1/3. Multiple congenital symmetric skin dimples.skin dimples are seldom observed in sites other than the face. We report on a male premature child who was seen at the age of 2 months for the evaluation of cutaneous depressions symmetrically located on the shoulders, elbows and in the sacral region. skin dimples have sometimes been considered a benign autosomal dominant trait. However, several authors have reported these cutaneous defects in a variety of conditions like congenital syndromes, infections, inborn errors of metabolism and mechanical trauma. In our case, the aetiology is unknown, even though maternal drug or infective exposure can reasonably be excluded as well as traumatic events. At a 3-year follow-up, the patient shows a normal psychophysical development. This appears to be the first case of a child presenting congenital, symmetric dimples in three different areas.- - - - - - - - - - ranking = 1keywords = physical (Clic here for more details about this article) |
2/3. Neurological complications in one of a sibpair with aplasia cutis congenita.We describe two sibs with aplasia cutis congenita, one of whom has developed moya-moya disease resulting in severe physical handicap and mental retardation. The presence of aplasia cutis congenita should at least alert the clinicians to the possibility of a co-existing central nervous system lesion.- - - - - - - - - - ranking = 1keywords = physical (Clic here for more details about this article) |
3/3. Delineation of the costello syndrome.We present a 15-year-old girl with mental retardation, short stature, coarse face, unusually thick, loose skin of the hands and feet, deep plantar and palmar creases, and nasal papillomata. Her history and physical findings are compared to those of 2 children initially reported by Costello and to 1 child recently reported by Der Kaloustian et al.- - - - - - - - - - ranking = 1keywords = physical (Clic here for more details about this article) |