1/2. Hereditary spherocytosis in a newborn with carrier state parents--a family study.A four-hour-old male newborn was diagnosed as hereditary spherocytosis by routine blood examination. There was no family history of anemia, jaundice or splenectomy. osmotic fragility and autohemolysis tests were positive both in patient and parents. However there were no abnormal findings in physical and routine blood examinations of parents and a sibling. Hereditary spherocytosis is rather a difficult diagnostic problem during the neonatal period when there is no family history. The clinical manifestation and unusual genetic carrier pattern in the parents are discussed.- - - - - - - - - - ranking = 1keywords = physical (Clic here for more details about this article) |
2/2. Hereditary spherocytosis with congestive heart failure: report of a case.We report herein a case of 62-year-old woman with hereditary spherocytosis (HS) and congestive heart failure (CHF). Although her history revealed jaundice in the early neonatal period, she had never undergone a physical examination and thus, the diagnosis of HS and CHF was not made until the age of 61 when she complained of dyspnea and palpitations on exertion. The CHF was subsequently found to be related to severe anemia in the presence of underlying heart disease. splenectomy was performed in an attempt to relieve the severe hemolytic process. Following this, all the symptoms improved without the need for any cardiovascular drugs and she has been well throughout the 34 months follow up.- - - - - - - - - - ranking = 1keywords = physical (Clic here for more details about this article) |