Cases reported "Prostatic Neoplasms"

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1/11. Renal pelvic carcinoma of horseshoe kidney caused systemic metastasis by implantation in prostate.

    A case is reported of renal pelvic carcinoma of the horseshoe kidney in a 69-year-old man, which showed an interesting metastatic pattern by implantation in the prostate. A few months after transurethral resection of the prostate for benign prostate hyperplasia and extracorporal shock wave lithotripsy for renal stones, the patient complained of severe back pain due to multiple metastatic bone tumors. autopsy revealed transitional cell carcinoma in the pelvis as well as in the prostate with remarkable vessel invasion. The clinical course and autopsy findings suggested that the systemic expansion of cancer cells from the renal pelvis was caused not only by direct metastasis but also by implantation in the prostate.
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2/11. Periprostatic subendothelial intravascular granulomatosis: a mimic of high-grade intravascular prostatic adenocarcinoma.

    A rare case of intravascular granulomatous inflammation mimicking intravascular prostatic adenocarcinoma is reported. To the author's knowledge, there have been no previous reports of prostatic or periprostatic intravascular granulomatous inflammation. A 67-year-old man presented with elevated serum prostate specific antigen (PSA) and was found to have a high-grade adenocarcinoma of the prostate. A radical prostatectomy revealed intravascular subendothelial granulomatous inflammation mimicking vascular invasion of a high-grade adenocarcinoma found elsewhere in the prostate. Immunoperoxidase stains confirmed that the subendothelial infiltrate was composed of histiocytes and not tumor cells. Periprostatic subendothelial intravascular granulomatosis is a rare event, which may mimic vascular involvement of high-grade prostatic adenocarcinoma and may result from a previous needle biopsy of the prostate. Possible mechanisms for this finding are discussed. It is important to distinguish this process from high-grade prostatic adenocarcinoma involving blood vessels for obvious clinical reasons.
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3/11. A life-threatening hematochesia after transrectal ultrasound-guided prostate needle biopsy in a prostate cancer case presenting with lymphedema.

    A 62-year-old male presenting with lymphedema at the left lower extremity was diagnosed as prostatic carcinoma by an ultrasound-guided needle biopsy. Six days after the biopsy procedure, he developed severe hematochesia. colonoscopy revealed an oozing visible vessel at the anterior rectal wall, a few centimeters from the anus. Endoscopic hemostasis with %1 athexysclerol was applicated with success. Rebleeding with same severity as the first one occurred 48 hours after the first bleeding and endoscopic hemostasis was successful again. Follow-up was uneventful.
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4/11. Subdural hematoma secondary to metastatic neoplasm: report of two cases and a review of the literature.

    Subdural hematoma secondary to dural metastases is a rare event. Vascular obstruction due to invasion of dural vessels is an important etiological factor. When this is associated with a clotting defect, the subdural hematoma can cause significant clinical symptoms and death. Two cases are presented with a review of the literature.
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5/11. klinefelter syndrome in the aged.

    Three cases of klinefelter syndrome diagnosed late in life are reported with the clinical and post-mortem findings. The diagnosis was suspected owing to the absence of testes and the presence of associated varied clinical features. The urinary follicle-stimulating hormone levels were not elevated and were very low in two of the cases. bronchopneumonia, ascending pyelonephritis and cystitis were the main causes of death but there were varied pathological findings in the prostate of benign hyperplasia, carcinoma and prepubertal gland. Marked atherosclerosis of the aorta and the lower-limb vessels were present but the coronary systems were little affected. It is suggested that, because of the presence of two X chromosomes and the absence of testes, this condition may give a female pattern of longevity, many examples being overlooked in old age on account of inadequate clinical examination. Some support for this hypothesis will be found if its incidence in the aged is shown to be greater than in the young.
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6/11. Primary carcinoid tumor of testis. Immunohistochemical, ultrastructural, and dna flow cytometric study of three cases with a review of the literature.

