Cases reported "Syphilis, Cardiovascular"

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1/4. Accelerated atherosclerosis in tertiary syphilis and successful treatment with saphenous vein grafting--a case report.

    A 48-year-old male patient having none of the known risk factors for atherosclerosis underwent coronary artery bypass graft (CABG) surgery because of double-vessel coronary artery disease. During the operation, the aorta, both internal thoracic arteries (L/R-ITA), and the femoral artery were sclerotic, and CABG was performed using only saphenous vein grafts. A diagnosis of tertiary syphilis had been confirmed by either microscopic or serologic tests. There were different degrees of sclerosis in different arteries of different sizes. The presence of coronary artery disease with no known atherosclerotic risk factors should include preoperative testing for connective tissue disorders, chronic inflammatory disease, and cold hemagglutinins, because of the possible use of obligatory deep hypothermia or total circulatory arrest due to a diseased ascending aorta.
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2/4. Syphilitic aneurysm of the abdominal aorta: report of two cases.

    We have described two histologically confirmed syphilitic abdominal aortic aneurysms arising below the renal arteries. Serological tests were negative and the patients had in the past been treated with penicillin and bismuth. We consider that there may be a correlation between atherosclerosis and syphilis in the natural history of some abdominal aortic aneurysms and the hazard of indiscriminate use of antibiotics for the treatment of other inflammatory vessel disease may allow syphilis to develop insidiously.
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3/4. Method for resection and prosthetic replacement of aneurysm of aortic arch.

    We shall describe a case of aneurysm of the transverse aortic arch. The patient was operated upon successuflly. Severe respiratory distress owing to tracheal compression was the indication for emergency surgical therapy. A method is described comprising total cardiopulmonary bypass, hypothermia (28 C.) and local deep myocardial hypothermia. catheters to cerebral vessels are brought off the main arterial line beyond the pump. Cerebral vascular resistance regulates local blood flow. Coronary perfusion is omitted.
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4/4. Bilateral coronary ostial stenosis and aortic regurgitation due to syphilitic aortitis.

    Coronary ostial stenosis in otherwise normal coronary vessels, is a rare complication of syphilitic aortitis, and most of the cases are found at autopsy. We report here a case in which bilateral coronary ostial stenosis and aortic regurgitation due to syphilitic aortitis was diagnosed; coronary artery bypass graft and aortic valve replacement were then performed. The macroscopic finding and the histopathological examination of the ascending aorta revealed the presence of syphilitic aortitis. It is important to note that syphilis is one of the causes of coronary ostial stenosis in young adults associated with aortic regurgitation.
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