1/6. Free flap closure in complex congenital and acquired defects of the palate.Extensive palatal defects cause substantial morbidity, including nasal regurgitation, poor oral hygiene, loose-fitting obturators, and difficulty with speech. Microvascular techniques allow the surgeon to repair these complex defects with a one-stage reconstruction, in contrast to possible multistage local or regional flap reconstruction. In this retrospective review, the authors present their 5-year experience with free flap coverage of extensive palatal defects. From 1993 to 1998, 6 patients underwent free flap coverage of large palatal defects. The etiology of the large palatal defects included trauma (N = 1), neoplasm (N = 4), and a recurrent congenital cleft palatal fistula (N = 1). Three patients underwent osteocutaneous radial forearm flaps and 1 patient underwent a fasciocutaneous radial forearm flap. The remaining 2 patients underwent rectus abdominis muscle flaps. The ipsilateral facial artery and vein were used as the recipient vessels in all patients. There were no intraoperative complications (surgical or anesthetic). Postoperatively, 2 patients had surgical evacuation of small flap hematomas. One patient underwent revision of the fasciocutaneous flap. All flaps survived. In our experience, the benefits of free flap reconstruction of complex palatal fistulas seem to outweigh the risks of the operation, with reliable long-term results.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
2/6. angiomyolipoma of the palate. Report of a case.angiomyolipoma (AML) is a tumour or an hamartomatous growth that usually affects the kidney. Only rarely has AML been described in the oral cavity. The authors report a case of AML located in the palate in a 43-year-old patient. AML is composed of smooth muscle cells, blood vessels and mature fat cells. In 50% of cases, AML presents with symptoms of tuberous sclerosis. Renal AML are often invasive, may involve regional nodes and may recur, while, on the contrary, AML are most often well circumscribed and easily resected. AML seems to follow an entire benign course.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
3/6. Rare benign tumours of oral cavity--capillary haemangioma of palatal mucosa: a case report.Haemangiomas are benign tumours composed of blood vessels, they are probably developmental rather than neoplastic in origin. Haemangiomas are often present at birth but may become more apparent during life. The tumours appear as a flat or raised reddish-blue lesions and are generally solitary. They are occasionally seen on the palatal mucosa. Haemangiomas are classified on the basis of their histological appearance as capillary, mixed, cavernous or a sclerosing variety that tends to undergo fibrosis. Their differential clinical diagnosis is based on appearance. The tumours may be slowly progressive, involving extensive portions of the superficial and deep blood vessels. Function may be affected where development of the lesion is extra-invasive. Colour change on pressure is a common finding with return to the original colour on withdrawal of pressure. The case presented here was referred because of swelling and recurrent periodontal bleeding. The lesion was diagnosed as a capillary haemangioma through histopathology. Although different therapeutic procedures have been reported, in this case surgical excision was carried out under general anaesthesia following hospitalization. Despite their benign origins and behaviour, haemangiomas in the region of oral cavity are always of clinical importance to the dental profession and require appropriate clinical management. Dental practitioners and oral surgeons need to be aware of these lesions because they may pose serious bleeding risks.- - - - - - - - - - ranking = 2keywords = vessel (Clic here for more details about this article) |
4/6. Kaposi's sarcoma in a renal allograft recipient under longterm immunosuppressive therapy.A 40-year-old Caucasian male with chronic glomerulonephritis received a cadaver renal transplant in July 1973, and received continuous immunosuppressive therapy with azathioprine and prednisone. His renal function deteriorated during the autumn of 1977, and he developed haemangiomatous tumours in the soft palate and on the sole of the right foot in April 1978. Both were surgically removed and histologically confirmed as Kaposi's sarcomata. The patient died a month later of renal insufficiency. At autopsy, a Koposi's sarcoma was also present in the right lateral malleolar region. There were multiple calcifications in the lungs, vessel walls, striated muscle and subcutaneous fat. To our knowledge, this is the 29th reported case of Kaposi's sarcoma occurring in renal allograft recipients under long-term immunosuppressive therapy. It is concluded that the development of this tumour is probably related to such therapy.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
5/6. Ultrastructural study of hemangiomas. 2. Benign hemangioendothelioma of the hard palate.A case of benign hemangioendothelioma which occurred in the hard palate was observed and its electron microscopic findings were described. The endothelial cells contained an abundance of cytoplasmic filaments, but they contained a small number of weibel-palade bodies. Two types of endothelial cells, light and dark, were found in our specimen. The former had a cytoplasm with an abundance of ribosomes, rough endoplasmic reticulum and scant filaments. The latter had a cytoplasm with numerous cytoplasmic filaments and a well-developed golgi apparatus. tight junctions were seen between the endothelial cells. The majority of the pericytes were accompanied with the vessels in the tumor. Three types of pericytes were recognized: endothelial cell-like, fibroblast-like, and smooth muscle cell-like pericytes.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
6/6. Intra-vascular tumour in pleomorphic adenomas--a report of four cases.AIMS: The aim of this study was to report four cases of pleomorphic adenoma which were characterized by intra-vascular tumour. methods AND RESULTS: The patients ranged in age from 13-43 years, one was male while three were female. The tumours were situated in the parotid gland, submandibular gland and palate (two cases). The intra-vascular tumour consisted of single, clustered and solid cords of cells within multiple muscular walled blood vessels and capillaries both in the capsule and in the tumour. Immunoperoxidase staining confirmed that the intra-vascular cells were phenotypically identical to those of the tumour. The possibility that the intra-vascular tumour represents artefactual 'spillage' has been considered, however there is some histological evidence suggesting that this phenomenon represents true vascular invasion. CONCLUSIONS: The biological significance of intra-vascular tumour in pleomorphic adenomas is unknown. Thus far there has been no correlation with either recurrence or metastases.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |