1/14. indocyanine green iris angiography of lung carcinoma metastatic to the iris.BACKGROUND: To investigate the usefulness of indocyanine green (ICG) iris angiography for monitoring vascular abnormalities and the clinical course of metastatic iris tumor during chemotherapy. methods: We performed ICG iris angiography at several points during systemic chemotherapy for a 67-year-old man who had been diagnosed as having small-cell carcinoma of the lung with metastatic iris tumors. RESULTS: ICG iris angiography clearly demonstrated hyperfluorescent tumor vessels, rubeosis iridis, and dilated iris stromal vessels. After chemotherapy, these hyperfluorescent vessels and rubeosis regressed. CONCLUSION: ICG iris angiography appears to be an effective and useful method for observing abnormal vessels associated with metastatic iris tumors.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
2/14. leiomyoma of the ciliary body. Report of 2 cases.PURPOSE AND methods: The files of the eye pathology Institute contain only two cases of leiomyoma of the ciliary body. The diagnoses were re-evaluated, applying modern immunostainings. RESULTS: The tumors were composed of interlacing fascicles of spindle-shaped cells with bright eosinophilic cytoplasm and cigar-shaped nuclei. Both tumors were well-vascularized, mostly by thin, branching capillaries. Larger vessels were also seen. In one case the tumor perforated the sclera. The tumor cells reacted with the reticulum stain and the Masson trichrome and were positive for antibodies against: smooth muscle actin (SMA), muscle specific actin (MSA), laminin and vimentin (one case). CONCLUSION: leiomyoma of the ciliary body is a rare smooth muscle cell tumor that may arise from either pericytes, ciliary - or intrascleral heterotopic muscle.- - - - - - - - - - ranking = 0.25keywords = vessel (Clic here for more details about this article) |
3/14. iris and ciliary body melanomas: ultrasound biomicroscopy with histopathologic correlation.OBJECTIVE: To correlate ultrasound biomicroscopic images of iris and ciliary body melanomas with their histopathologic features. methods: Ultrasound biomicroscopy was performed in 3 cases of iris melanoma and in 3 cases of ciliary body melanoma. Cross-sectional ultrasound biomicroscopic images were compared with findings from clinical examination and light microscopy to evaluate associations between their histopathologic, surface, and internal ultrasound characteristics. Unique images of intrastomal and obscured posterior tumor margins were visualized by ultrasound biomicroscopy. RESULTS: Results of this study revealed that ultrasound biomicroscopy offers an accurate method to evaluate tumor shape, reflectivity, and local invasion. Neoplastic tissue had only medium echogenicity. Enlarged vessels were correlated to echolucent spaces in the iris stroma. Anterior tumor margins were found within the iris stroma, within the anterior chamber angle, and on the endothelial surface of the cornea. Posterior tumor extension was noted to encroach onto the lens, into the sclera, and serous peripheral retinal detachments were associated with ciliary body tumors. CONCLUSION: Ultrasound biomicroscopic images correlated well with histopathologic features of anterior uveal melanomas including shape, reflectivity, and local extension. Arch Ophthalmol. 2000;118:1515-1521- - - - - - - - - - ranking = 0.25keywords = vessel (Clic here for more details about this article) |
4/14. Angioleiomyoma of the ciliary body: a case report.PURPOSE: To report a rare case of angioleiomyoma of the ciliary body methods: The clinical manifestation, imaging findings, histopathologic characteristics were analyzed in a 32-year-old male patient with angioleiomyoma of the ciliary body. RESULTS: The tumor was removed intact with local resection. Histopathologic examination revealed that the tumor was full of vessels and it was composed of spindle cells with abundant cytoplasm. Immunohistochemical studies showed positive for SMA and desmin and negative for S100 and HMB-45. CONCLUSIONS: Angioleiomyoma of the ciliary body is a rare tumor that can be successfully treated with local surgical resection in this area. It needs to be differentiated from other tumors, especially malignant melanoma.- - - - - - - - - - ranking = 0.25keywords = vessel (Clic here for more details about this article) |
