1/5. Non-aneurysmal primary subarachnoid hemorrhage in pregnancy-induced hypertension and eclampsia.Clinical as well as neuroimaging studies of women with eclampsia or pregnancy-induced hypertension (PIH) have described a variety of neurologic manifestations, including intraparenchymal brain hemorrhage. autopsy studies have described pia-arachnoid hemorrhage in women who died of eclampsia, but radiographic studies have found only intraparenchymal hemorrhage. The author describes clinical and radiographic features in three women with subarachnoid hemorrhage associated with PIH.- - - - - - - - - - ranking = 1keywords = subarachnoid (Clic here for more details about this article) |
2/5. Severe vascular adverse effects with thrombocytopenia and renal failure following emetogenic chemotherapy and ondansetron.During late 1991, a series of severe adverse events involving thrombocytopenia, renal insufficiency and thrombotic episodes was observed in patients receiving emetogenic chemotherapy. Two patients died, one of renal failure and one of cerebral haemorrhage in the presence of thrombocytopenia. Other severe side effects included thrombosis of the aorta causing paraplegia and multifocal cerebral infarctions. Common exposure features included the use of ondansetron and dexamethasone as antiemetics, and in most of the cases high dose (100 mg/M2 or more) cisplatin. Retrospective review of a series of patients treated with similar cytotoxic regimens for similar diseases before the use of ondansetron revealed no similar adverse effects, but no substantial differences were observed in renal function or haematologic toxicity in the two groups overall. Sporadic adverse vascular events have been observed before the use of ondansetron. The mechanism remains unknown, and it is not clear whether ondansetron was a factor in the unusual incidence of such events in the present series.- - - - - - - - - - ranking = 0.060229111359379keywords = haemorrhage (Clic here for more details about this article) |
3/5. An unusual presentation of Nelson's syndrome with apoplexy and subarachnoid hemorrhage.A thirty-eight year-old lady with a history of bilateral adrenalectomy for Cushing's disease seven years previously, presented with sudden onset of severe headache, nausea, vomiting and loss of consciousness. She was somnolent and confused. She had neck stiffness, sixth nerve palsy and mydriasis on the left side. Computerized tomography (CT) and magnetic resonance imaging (MRI) studies revealed a non-homogeneous, grade IV D pituitary mass lesion associated with hemorrhage in the chiasmatic, interhemispheric, cerebellopontine, perimesencephalic cisterns and a hematoma within the frontal lobe. angiography showed only bilateral elevation of horizontal segments of the anterior cerebral arteries. According to this angiographic evidence, it was presumed that the subarachnoid hemorrhage and the intracerebral hematoma were linked to pituitary adenoma apoplexy. ACTH level was 450 pg/ml. The hemorrhagic lesion with suprasellar extension was totally removed by left pterional craniotomy. Histological examination revealed a necrotic, acth-secreting pituitary adenoma. Even though apoplexy is a well known complication of pituitary adenomas, to our knowledge subarachnoid hemorrhage and intracerebral hematoma as a result of pituitary apoplexy in the context of Nelson's syndrome has not previously been reported.- - - - - - - - - - ranking = 1.2keywords = subarachnoid (Clic here for more details about this article) |
4/5. cauda equina melanoma presenting with subarachnoid hemorrhage. A case report.The case of a 57-year-old woman with a primary melanoma of the cauda equina is reported. The peculiarity of the case is the very rare clinical presentation mimicking a subarachnoid hemorrhage. The patient underwent surgical excision of the mass. The clinicopathological and neuroradiological features are summarized.- - - - - - - - - - ranking = 1keywords = subarachnoid (Clic here for more details about this article) |
5/5. Completely thrombosed giant fusiform aneurysm in a young patient--case report.A completely thrombosed giant fusiform aneurysm of the peripheral anterior cerebral artery occurred in a 16-year-old female, with a familial and personal history of vascular headache for 4 or 5 years. She was admitted in a drowsy state with severe headache. Computed tomography revealed subarachnoid hemorrhage and intracerebral hemorrhage as a mottled and ring-like high-density area in the left paramedian frontal lobe not enhanced postcontrast. Left carotid angiography demonstrated an avascular mass and a 5 cm defect in the A3 portion of the anterior cerebral artery. The rupture of the giant fusiform aneurysm was confirmed intraoperatively.- - - - - - - - - - ranking = 0.2keywords = subarachnoid (Clic here for more details about this article) |