1/9. Inflammatory metastatic melanoma.An 87-year-old woman developed erythema, induration and tenderness of the skin overlying each breast. One year before, she had undergone an axillary lymph node dissection because of metastases from melanoma. The primary site was unknown. A skin biopsy showed pigmented tumor nests within the dermal lymphatic vessels, and immunohistochemistry confirmed the melanocytic origin. The diagnosis of inflammatory metastatic melanoma was made.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
2/9. Ileal malignant melanoma presenting as a mass with aneurysmal dilatation: a case report.Malignant melanoma is the most common metastatic tumor of the gastrointestinal tract and can present with fairly common constitutional symptoms. A 36-yr-old woman was found to have a secondary malignant melanoma in the terminal ileum with profuse aneurysmal dilatation, which is not the typical presentation of the malignant melanoma in the small intestine. Radiologic studies revealed a large tumor involving the distal ileum with aneurysmal dilatations having afferent and efferent loops, which needed to be differentiated from malignant lymphoma and other gastrointestinal tumors. Exploratory laparotomy was done, and we found a huge mass with plentiful aneurysmal dilatations; much the same of the findings from the previous studies. Segmental resection with the surrounding omentum was done followed by end-to-end anastomosis between both ends of the remaining ileum. She had been free from any evidence of the local or systemic recurrence for one year after the completion of eighteen months of the subcutaneous interferon treatment; postoperatively however, the occurrence of metastatic mass at the right axilla rendered us from complete resection due to severe penetration into the vital nerves and vessels in the axilla.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
3/9. Carcinoma erysipelatoides from squamous cell carcinoma of unknown origin.Carcinoma erysipelatoides, also known as inflammatory metastatic carcinoma, is a rare form of cutaneous metastasis from a malignancy. The characteristic histopathological finding is metastatic tumour cells inside the dermal lymphatic ducts. It is frequently observed in patients with breast carcinoma as well as adenocarcinoma of pancreas, rectum, lung, ovary and parotid gland. We present a 66-year-old man diagnosed to have metastatic squamous cell carcinoma by aspiration cytology from an enlarged neck lymph node and a core biopsy of a left axillary mass. He subsequently received radiotherapy; however, due to intolerance to erythema and swelling on local irradiated skin, radiotherapy was deferred. skin lesions on upper chest and neck area, consisting of erythematous induration with telangiectasia and tenderness, progressed slowly and were treated as cellulitis. The erythema remained stationary with antibiotic treatment. skin biopsy shows poorly differentiated squamous carcinoma cells within dermis and dilated dermal vessels.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
4/9. vitrectomy retinotomy aspiration biopsy of choroidal tumors.We used an investigational technique for the biopsy of intraocular tumors to aid in the diagnosis of three choroidal tumors. A three-port trans-pars plana vitrectomy was performed in conjunction with retinotomy, tumor biopsy, endophotocoagulation, and air-fluid exchange. vitrectomy was used to decrease the amount of traction secondary to retained vitreous after intraocular surgery. Retinotomy sites were chosen under microscopic control to avoid large caliber retinal vessels. Then a modified tumor-aspiration technique, together with endophotocoagulation and aspiration of intraoperative vitreous hemorrhages, provided an opportunity to sample tumor tissue continually at varied depths. We have added standard vitreous surgery concepts, techniques, and instrumentation to produce vitrectomy retinotomy aspiration biopsy of choroidal tumors.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
5/9. Malignant tumor embolism: a rare presentation of malignant disease.Tumor emboli to peripheral vessels usually arise from atrial myxomas. A new case of non-myxomatous embolization is presented, as well as a review of the literature regarding embolization from previously unrecognized malignancies. Sites of origin of peripheral tumor emboli are discussed, as are possible pathological mechanisms.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
6/9. Intrapulmonary shunting causing hypoxaemia in a case of carcinoid syndrome.A case of metastatic carcinoid syndrome with hypoxaemia is described. The hypoxaemia appeared to be due to intrapulmonary shunting. There was improvement in resting and exercise arterial oxygen saturations following chemotherapy with streptozotocin and 5-fluorouracil. This was followed by a decrease in the tumour bulk which may have led to a reduction in the secretion of the vasodilator products responsible for shunting. Some features of this case suggest that the hypoxaemia might have been due to dilatation of precapillary and capillary vessels of the pulmonary micro-circulation. These features are part of the so-called 'hepatopulmonary syndrome', of which this case appears to represent a less severe form.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
7/9. myxoma in the carotid artery. Myxomatous occlusion of internal carotid artery.BACKGROUND: We describe a patient with an unusual cause of internal carotid artery occlusion resulting in a stroke. CASE DESCRIPTION: A 41-year-old woman presented with a typical acute right middle cerebral artery territory infarct. Her hematological and cardiological status was assessed, including all extracranial vessels. Carotid angiography and a biopsy were performed of the occluded right internal carotid artery and demonstrated a myxoma. Cardiac investigations to determine the source of the myxoma, including transthoracic and transesophageal echocardiograms, CT and yo-yo CT scans, and MRI of the heart, were normal. No residual tumor or potential source of the tumor was found. CONCLUSION: The cause of stroke was a myxomatous occlusion of the right internal carotid artery. An entire cardiac tumor may have embolized with no detectable residual tumor in the heart; alternatively, a myxoma may have originated as a primary tumor in the carotid artery. To our knowledge, no primary myxoma has been reported to have originated in a blood vessel.- - - - - - - - - - ranking = 2keywords = vessel (Clic here for more details about this article) |
8/9. Occult gastric cancer presenting as cor pulmonale resulting from tumor cell microembolism.Cor pulmonale resulting from tumor emboli is a rare presentation of gastric cancer, and only six similar cases have been reported in the English literature. We report the case of a 37-yr-old woman presenting with dyspnea who died of cor pulmonale. autopsy revealed signet cell carcinoma of te stomach with intra-abdominal metastasis and right ventricular hypertrophy. There were no macroscopic pulmonary emboli or parenchymal lesions, but more than 60% of the small pulmonary arteries and arterioles were occluded. In most vessels, fibrocellular intimal proliferation was the major finding with only a few entrapped tumor cells.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
9/9. Cutaneous metastasis from a presumed signet-ring cell carcinoma in a 10-year-old child.Cutaneous metastases of internal malignancies are very rare in children. In this group, neuroblastoma, leukaemia and lymphoma are the most common malignancies that may develop metastases or neoplastic infiltrates to the skin. Carcinomas have infrequently been reported in children, and cutaneous metastases from carcinoma in this group have not been described. A 10-year-old girl presented with an erythematous plaque on the left hemithorax. Histopathological findings revealed grouped signet-ring cells within the lumina of lymphatic vessels in the dermis. Immunohistochemical examination confirmed the epithelial origin of the tumour. Despite an exhaustive search, the primary site could not be determined. This exceptional observation is, to the best of our knowledge, the first report of cutaneous metastasis from occult carcinoma in a child.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |