1/17. Ovarian granulosa cell 'tumorlet' and mature follicles with ectopic decidua in pregnancy--a case report.Non-neoplastic, tumor like lesions are encountered in the ovaries during pregnancy. Of these pregnancy luteoma is the most common lesion mimicking an ovarian neoplasm. Ovarian granulosa cell proliferations are also reported in the ovaries removed during pregnancy as an incidental finding. The granulosa cell proliferation occurs due to the follicular stimulating hormone (FSH) like activity of human chorionic gonadotropin (hCG). We report a case of second gravida who developed uterine atonia, necessitating emergency hysterectomy. Right ovary showed extensive ectopic decidua, numerous well-formed follicles and granulosa cell tumor-like proliferation. Usually follicles are not formed in the ovaries during pregnancy. The same FSH like activity of hCG might have been responsible for the formation and maturation of follicles in this case.- - - - - - - - - - ranking = 1keywords = life (Clic here for more details about this article) |
2/17. Unilateral streaked ovary syndrome. Slotnick-Goldfarbs syndrome.A case of unilateral streaked ovary (Slotnick-Goldfarb's syndrome) is reported and documented with hormonal, chromosomal, laparoscopic, and histologic studied. It is postulated that viral oophoritis associated with mumps might explain the coexistence of a streaked ovary of a congenital origin with a hypoplastic ovary, tbat would be the expression of a factor acting in postnatal life.- - - - - - - - - - ranking = 0.33333333333333keywords = life (Clic here for more details about this article) |
3/17. Sclerosing stromal tumor of the ovary with torsion. MRI features.Sclerosing stromal tumors are rare benign ovarian neoplasms that are usually diagnosed in the second or third decade of life. Most patients with these tumors present with menstrual irregularities and pelvic pain. We present the magnetic resonance imaging (MRI) findings of a left ovarian sclerosing stromal tumor with torsion that was located in the right parauterine area, and discuss the differential diagnosis for this entity based on MRI findings. In this case, MRI demonstrated a well-defined, predominantly solid mass with a pseudolobular pattern, and showed a shift of the uterus to the left. The surgical and histopathologic aspects of the case are also described.- - - - - - - - - - ranking = 0.33333333333333keywords = life (Clic here for more details about this article) |
4/17. Ovarian insufficiency in congenital lipoid adrenal hyperplasia begins in infancy.The aim of the present study was to investigate ovarian function in a 46,XX female patient with congenital lipoid adrenal hyperplasia (lipoid CAH) during infancy and childhood. We measured serum gonadotropin and estradiol levels regularly from 6 months to 10.9 years of age. serum FSH levels were clearly elevated during the first 2 years of life; they decreased gradually until the age of 5 years and they then fell into the normal range for a prepubertal female. serum LH levels were elevated until the age of 2 years and they then fell into the normal range. serum estradiol levels were always in the normal prepubertal range. Pelvic ultrasonography performed at the age of 9 months and at 9.8 years of age showed normal uterine and ovarian morphology for a prepubertal female. In conclusion, our data suggest that ovarian insufficiency in lipoid CAH begins in infancy.- - - - - - - - - - ranking = 0.33333333333333keywords = life (Clic here for more details about this article) |
5/17. Management of ovarian hyperstimulation syndrome with chlorpheniramine maleate, mannitol, and invasive hemodynamic monitoring.ovarian hyperstimulation syndrome due to exogenous gonadotropin administration is life-threatening in its most severe form. Profound fluid shifts may occur, with concomitant cardiovascular changes. We present a case of severe ovarian hyperstimulation syndrome managed with chlorpheniramine maleate (previously shown to be effective in animal models) and invasive hemodynamic monitoring. mannitol and albumin infusions were also used to maintain urine output and intravascular volume.- - - - - - - - - - ranking = 0.33333333333333keywords = life (Clic here for more details about this article) |
6/17. Gonadal failure following busulfan therapy in an adolescent girl.A girl with philadelphia chromosome-positive CML (Ph1-positive CML) was treated with busulfan from the age of 10 years 11 months to 16 years. Before treatment she had no evidence of pubertal development and no sexual development has occurred over the ensuing 5 years. Endocrine evaluation revealed that the child had ovarian failure. The pubescent female appears to be prone to develop gonadal failure with resultant lack of sexual development when treated with busulfan during this period in her life.- - - - - - - - - - ranking = 0.33333333333333keywords = life (Clic here for more details about this article) |
