Complex pain syndrome with unknown etiology, characterized by constant or intermittent generalized vulva pain (Generalized vulvodynia) or localized burning sensations in the VESTIBULE area when pressure is applied (Vestibulodynia, or vulvar vestibulitis syndrome). Typically, vulvar tissue with vulvodynia appears normal without infection or skin disease. vulvodynia impacts negatively on a woman's quality of life as it interferes with sexual and daily activities.