1/12. Odontoameloblastoma: report of a case.Odontoameloblastoma is a very rare odontogenic tumour that is similar to ameloblastoma in its locally aggressive behaviour. Its clinical presentation, however, often mimics the more innocuous odontoma, and hence the recognition of its aggressive nature is commonly only ascertained after its histopathologic diagnosis following enucleation. This paper presents a case of odontoameloblastoma. Some of the difficulties that may be encountered in the diagnosis and treatment planning of odontoameloblastomas are discussed.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
2/12. ameloblastoma of the jaws.ameloblastoma is a histologically benign tumor derived from odontogenic apparatus. The tumor can infiltrate into surrounding tissues. Although it is benign, it presents symptoms of a malignant tumor, such as infiltration into the lungs, pleura, regional and distant metastases, orbit, base of skull, brain and has resulted in death. It also has a high incidence of recurrences, the existence of regional or distant metastasis, showing a microscopic pattern of ameloblastic carcinoma with cytologic features of an increasing nuclear/cytoplastic ratio, nuclear hyperchromatism, and the presence of mitosis. We report a study of 12 patients of ameloblastoma of the jaws between January 1992 and December 1996 consisting of 8 affected in the mandible and 4 in the maxilla. One patient with a tumor in the maxilla was excluded from this study, due to a different histological and clinical behaviour of the ameloblastoma.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
3/12. Ameloblastic carcinoma: case report and literature review.Ameloblastic carcinoma is a rare malignant lesion with characteristic histologic features and behaviour that dictates a more aggressive surgical approach than that of a simple ameloblastoma. However, reliable evidence of its biologic activity is currently unavailable due to the scarcity of well-documented cases. It occurs primarily in the mandible in a wide range of age groups; no sex or race predilection has been noted. It may present as a cystic lesion with benign clinical features or as a large tissue mass with ulceration, significant bone resorption and tooth mobility. Because the lesion is usually found unexpectedly after an incisional biopsy or the removal of a cyst, a guide to differential diagnosis is not usually useful. The identifying features of ameloblastic carcinoma must be known and recognized by dental practitioners. Our understanding of the histologic features of ameloblastic carcinoma is somewhat vague. The tumour cells resemble the cells seen in ameloblastoma, but they show cytologic atypia. Moreover, they lack the characteristic arrangement seen in ameloblastoma. The clinical course of ameloblastic carcinoma is typically aggressive, with extensive local destruction. Direct extension of the tumour, lymph node involvement and metastasis to various sites (frequently the lung) have been reported. Wide local excision is the treatment of choice. Regional lymph node dissection should be considered and performed selectively. radiotherapy and chemotherapy seem to be of limited value for the treatment of ameloblastic carcinomas. At the moment, there are too few reported cases to make a definite recommendation regarding treatment. Close periodic reassessment of the patient is mandatory.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
4/12. Clinical and radiologic behaviour of ameloblastoma in 4 cases.ameloblastoma is a benign but locally aggressive epithelial odontogenic neoplasm. It represents 1% of all tumours of the jaw bone. In 80% of cases, it is localized in the mandibular molar and ascending ramus area, mostly associated with an unerupted tooth. It occurs over a wide range of ages (mean age is in the 20s or 30s) and with equal frequency in men and women.ameloblastoma may be discovered during a routine radiographic examination or as a clinically observed developing mass. It has a characteristic, but not diagnostic, radiographic appearance. It can be treated by enucleation, bone curettage or wide resection. The rate of local recurrence is high when it is treated inadequately.We describe the clinical and radiologic behaviour of ameloblastoma and discuss treatment protocols and the possibility of conservative management of this tumour. Our results suggest the importance of long-term follow-up with various radiographic techniques.- - - - - - - - - - ranking = 5keywords = behaviour (Clic here for more details about this article) |
5/12. Calcifying and keratinizing ameloblastoma of the maxilla.A case is described of ameloblastoma of maxilla presenting with numerous calcified keratin pearls. The significance of cellular variation in relation to the behavioural potential of the ameloblastoma in general is briefly discussed.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
6/12. Aggressive calcifying odontogenic cyst--a possible variant of ameloblastoma.A case of an aggressive calcifying odontogenic cyst of the maxilla is presented. It recurred twice after surgical excision over the course of a year and was subsequently treated by maxillectomy followed by radiotherapy. The current histological criteria for the diagnosis of calcifying odontogenic cyst were satisfied but it is argued that they are drawn too widely. Since the majority of calcifying odontogenic cysts are benign in behaviour the presence of cytological indicators of local destruction and invasiveness alongside the usual features of calcifying odontogenic cysts (presence of dentinoid, epithelial ghost-cell degeneration) should be the over-riding prognostic considerations and should thus be reflected in the diagnostic title. Such tumours are best regarded as variants of ameloblastoma rather than as unusually aggressive forms of calcifying odontogenic cyst and an appropriate name would be 'dentinogenic ghost-cell ameloblastoma'.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
7/12. The recalcitrant keratocyst.The clinical enigma of appropriate management of the odontogenic keratocyst is a continuing controversy. The understanding of the pathology of the lesion has undergone a significant metamorphosis over the past 30 years. Certain research findings with respect to this lesion have set it apart from the classical odontogenic cyst, while histologic and clinical observations have made its behaviour reminiscent of the ameloblastoma. Despite its benign nature, its high recurrence rate begs the question of adequacy of treatment modalities to date. Fascinating theories have been put forward to account for its apparent resistance to conventional cyst therapy. Despite this, however, there is no unanimity as to pathogenesis or correct treatment methods. The case of a large odontogenic keratocyst of the mandible is reported and a detailed narrative of its apparently successful management by relatively conservative means is documented.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
8/12. An unusual case of adamantinoma of long bones.adamantinoma of the tibia is a rare bone lesion, in which it is impossible to predict the biological behaviour. A case of extremely late local recurrence and lung metastasis is presented. Additionally, the patient developed pneumothorax on the right side months before intrapulmonary metastasis could be detected by X ray. Finally 1 week before her death the young woman suffered from paraneoplastic severe hypercalcemia leading to hypercalcemic coma and pancreatitis.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
9/12. ameloblastoma of attached gingiva.A case of a rare extra-osseous ameloblastoma is presented. It meets identical histological criteria as intra-osseous ameloblastoma, but its clinical presentation and behaviour are very different. It is non-invasive and may be locally excised without recurrence.- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
10/12. Granular cell ameloblastoma: a case report with histochemical findings.A case of granular cell ameloblastoma (GCA) was studied by light microscopy and histochemistry. Microscopically, the lesion showed small groups or large clusters of granular neoplastic cells, with pyknotic and hyperchromatic nuclei, oriented away from the basement membrane, in a back-to-back arrangement. The "granular change" is thought to be due to a dysfunctional status of neoplastic cells, and the pathogenesis of this tumour seems to be age-related. The prognosis of GCA is good, generally corresponding to that of the classical ameloblastoma; as yet, only one case has been described with a more aggressive biological behaviour (high recurrence rate).- - - - - - - - - - ranking = 1keywords = behaviour (Clic here for more details about this article) |
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