1/17. Acute encephalopathy and intractable seizures in a 10-year-old boy.We report a 10-year-old child with Robinow's syndrome who had a 2-week history of headaches and dizziness. On the day of admission, he developed a focal onset seizure with rapid secondary generalization. The seizures were intractable despite adequate doses of benzodiazepine, phenytoin, and phenobarbital, requiring a pentobarbital drip. Continuous electroencephalogram (EEG) monitoring showed persistence of the epileptiform discharges for 13 days. cerebrospinal fluid and brain biopsy studies were unrevealing. Mycoplasma pneumonia titers showed elevation of both immunoglobulins G and M that doubled during the tenth hospital day. High-dose methylprednisolone was begun, and within 12 hours of initiation the patient sat up and began to follow commands appropriately. The overall EEG background markedly improved. central nervous system mycoplasma pneumoniae infection should be suspected in patients with an encephalopathy of unclear etiology.- - - - - - - - - - ranking = 1keywords = nervous system, brain (Clic here for more details about this article) |
2/17. mycoplasma hominis and ureaplasma species brain abscess in a neonate.We report an infant with a mixed Mycoplasma and ureaplasma brain abscess who was successfully treated with intravenous doxycycline and erythromycin. Therapeutic concentrations of doxycycline were demonstrated in cerebrospinal fluid. This report is evidence of the potential for Mycoplasma and ureaplasma to produce focal central nervous system infection, as well as meningitis, in neonates and that use of doxycycline can be efficacious in the therapy of such infections.- - - - - - - - - - ranking = 4.7016311889321keywords = central nervous system, nervous system, brain (Clic here for more details about this article) |
3/17. Two fatal cases of meningoencephalitis associated with mycoplasma pneumoniae infection.Two fatal cases of meningoencephalitis with serological indication of Mycoplasma pneumoniae infection are reported. The patients were young boys, 13 and 17 years old. attention is drawn to the risk of sequelae or of a fatal outcome in patients where this infection is associated with symptoms from the central nervous system.- - - - - - - - - - ranking = 3.1724599255599keywords = central nervous system, nervous system (Clic here for more details about this article) |
4/17. A case of mycoplasma hominis meningo-encephalitis in a full-term infant: rapid recovery after start of treatment with ciprofloxacin.The role of Mycoplasma hominisas a causative agent for neonatal sepsis and meningitis is still unclear. meningitis secondary to M. hominisis well-described in the literature; however, M. hominiscan also be isolated from cerebrospinal fluid (CSF) obtained from infants without signs of meningitis. We present a case of a full-term infant with meningo-encephalitis with seizures, epileptic activity on the EEG, inflammation of brain tissue on a CT scan, and cloudy CSF containing elevated cell counts, decreased glucose levels and elevated protein levels. M. hominiswas identified from the CSF by culture and by polymerase chain reaction (PCR) as the only possible causative agent. Furthermore, while empiric antibiotic and antiviral treatment for neonatal sepsis had failed, the meningo-encephalitis promptly responded upon antibiotic treatment with ciprofloxacin (20 mg/kg per day i.v.), to which M. hominisis susceptible. CONCLUSION: A meningo-encephalitis developed due to infection with M. hominisin a full-term infant, from which he recovered rapidly after start of treatment with ciprofloxacin.- - - - - - - - - - ranking = 0.30583425267444keywords = brain (Clic here for more details about this article) |
5/17. Seeding of a cavernous angioma with mycoplasma hominis: case report.OBJECTIVE AND IMPORTANCE: To describe a unique case of hematogenous seeding of a cavernous angioma with the commensal organism mycoplasma hominis. CLINICAL PRESENTATION: A 40-year-old female patient presented with a severe headache and acute left facial nerve palsy. Imaging studies revealed a right frontal mass lesion with characteristics of a cavernous angioma. INTERVENTION: The patient underwent a craniotomy for cavernous angioma resection. Purulent material was noted at the time of resection, and no hemorrhage was observed. Despite antibiotic therapy, the patient required repeat craniotomies for subsequent abscess treatment. M. hominis was identified as the pathogen. CONCLUSION: M. hominis is a rare cause of brain abscesses and can be difficult to eradicate. Cavernous angiomas can be seeded hematogenously.- - - - - - - - - - ranking = 0.30583425267444keywords = brain (Clic here for more details about this article) |
