Cases reported "Osteolysis"

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1/6. cementoplasty and the oncologic population.

    The first and only description of percutaneous cementoplasty, to date, has been described in the French medical literature in 1994. In this series of 12 cases, radiologists successfully instilled a cement derivative into the acetabulum under fluoroscopic control. As in these cases, the major indication for cementoplasty is to provide pain control and stabilization of an osteolytic lesion. Potential complications include physical or thermal damage to the adjacent neurovascular structures, either during needle positioning or from cement leakage, respectively. Although no absolute contraindications exist, one should proceed cautiously in patients with coagulopathies. Results may be suboptimal as well in patients with pathologic fractures.
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2/6. The hajdu-cheney syndrome. Report of two cases and review of the literature.

    The hajdu-cheney syndrome includes short stature, characteristic facies, and a slowly progressive skeletal dysplasia which affects skull, spine, and long bones. Two patients with this syndrome are presented. In the first patient the most distinctive skeletal feature, acro-osteolysis, was shown to be absent at age 6 years but was present at age 11 years. diagnosis was made in the second case in the absence of acroosteolysis because of otherwise typical findings. Abnormalities affecting vision, hearing, and dentition occur and these, along with the other characteristic physical and radiographic features of the syndrome, should enable diagnosis prior to the onset of acro-osteolysis.
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3/6. Intractable vasculitis, resorptive osteolysis, and immunity to type I collagen in type VIII ehlers-danlos syndrome.

    A unique patient with type VIII ehlers-danlos syndrome and cutaneous vasculitis, resorptive osteolysis, and cardiac valvular disease is described. collagen analyses identified morphologic and physical abnormalities of type I collagen. The patient's T lymphocytes could be propagated in vitro with type I collagen and produced a 60-kd lymphokine that bound this protein. Cellular autoimmunity to type I collagen may be responsible for this patient's intractable clinical condition.
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4/6. Osteolysis of the pubic bone simulating malignancy. A case report and review of literature.

    A 78-year-old white female presented with groin pain of 3 months' duration. Radiographs revealed an osteolytic lesion in the pubic bone, simulating a malignancy or infection. A closed needle biopsy was performed and pathological findings were consistent with post-traumatic osteolysis, showing avascular necrotic tissues. A review of the literature found 16 previous cases presenting with groin pain and a radiographic lesion in the pubic bone that appeared malignant. All of the patients reported in the literature were postmenopausal women most with a recent history of trauma or increased physical activity. All of the lesions were benign and, when treated conservatively, usually resolved within 6 months.
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5/6. A 69-year-old woman with thigh pain 21 years after total hip arthroplasty.

    The following case is presented to illustrate the roentgenographic and clinical findings of a condition of interest to the orthopedic surgeon. Initial history, physical findings, and roentgenographic examinations are found on the first page. The final clinical and roentgenographic differential diagnoses are presented on the following pages.
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6/6. Solitary adenocarcinoma metastasis mimicking sarcomatous degeneration in Paget's disease.

    A rare case of mucinous adenocarcinoma presented as a solitary, metastatic deposit to a region of Paget's disease within the peripheral skeleton. Historical, physical, radiographic, and scintigraphic findings were indistinguishable from those of sarcomatous degeneration arising from pagetoid bone. This case supports the idea that when a painful, osteolytic lesion is discovered within a region of Paget's disease, bone scintigraphy has greater value of disclosing potential multifocal or multicentric disease than for providing etiologic specificity for the principal lesion.
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