1/35. Asymptomatic unilateral microembolic retinopathy secondary to percutaneous transluminal coronary angioplasty.BACKGROUND: Percutaneous transluminal coronary angioplasty (PTCA) for the treatment of coronary artery disease has increased in frequency as technological advances have made the procedure more effective and cost-efficient. In spite of the number of procedures that have been performed, ocular complications have rarely been reported. CASE REPORT: A case of asymptomatic unilateral microembolic retinopathy one month after PTCA is presented. Embolic events to the retinal circulation and their relationship to invasive cardiac procedures is discussed. CONCLUSIONS: The embolic ocular complications of PTCA is probably underestimated due to the lack of symptoms from the partial occlusion of the larger retinal arteries and the total occlusion of the remote smaller vessels.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
2/35. A fluorescein angiographic study of branch retinal artery occlusion (BRAO) - the retrograde filling of occluded vessels.BACKGROUND: For assessing the prognosis of a branch retinal artery occlusion (BRAO), examination of the arterial blood flow by fluorescein angiography is necessary. patients AND methods: In seven patients (mean age: 68.1, youngest 61, oldest 76 years old), with BRAO of varying involvement and extent, the disturbed retinal blood flow was demonstrated by this method. All the patients were subjected to Doppler sonography of the carotid arteries and all had a general medical examination. RESULTS: The most impressive sign was the retrograde filling of the retinal arterial and/or venous branches from the adjacent retinal vessels and capillaries. In four patients the visual acuity was better after the disappearance of the retinal edema. In one patient the visual field defect slightly decreased at follow-up. This means that not every patient with retrograde filling of dye in BRAO has a bad prognosis in terms of visual function. The extent and duration of the retrograde filling with dye and the arterial or venous passage varied from patient to patient. There was also delayed filling with an increased period of retention in an artery (which is an adverse sign in BRAO), and retrograde filling of the corresponding vein. This latter came from small adjacent veins, but the retrograde filling of an artery came from capillaries or from very small adjacent arterioles. All the patients showed signs of general systemic disease, such as occlusion or the presence of plaques in the carotid artery, absolute arrhythmia, arterial hypertension, patent foramen ovale, diabetes mellitus, hyperuricemia, factor v mutation, homocysteinemia or coronary heart disease. CONCLUSION: Retrograde filling of the retinal arterial and/or venous branches means a kind of spontaneous healing compared to a condition with complete permanent obstruction of circulation. It is recommended that fluorescein angiography should be carried out for all patients with BRAO, in order to estimate the prognosis of the vascular occlusion. This is the first published record of consecutive pictures showing the retrograde filling of retinal arteries and/or veins with BRAO. In every patient with a BRAO an extensive medical and neurological examination (including echocardiography and Doppler sonography of the carotid arteries) is essential before planning the treatment.- - - - - - - - - - ranking = 5keywords = vessel (Clic here for more details about this article) |
3/35. The diagnostic challenge of occult large vessel ischemia of the retina and choroid.Vascular occlusions of the retina and choroid can cause severe visual loss. These occlusions can occur as a result of systemic disease or after surgery. In most cases, the retinal appearance provides evidence of ischemia as the cause of visual loss. On occasion, however, clinical examination shows no objective signs of vascular occlusion, and this can lead the clinician to suspect optic nerve pathology as the cause of visual loss. This paper outlines some of the diagnostic criteria, clinical findings, and ancillary studies that can be used to differentiate between occult occlusion of the retina or choroid and optic nerve disease.- - - - - - - - - - ranking = 4keywords = vessel (Clic here for more details about this article) |
4/35. Continued lodging of retinal emboli in a patient with internal carotid artery and ophthalmic artery occlusions.Internal carotid artery or ophthalmic artery occlusions are devastating ophthalmological events which lead to severe impairment of vision. A case of multiple branch retinal artery occlusions in a 63-year-old male with internal carotid artery and ophthalmic artery occlusions on brain angiography is presented. Emboli lodging in branches of the retinal arteries were bright, glistening, yellow or orange in appearance. Such a distinctive ophthalmoscopic appearance led to the diagnosis of cholesterol emboli. Fluorescein and indocyanine green angiography disclosed delayed filling of the retinal vessels and choroid, and showed multiple hypofluorescence distal to the vessels in which the emboli were lodged. At the time of initial examination, the number of emboli lodged in retinal arteries was estimated at more than 20. As time passed, a few of the previous emboli disappeared and new emboli appeared in other sites on fundus examination. We think that the lodging of new emboli in other sites is due to the continued break-up of atheromatous tissue through the collateral circulation associated with the occlusion of the internal carotid and ophthalmic arteries.- - - - - - - - - - ranking = 2keywords = vessel (Clic here for more details about this article) |
5/35. Central retinal vein occlusion combined with cilioretinal artery occlusion.A healthy 65-year-old man with sudden profound visual loss in his right eye presented with clinical signs of central retinal venous occlusion and retinal whitening, indicative of a cilioretinal arterial obstruction. He had been diagnosed with cilioretinal artery occlusion at a private ophthalmology clinic three days before being referred to our department. On fluorescein angiogram of the affected eye, the proximal portion of the retinal arteries filled with dye 27.3 seconds after injection, indicating a delay in retinal arterial filling. Moreover, the cilioretinal artery did not fill at that phase, but went on to fill 45.1 seconds after injection. Over 63.4 seconds after the filling of the retinal arteries, the laminar flow of the retinal venous vessels appeared. This was not until 90.7 seconds after injection. This patient was elderly, had no systemic diseases, and showed non-ischemic CRVO, prolonged retinal arterial filling on fluorescein angiography, and poor prognosis in visual acuity. His clinical course seemed to favor the pathogenetic hypothesis of a primary arterial affection.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