6/17. Bickerstaff brainstem encephalitis associated with mycoplasma pneumoniae infection.Bickerstaff brainstem encephalitis is a clinical syndrome of ophthalmoplegia, cerebellar ataxia, and central nervous system signs and is associated with the presence of anti-GQ1b antibodies. There is a clinical continuum between Bickerstaff brainstem encephalitis and miller fisher syndrome. We describe the case of an 11-year-old boy with encephalopathy, external ophthalmoplegia, brainstem signs, and ataxia with raised titers of anti-GQ1b antibodies. He presented following a respiratory illness and had laboratory evidence of recent infection with mycoplasma pneumoniae. M pneumoniae infection has been associated with both Bickerstaff brainstem encephalitis and miller fisher syndrome. This is only the second case in the literature of Bickerstaff brainstem encephalitis with raised titers of anti-GQ1b antibodies described in association with M pneumoniae infection. The patient responded to intravenous immunoglobulin administration.- - - - - - - - - - ranking = 5.9249681996298keywords = central nervous system, nervous system, brain (Clic here for more details about this article) |
7/17. The incidence and distribution of mycoplasma fermentans (incognitus strain) in the chicago AIDS autopsy series: an immunohistochemical study. chicago Associated Pathologists.Mycoplasma incognitus is a recently described organism that was originally isolated by Shyh-Ching Lo from spleen and Kaposi's sarcoma (KS) tissue of patients with AIDS. The mycoplasm has since been found in selected AIDS autopsy cases in which there were tissues with unexplained areas of necrosis. Mycoplasma incognitus is now known to be closely related to mycoplasma fermentans. In order to determine the incidence and distribution of M. fermentans/M. incognitus in an unselected series, we performed a retrospective immunohistochemical study of 42 hiv-positive autopsies from the chicago AIDS autopsy series. One case (2.4%) was found to be positive. The patient was a 27-year-old white male homosexual who had no evidence of Kaposi's sarcoma nor of any other neoplastic disorder and who died of pneumocystis carinii pneumonia. Antigen was present in the macrophages of the patient's spleen, liver, and bone marrow but was not associated with areas of necrosis. All other tissues sampled from this case (brain, heart, testis, lymph nodes) were negative. In the remaining autopsies, organs of the reticuloendothelial system as well as other randomly selected tissues (e.g., lung, heart, testis, pancreas) were screened and found to be negative. tissues from several non-AIDS autopsies were also found to be nonreactive for M. fermentans/M. incognitus. We conclude that M. fermentans/M. incognitus is not a common agent found in the chicago AIDS population; that it may be identified in tissue without morphologic abnormality; and that it is not randomly present in non-AIDS autopsies.(ABSTRACT TRUNCATED AT 250 WORDS)- - - - - - - - - - ranking = 0.30583425267444keywords = brain (Clic here for more details about this article) |
8/17. Neurological aspects of mycoplasmal infection.Mycoplasmal infections may be complicated by a wide variety of systemic syndromes, including neurological disorders. Circumstantial evidence suggests that these are immunologically-induced. A detailed study of five patients with proven mycoplasma pneumoniae and central nervous system signs showed that immunological factors were involved and suggested that the neurological symptoms were due to a vasculopathy.- - - - - - - - - - ranking = 3.1724599255599keywords = central nervous system, nervous system (Clic here for more details about this article) |
9/17. Encephalitis lethargica-like illness in a girl with mycoplasma infection.We describe a patient with mycoplasma infection and clinical manifestations of encephalitis lethargica. The patient was brought to our attention after acute neurologic deterioration followed by a prolonged sleep-like state and the emergence of extrapyramidal features. MRI of the brain disclosed a striking pattern of subcortical involvement by the inflammatory process, corroborating the clinical picture.- - - - - - - - - - ranking = 0.30583425267444keywords = brain (Clic here for more details about this article) |
10/17. Recurrent pneumonia and encephalitis due to mycoplasma pneumoniae.Recurrent mycoplasma pneumoniae encephalitis in a young man is reported. The patient appeared not to be immunodeficient and despite the presence of a focal inflammatory brain lesion with a predominance of polymorphonuclear cells no direct evidence of inent in M. pneumoniae respiratory tract infection still is unknown the case strongly indicates that certain individuals are somehow predisposed to such complications. The case also illustrates that CNS complications may occur even during a mild mycoplasma respiratory tract infection and that the radiological findings can mimic cerebral haemorrhage or abscess necessitating neurosurgical exploration.- - - - - - - - - - ranking = 0.30583425267444keywords = brain (Clic here for more details about this article) |
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