3/26. burns caused by dilute hydrofluoric acid in the bleach.Two male cleaning workers aged 62 (patient 1) and 28-(patient 2) presented with red, swollen, aching hands and fingers. At the first interview, the fingers of the right hand of both patients were swollen from the proximal interphalangeal joint to the tip of the finger. The fingers were red and intensely painful. The bleach that both patients used contained 9.5% hydrofluoric acid, and therefore we diagnosed their symptoms as those of burns caused by this agent. We subcutaneously injected 8.5% calcium gluconate into the affected fingers and dressed them with gauze soaked in cooled 0.025% benzethonium chloride. The patients did not use gloves at work, neither of them knew that the cleaning fluid contained dilute hydrofluoric acid, and they were unaware of the danger of this agent. They had not received proper education about the care and handling of poisons and deleterious substances such as hydrofluoric acid. The doctors who had examined the patients in the emergency ward overlooked the possibility of hydrofluoric acid burns, although they suspected chemical burns and confirmed the trade name of the cleaning agent. In addition, although the patients presented with intense pain, no white areas of coagulation and blistering, or surrounding erythemas, which are characteristic symptoms of such burns, were evident. The component of the cleaning agent was described on the container label in very small print. Had the words "poison" and "hydrogen fluoride" been printed in large characters, the examining doctors in the emergency ward would probably not have overlooked the presence of hydrofluoric acid, and the patients would perhaps have been more careful when using it. hydrofluoric acid can be easily obtained by anyone through the internet, although general consumers could not obtain industrial quantities. Therefore, the number of burn patients who are not familiar with hydrofluoric acid may increase in the future.- - - - - - - - - - ranking = 268646.84283694keywords = container (Clic here for more details about this article) |
4/26. Benzalkonium chloride poisoning in infant twins.infant twins sustained severe circumoral and pharyngeal burns from a concentrated solution of benzalkonium (Zephiran) chloride prescribed for treatment of candidiasis. This report emphasizes the unnecessary hazard accompanying use of a potentially toxic drug-especially when prepared in error by the pharmacist-when a safer drug (nystatin) is available for treatment of oral candidiasis. Risks from use of a prescription drug for other than the intended patient are also highlighted by this episode of poisoning.- - - - - - - - - - ranking = 3keywords = drug (Clic here for more details about this article) |
5/26. Desiccant-induced gastrointestinal burns in a child.Desiccants are commonly composed of non-toxic chemicals such as silica gel. A 2-y-old male unintentionally ingested the contents of a desiccant packet found in a container of imported Chinese cookies. He presented with vomiting, drooling and inability to drink. A caustic injury to his tongue and phaynx was noted. He improved over the next 12 h and was discharged a day later. The packet was found to contain caustic lime Although patients who ingest desiccant packets generally develop no clinical effects, ingestion of packets containing strong alkali may prove consequential. Providers should be aware of the potential for this toxicity before dismissing desiccant exposures as benign.- - - - - - - - - - ranking = 268646.84283694keywords = container (Clic here for more details about this article) |
6/26. The relationship of burn wound fluid to serum creatinine and creatinine clearance.A case is presented with emphasis on creatinine clearance and burn wound closure. It suggests that the burn wound acts as an extrarenal site for creatinine loss. As a result, renal creatinine clearance may be falsely elevated while the burn wound is open, and closure of the burn wound may affect creatinine clearance.- - - - - - - - - - ranking = 3.9836956398181keywords = closure (Clic here for more details about this article) |
7/26. A near fatal case of corrosive burns from decomposed chloral hydrate administration.A case of corrosive burns to the face and upper airway from administration of chloral hydrate is presented. Events leading to the accident and dispensing of the drug are discussed.- - - - - - - - - - ranking = 1keywords = drug (Clic here for more details about this article) |
8/26. Pediatric caustic ingestion and parental cocaine abuse.OBJECTIVE: To report two cases in which toddlers drank a caustic liquid which their parents had been using to prepare free-base and crack cocaine. DESIGN: Case series. RESULTS: Two toddlers presented with first- and second-degree burns of the oral cavity, pharynx and esophagus from caustic ingestion. The first had drunk ammonia from an unmarked clear plastic container the morning after "a party at a friend's house". The second had drunk potassium hydroxide from a clear plastic container which was labelled "pH UP" and had a small "Danger" sign. Both children were treated with intravenous hydration, steroids, antibiotics and analgesics. Fortunately, neither child suffered long-term physical sequelae. When questioned, the parents of both children admitted to using these alkalis to prepare free-base and crack cocaine. Appropriate steps were taken by social services to protect these children from further neglect. DISCUSSION: Despite federal legislation and public education, pediatric caustic ingestion remains a significant problem. These cases suggest that, in certain cases of pediatric caustic ingestion, caregivers should be questioned regarding possible drug abuse. Larger warning labels and further public education might help prevent many cases of pediatric caustic ingestion.- - - - - - - - - - ranking = 537294.68567387keywords = container, drug (Clic here for more details about this article) |
9/26. Case study: flame arresters and exploding gasoline containers.This paper describes the case study of a portable plastic gasoline container explosion and fire. While working at home on a science project to determine the burn rates of different types of wood fuel, a 14-year-old boy was severely burned after flames traveled back up into the portable gasoline container and exploded. A witness heard the explosion and reports that the flames went perhaps 10 ft in the air. It is shown by experimentation that a flame arrester installed in the pour opening of the portable gasoline container would have prevented an explosion inside the gasoline container.- - - - - - - - - - ranking = 2149174.7426955keywords = container (Clic here for more details about this article) |
10/26. Severe esophageal burn following chloral hydrate overdose in an infant.chloral hydrate is generally considered to be a safe hypnotic drug, and is commonly used for short-term sedation before diagnostic procedures. Its irritant actions to the mucous membranes are usually limited. We report a rare complication of chloral hydrate overdose in an infant. An 8-month-old male infant became unconscious and required ventilation support after an overdose of chloral hydrate was administered to provide sedation for an ophthalmologic examination. White plaques and sloughing of the oropharyngeal mucosa were observed on the next day. Esophagogastroscopy revealed severe corrosive lesions on the whole esophagus. The child recovered after supportive treatment and his oral intake remained well without dysphagia after 1 year. This report illustrates the potential corrosive effect of chloral hydrate. Strict attention should be paid to the dosing and administration protocol of chloral hydrate in infants. The condition of the oropharyngeal mucosa should be carefully monitored after chloral hydrate administration.- - - - - - - - - - ranking = 1keywords = drug (Clic here for more details about this article) |
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