5/14. Two discrete uveal melanomas in a child with ocular melanocytosis.OBJECTIVE: To describe a case of two uveal melanomas in a child with mild ocular melanocytosis. methods: A 6-year-old girl was followed for 5 years with an ill-defined, slowly enlarging presumed choroidal nevus in the postequatorial fundus. Ocular oncology evaluation revealed mild sectorial scleral and uveal melanocytosis and an episcleral sentinel vessel superotemporally. Two discrete uveal melanomas were present. In the circumpapillary and macular region, tumor 1 was diffuse at 9.0 mm in base and 4.1 mm in thickness and with overlying subretinal fluid. In the ciliary body, tumor 2 was discovered by transillumination and was 6.0 mm in base and 2.2 mm in thickness. Enucleation was performed. RESULTS: Histopathologic analysis disclosed two discrete uveal melanomas in a bed of diffuse mild uveal melanocytosis. Tumor 1 was a mixed, predominantly epithelioid cell melanoma with active mitotic figures, and tumor 2 was a mixed, predominantly spindle cell melanoma. The choroid between the melanomas showed only benign, dendritic melanocytes consistent with melanocytosis. There was no extrascleral extension. CONCLUSIONS: Ocular melanocytosis can predispose to one or multiple uveal melanomas. Lifetime ophthalmic monitoring of affected patients is warranted.- - - - - - - - - - ranking = 0.25keywords = vessel (Clic here for more details about this article) |
6/14. iris microhemangiomas.iris microhemangiomas (IM) are benign proliferations of small, twisted blood vessels along the pupillary margin. They are usually bilateral and appear to be developmental in nature. IMs most commonly occur in patients with myotonic dystrophy and adult-onset diabetes mellitus, but have also been associated with respiratory disease, congential heart disease, and central retinal vein occlusion. Additionally, they may be found in individuals without obvious ocular or systemic abnormality. The etiology remains obscure. In this report, illustrative cases are followed by a brief discussion outlining typical clinical manifestations, etiological considerations, and possible implications.- - - - - - - - - - ranking = 0.25keywords = vessel (Clic here for more details about this article) |
7/14. Anterior uveal neurilemmoma--a rare neoplasm simulating malignant melanoma.A 30-year-old woman presented with dilated episcleral vessels in the right eye which were found to be associated with an underlying ciliary body tumour. Contact lens examination, transpupillary transillumination, ultrasonography, computerised tomography, magnetic resonance imaging, and fine needle aspiration biopsy produced apparently conflicting and inconclusive results, and the eye was enucleated. light and electron microscopy showed the lesion to be a neurilemmoma (schwannoma), of which very few cases have been reported. The clinical and pathological features are described and discussed.- - - - - - - - - - ranking = 0.25keywords = vessel (Clic here for more details about this article) |
8/14. Neovascular glaucoma associated with an iris melanoma. A clinicopathologic report.A 48-year-old man had uniocular neovascular glaucoma, with the only apparent predisposing factor being a primary epithelioid melanoma of the iris. The new vessels disappeared following total excision of the tumor. These findings have implications regarding the mechanisms of neovasculogenesis.- - - - - - - - - - ranking = 0.25keywords = vessel (Clic here for more details about this article) |
9/14. light microscopic and electron microscopic histopathology of an iris microhaemangioma.A patient who had been observed to have an iris microhaemangioma (capillary haemangioma), confirmed on fluorescein iris angiography, came to cataract surgery. The lesion was excised at the time of surgery and submitted to light and electron microscopic study. It had the features of a hamartoma of the capillary haemangioma type, with its characteristics being specific for vessels seen in iris tissue.- - - - - - - - - - ranking = 0.25keywords = vessel (Clic here for more details about this article) |
10/14. argon laser treatment of an abnormal angle vessel producing recurrent hyphema.Spontaneous hyphema has been linked to many conditions. We describe a patient with recurrent spontaneous hyphema caused by an abnormal angle vessel without associated rubeosis iridis, glaucoma, or other vascular abnormalities as documented by iris fluorescein angiography. After treatment with several sessions of argon laser photocoagulation, the patient has remained asymptomatic during ten months of follow-up.- - - - - - - - - - ranking = 1.25keywords = vessel (Clic here for more details about this article) |
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