6/35. fibromuscular dysplasia: a rare cause of cilioretinal artery occlusion in childhood.OBJECTIVE: To report a case of cilioretinal artery occlusion with angiographic findings characteristic of the "string of beads" associated with renovascular hypertension secondary to fibromuscular dysplasia of the renal artery in a child. DESIGN: Case report. INTERVENTION: The patient underwent ex vivo renal artery reconstruction with saphenous vein graft and reimplantation. MAIN OUTCOME MEASURES: The main clinical outcomes were control of severe hypertension, reversible hypertensive retinopathy, and improvement of vision. RESULTS: Revascularization of the kidney improved renal function, and renovascular hypertension was clearly improved. visual acuity improved to 20/200. CONCLUSIONS: A child with hypertensive retinopathy and arterial occlusion in the retina should undergo investigation to rule out a surgically curable hypertension. magnetic resonance angiography of extrarenal vessels may reveal other sites of involvement of fibromuscular dysplasia. Evaluation and early diagnosis of renovascular hypertension will prevent severe end-organ damage.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
7/35. Ocular massage in a case of central retinal artery occlusion the successful treatment of a hitherto undescribed type of embolism.BACKGROUND: The pathogenesis of central retinal artery occlusions (CRAO) varies, depending upon the underlying disease. An embolic origin of an occlusion often occurs. PATIENT AND methods: A 50-year-old man with an occlusion of the left internal carotid artery was examined because of a left central retinal artery occlusion. fluorescein angiography revealed that in no blood vessel could any circulation of blood be demonstrated. The slight vascular filling with dye mainly came from collateral circulation at the disc. RESULTS: Ocular massage was carried out. After a delay of several minutes, the vessels of the fundus became increasingly filled with blood. The patient noticed continuing recovery in the vision of his left eye. During fluorescein angiography, carried out one day later, white embolic clots appeared in the arteries of the papilla, some of them moving with the velocity of the blood flow through the retinal vessels and reaching the periphery of the retina and immediately disappearing. Others moved more slowly. This was seen repeatedly over several minutes. CONCLUSIONS: In this patient we have recorded in a fluorescein angiogram bright boluses visible in the blood of the retinal arteries. We suggest that conglomerations of blood cells can also cause an obstruction of blood flow. The observation of this kind of bright clots (boluses) visible in the blood of the retinal arteries we did not find described in the literature. In such a situation ocular massage is extremely helpful. Therefore, ocular massage should be carried out in every patient with CRAO.- - - - - - - - - - ranking = 3keywords = vessel (Clic here for more details about this article) |
8/35. Maculo-papillary branch retinal artery occlusions following the Wada test.BACKGROUND: The Wada test induces short-term anesthesia of one hemisphere by injection of sodium amytal into an internal carotid artery. It is an important presurgical diagnostic tool in epileptic patients. PATIENT: A 22-year-old man with idiopathic epilepsy noticed a shadow in the central visual field of his right eye immediately following a Wada test of the right hemisphere. RESULTS: The patient presented with an occlusion of two small branch retinal arteries and corresponding defects in his visual field. fluorescence angiography revealed small dense hyperfluorescent spots within the occluded retinal vessels. CONCLUSION: Branch retinal artery occlusions are a possible complication of the Wada test, possibly induced by undissolved contrast medium or sodium amytal.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
9/35. Bilateral blindness and lumbosacral myelopathy associated with high-dose carmustine and cisplatin therapy.PURPOSE: To report the early ocular pathologic findings associated with high-dose carmustine and cisplatin therapy. methods: A patient with metastatic breast carcinoma developed an acute onset of branch retinal artery occlusion, bilateral blindness, and a myelopathy involving the lower extremities after high-dose chemotherapy and bone marrow transplant. RESULTS: Histopathologic examination of the eye and optic nerves at autopsy disclosed nerve fiber layer infarction secondary to right inferior temporal retinal artery thrombosis. Patchy necrosis of both optic nerves, medulla oblongata, and spinal cord was associated with focal small-vessel thrombosis. CONCLUSIONS: The syndrome of retinal vascular occlusion, optic neuropathy, and myelopathy is associated with the high-dose chemotherapeutic agents carmustine and cisplatin. The distribution of necrosis suggests an ischemic event rather than direct neurotoxic effects.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
10/35. susac syndrome: microangiopathy of the retina, cochlea and brain.BACKGROUND: susac syndrome is characterized by the triad of branch retinal arterial occlusions, encephalopathy and cochlear microangiopathy. The underlying process is believed to be a small vessel vasculitis causing microinfarcts in the retina, brain and cochlea. methods: Analysis of two male and two female cases of susac syndrome recognized in australia. RESULTS: In this series the epidemiology, mode of presentation, ophthalmologic features, neurologic and cochleo-vestibular features, radiologic characteristics, cerebrospinal fluid findings, therapeutic interventions, clinical course and outcome of susac syndrome is examined. Key ophthalmologic differential diagnoses include systemic lupus erythematosis (SLE), Behcet's syndrome and other vasculitides such as sarcoidosis, tuberculosis, syphilis and lymphoma. Neuro-otologic features are most frequently misdiagnosed as multiple sclerosis. CONCLUSION: susac syndrome, first described in 1979, is becoming an increasingly recognized condition. Early recognition of the syndrome is important because treatment with systemic immunosuppression may minimize permanent cognitive, audiologic and visual sequelae.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
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