1/43. Posthaemorrhagic iron deficiency. Clinical course, 59Fe whole-body iron losses, and oral iron supplementation.Clinical and laboratory data characterizing post-haemorrhagic anaemia with still normal iron stores and posthaemorrhagic iron deficiency in the manifest, latent or prelatent stage are presented. Initially, increased 59Fe whole-body iron losses (greater than 0.1-3.6%/day) returned to normal range (less than 0.1%/day) after haemostasis. Subsequently, slow increase of haemoglobin and repletion of iron stores occurred under normal diets. Manifest, latent, and prelatent iron deficiencies were corrected much more rapidly by total doses of 12.0, 10.5 and 8.0 g iron (Fe2 sulfate), respectively, when 2 X 50 mg/day were given in quick-release capsules apart from meals.- - - - - - - - - - ranking = 1keywords = anaemia (Clic here for more details about this article) |
2/43. Isoimmune haemolysis in pathogenesis of anaemia after cardiac surgery.A patient who had received multiple transfusions developed antiglobulin-positive haemolytic anaemia due to a delayed haemolytic transfusion reaction. Many cases of haemolytic anaemia after cardiac surgery could be explained on this basis.- - - - - - - - - - ranking = 6keywords = anaemia (Clic here for more details about this article) |
3/43. Surdocardiac syndrome of Jervell and Lange-Nielsen, with prolonged QT interval present at birth, and severe anaemia and syncopal attacks in childhood.A case of the surdocardiac syndrome of Jervell and Lange-Nielsen, with prolonged QT interval in the electrocardiogram at birth, is described. The affected girl presented 3 1/2 years later with severe iron deficiency anaemia, despite apparently adequate nutrition. At the age of 4 1/2 years she had a sudden attack of unconsciousness. Treatment with the beta-adrenoceptor blocker practolol was started and 3 years after initiation of this treatment she has been free from syncopal attacks. The QT interval remains prolonged. Her brother also had severe iron deficiency anaemia and had several attacks of unconsciousness before he died suddenly at the age of 3 1/2 years.- - - - - - - - - - ranking = 6keywords = anaemia (Clic here for more details about this article) |
4/43. Severe anaemia and ileocolic anastomotic ulceration.Two children are described with anaemia from ileocolic anastomosic ulceration as a late complication of surgery in the newborn period. The anastomosis was revised in each case but in one child there was early recurrence of ulceration.- - - - - - - - - - ranking = 5keywords = anaemia (Clic here for more details about this article) |
5/43. Antral vascular ectasia: the watermelon stomach.Antral vascular ectasia (watermelon stomach) is an uncommon localised vascular abnormality which may cause occult gastrointestinal blood loss and iron deficiency anaemia. The endoscopic appearances are characteristic with well demarcated, often raised or nodular bright red streaks radiating from the pylorus back along the antrum. Endoscopic biopsies can be taken without risk of haemorrhage and may help distinguish this condition from gastritis. The aetiology remains obscure, but there is an association with achlorhydria, hypergastrinaemia, and cirrhosis of the liver. Four patients are described; two had antrectomy with long term control of their anaemia, and two were treated conservatively. The lesion may be diagnosed more frequently with more widespread recognition of the condition.- - - - - - - - - - ranking = 2keywords = anaemia (Clic here for more details about this article) |
6/43. Remission of transfusion-dependent myelodysplastic syndrome in association with respiratory tract infection.We describe a case of blood transfusion-dependent myelodysplastic syndrome (refractory anaemia), associated with macrocytosis and elevated percentage of hypochromic cells. Following an acute hospital admission with a respiratory tract infection, the patient entered a complete and sustained remission.- - - - - - - - - - ranking = 1keywords = anaemia (Clic here for more details about this article) |
7/43. Systemic consequences of non-healing skin wounds: anaemia of chronic disease.The paper describes a case of skin wounds inflicted by automutilation in a young woman with psychic regulation disorder. Repeated local irritation and infection produced a complicated systemic disorder leading to hypochromic anaemia which failed to respond to Fe treatment. The paper discusses the mechanism of this type of anaemia which appears in literature under the heading of anaemia of chronic disease (ACD).- - - - - - - - - - ranking = 7keywords = anaemia (Clic here for more details about this article) |
8/43. The potential pitfall of attributing iron deficiency anaemia to ulceration in a Barrett's oesophagus.We report a 58-year-old man with recurrent ulceration in a Barrett's oesophagus whose iron-deficiency anaemia was in fact due to a caecal carcinoma. Recent reports suggest an association between these two disorders. A Barrett's oesophagus should not be blamed for iron deficiency unless neoplasms of the colon have been excluded.- - - - - - - - - - ranking = 5keywords = anaemia (Clic here for more details about this article) |
9/43. pica and iron-deficiency anaemia.In two cases of children with pica referred to a child psychiatrist, both were found to have undiagnosed iron-deficiency anaemia. Treatment with iron supplements and dietary advice led to decrease or cessation of pica.- - - - - - - - - - ranking = 5keywords = anaemia (Clic here for more details about this article) |
10/43. Syncopes leading to the diagnosis of a helicobacter pylori positive chronic active haemorrhagic gastritis.A 15-year-old girl was admitted after 1 week of increasing fatigue and pallor. She had no gastro-intestinal complaints. The patient had suffered from four episodes of syncope during the last 3 days prior to admission. Besides pallor and a discrete cardiac murmur, the physical examination was normal. A further thorough investigation revealed an iron deficiency anaemia related to a helicobacter pylori positive chronic active haemorrhagic gastritis. Treatment consisted of amoxycillin and colloidal bismuth subcitrate (500 mg and 120 mg orally respectively, 3 times daily) during a period of 6 weeks. iron supplements were not administered. Together with the clearance of H. pylori and healing of the haemorrhagic gastritis, as demonstrated by histology, haemoglobin values returned to normal and the symptoms disappeared. An eradication of the micro-organism was obtained. She has since had no further similar complaints.- - - - - - - - - - ranking = 1keywords = anaemia (Clic here for more details about this article) |
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