7/17. Fibromatosis and massive edema of the ovary, possibly related entities: a report of 14 cases of fibromatosis and 11 cases of massive edema.Twenty-five cases of ovarian enlargement secondary to massive edema, to a hitherto undescribed lesion that we have designated fibromatosis, or to both processes were reviewed to explore the possibility of a relation between them. The patients ranged in age from 13 to 39 years. The 14 patients with pure or predominant fibromatosis usually presented because of menstrual abnormalities; two had evidence of androgen excess and three had abdominal pain. At laparotomy two involved ovaries were observed to have twisted on their pedicles. There was definite bilateral ovarian involvement in two cases and probable bilateral involvement in two others. The excised specimens measured up to 12 cm in diameter and typically had firm, white sectioned surfaces. Microscopic examination showed a proliferation of spindle cells usually separated by dense collagen, which surrounded normal follicular structures. lutein cells were present in the fibromatous areas in one patient, who was masculinized, and in the adjacent ovarian stroma in another patient, who was hirsute; a proliferation of cells of sex cord type was observed in the fibromatous areas in three cases. Six of the specimens contained focal areas of edema similar in appearance to that seen in cases of massive edema. The features of the 11 cases of massive edema were, in general, similar to those of the 40 examples of this entity reported in the literature. Six of the 11 patients had menstrual abnormalities and/or evidence of androgen excess, but most of them presented because of abdominal pain. At operation an involved ovary was observed to have undergone torsion in five of the cases; bilateral ovarian enlargement due to massive edema was present in two cases. The excised specimens, which measured up to 15 cm in diameter, typically had a watery appearance on sectioning. Microscopic examination showed edematous stroma surrounding residual normal ovarian structures. lutein cells were identified in the edematous stroma in four cases and in the adjacent ovarian stroma in three of these cases. One of these patients was masculinized and another was hirsute. Small foci of fibromatosis similar to that seen in cases of pure fibromatosis were present in eight cases. The similar age range and clinical manifestations of these two processes and the overlap in their histologic features suggest that they are closely related and may reflect differing morphologic expressions of the same underlying disorder. Some of the cases of massive edema, however, may result from the development of stromal edema in ovaries involved by hyperthecosis.- - - - - - - - - - ranking = 0.66666666666667keywords = life (Clic here for more details about this article) |
8/17. Tuboovarian autoamputation and infertility.Asymptomatic or undiagnosed tuboovarian autoamputation in teenagers may have its impact on fertility later in life. Two cases are presented with infertility following unilateral adnexal autoamputation. The importance of awareness for possible subtorsion or torsion of adnexa in childhood and adolescence and its impact on fertility are discussed.- - - - - - - - - - ranking = 0.33333333333333keywords = life (Clic here for more details about this article) |
9/17. Familial 46,XX gonadal dysgenesis.Two sisters, ages 16 and 17, presented with secondary amenorrhea. In addition, primary ovarian failure, gonadal dysgenesis, and normal karyotypes were demonstrated. The most significant finding was a history of mumps, which they caught at the same time, 10 years before the onset of the amenorrhea. This disorder suggests that etiologic and environmental factors could prevail either in utero or during childhood. These patients are presented to emphasize the importance of considering gonadal dysgenesis as a differential diagnosis in patients with secondary amenorrhea, especially when the menstrual life has been a short one.- - - - - - - - - - ranking = 0.33333333333333keywords = life (Clic here for more details about this article) |
10/17. endometriosis and tamoxifen therapy.tamoxifen is an estrogen antagonist/agonist often associated with antiestrogenic effects such as hot flushes and vaginal dryness in premenopausal women. Estrogenic side-effects, such as thromboembolic phenomena and endometrial proliferation has been reported in postmenopausal women. Paradoxically, tamoxifen has also been shown to be capable of increasing estrogen levels in premenopausal women. Since tamoxifen is being used more frequently in this group of women, potential adverse effects are only now being recognized. Two cases of premenopausal women who developed symptomatic endometriomas while on tamoxifen for breast cancer, are reported. Stimulation of endometriosis should be considered when pain and an ovarian mass develops in a woman on tamoxifen. The unique effects of tamoxifen in premenopausal women may contribute to this even in the presence of regular ovulation.- - - - - - - - - - ranking = 0.33333333333333keywords = life (Clic here for more details about this article) |
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