    The cases of three patients with primary carcinoid tumor of the testis were reported. The patients were 41, 44, and 83 years of age. At initial examination, all three had testicular masses with or without associated pain, and none had the carcinoid syndrome. The tumors measured 4.3 cm, 3.0 cm, and 6.5 cm in dimension. All three tumors manifested classic histologic features of carcinoid tumors. The neoplastic cells exhibited argyrophilia, and all were immunoreactive to chromogranin, serotonin, neuron-specific enolase, and cytokeratin. Two tumors had positive test results for gastrin and one had positive test results for substance p and vasoactive intestinal polypeptide. No tumors reacted with somatostatin, insulin, pancreatic polypeptide, or placental alkaline phosphatase. Intracytoplasmic, membrane-bound, round-to-elliptical pleomorphic granules were identified by ultrastructural analysis in all cases. dna flow cytometric analysis revealed a low degree (near-diploid) dna aneuploidy in all cases, with a dna index of 1.15 in two tumors and 1.3 in the third tumor. The three patients are alive and well 11 years, 7 years, and 6 months, respectively, after diagnosis. A total of 57 cases of this entity, including the 3 reported here, have been reported. Of these, 43 were pure carcinoid, and 14 were associated with teratoma; 6 (11.6%) patients developed metastases. Tumor size and the presence of carcinoid syndrome have been found to correlate with metastatic potential. Neither tumor necrosis nor local tumor invasion (into vessels, tunica albuginea, etc.) correlated with adverse prognosis. carcinoid tumor of the testis is a rare indolent neoplasm with potential for distant metastases.
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7/11. Laparoscopic pneumodissection: initial clinical experience.

    OBJECTIVES. We evaluated the efficacy of a new laparoscopic dissecting instrument that fires intermittent bursts of high-pressure carbon dioxide to separate tissue along natural planes. methods. The pneumodissector (PD) was used in 2 patients undergoing laparoscopic procedures. serum creatinine and bicarbonate were measured before and after the procedure, and arterial blood gases were measured before, during, and after use of the PD. Subjective assessment of the ease of dissection with the PD by the first assistant was recorded. RESULTS. acidosis and hypercarbia were not observed with use of the PD. The PD facilitated dissection along the iliac vessels, around the kidney, and in the renal hilum. CONCLUSIONS. The PD is a feasible method for rapid, blunt dissection during laparoscopic procedures.
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8/11. Transitional cell carcinoma of fossa navicularis in a man with three other synchronous malignancies.

    Transitional cell carcinoma arising from the anterior portion of the male urethra is rare, with less than 10 cases reported in the literature. Our patient had a high-grade, highly invasive transitional cell carcinoma originating in the fossa navicularis and extending proximally along the corpus spongiosum, the corpora cavernosa, and blood and lymphatic vessels. In addition, the patient had a concurrent low-grade prostatic adenocarcinoma, a large basal cell carcinoma of the nose, and a squamous cell carcinoma of the penile skin. The previously reported cases are reviewed, with particular reference to the possible association of these tumors with human papillomavirus infection.
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9/11. Tortuous and aberrant external iliac artery precluding radical retropubic prostatectomy for prostate cancer.

    A sixty-eight-year-old black man with clinical Stage A1 (T1a) adenocarcinoma of the prostate was found to have a tortuous and redundant left external iliac artery directly overlying the superior aspect of the prostate gland. The location of this blood vessel precluded radical retropubic prostatectomy. To our knowledge, this is the first reported example of this clinical situation. Computer-generated three-dimensional imaging from the computed tomography scan allowed accurate assessment of the vascular anomaly.
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10/11. An association between ANCA positive renal disease and malignancy.

    The detection of anti-neutrophil cytoplasmic antibodies (ANCA) is now a routine part of the evaluation of patients clinically suspected of suffering from small vessel vasculitis. The factor(s) that trigger the development of these autoantibodies and their role in the pathogenesis of vasculitis is still unclear. We describe four patients who presented to us since June 1990. All patients had positive ANCA serology and had clinical evidence of vasculitis. In all patients soon after the establishment of ANCA positivity, a carcinoma of either the respiratory or urinary tracts was diagnosed. We suggest that in some cases of ANCA-associated vasculitis, malignant disease may be a trigger for either the generation of these autoantibodies, or the development of vasculitis.
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