1/9. Plasma cell granuloma of the oral mucosa with angiokeratomatous features: a possible analogue of cutaneous angioplasmocellular hyperplasia.We report a plasma cell granuloma arising in the movable mucosa of the oral cavity of a 50-year-old man. Histologically, the lesion was characterized by a dense nodular infiltrate of mature plasma cells. Immunostaining for kappa and lambda light chains confirmed a polyclonal plasma cell population. Elongated rete ridges of the overlying epithelium formed collarettes around dilated blood and lymph vessels in focal areas. Based on the overall histologic architecture, we hypothesize that these peculiar changes are secondary to local blood flow alteration with congestive vasodilation caused by a dense plasma cell infiltrate. We believe that the plasma cell population may represent the oral counterpart of the cutaneous angioplasmocellular hyperplasia.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
2/9. A case of symptomatic primary HIV infection.A 30-year-old homosexual Japanese man had fourteen days of fever, malaise, appetite loss, sore throat, and four days of diarrhea and slightly congested eyes before he developed a skin eruption. He presented with measles-like exanthems on his face, trunk, and extremities. Deep red enanthems were seen on his left buccal mucosa opposite the premolar teeth, and whitish enanthems were seen on the buccal and gingival mucosa. HIV rna was detected at the high concentration of 5.8 x 10(6) copies /ml in his serum. cerebrospinal fluid examination revealed aseptic meningitis with 5,488 copies /ml of HIV rna. Anti-HIV 1 antibodies against Gp160 and p24 tested by Western blot assay showed seroconversion on day 5 of his admission, seven days after he developed the skin eruptions. The fever lasted for three weeks from the initial onset, and the skin eruptions lasted for twelve days. Histopathologically, a mononuclear cell infiltration was seen mainly in the upper dermis surrounding small vessels and sweat ducts, with CD8 cytotoxic T lymphocytes predominant. Additionally, CD1a putative interdigitating dendritic cells had also infiltrated perivascularly, and were surrounded by CD8 and CD4 T cells. in situ hybridization study failed to detect HIV products in skin biopsy specimens. Our findings suggested that CD8 T cells and their interaction with CD1a dendritic cells in the skin may be important in inducing skin manifestations in acute hiv infections.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
3/9. Reticular mandibular gingival ridges.This paper reports five cases of a heretofore unreported condition of the gingiva named reticular mandibular gingival ridges. Occurring in middle-aged males, macroscopically, they are bilateral ridges on the mandibular attached gingivae resembling rugae and having a reticular pattern that may be mistaken for lichen planus. Microscopically, they are formed of fibrous tissue with vessels that have a minimal perivascular infiltrate; the epithelium has extension of rete ridges. Of unknown etiology, the condition does not appear to change, is innocuous and does not require treatment.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
4/9. Oral lesions of epidermolysis bullosa acquisita.Oral lesions with histologic evidence of subepidermal bullae are described in a patient with epidermolysis bullosa acquisita (EBA). Deposition of IgA, IgG, and C3 in the basement membrane zone and vasculitis with C3 deposits in vessel walls suggest the possible role of immune complexes in the pathogenesis of the disease.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
5/9. Deposition of immunoglobulin and complement in mucocutaneous lesions related to treatment with D-penicillamine.A 23-year-old man suffering from sero-negative rheumatoid arthritis developed severe penicillamine-induced mouth ulcerations and erythematous macules. Immunohistochemical staining in a biopsy specimen from the affected lingual mucosa showed substantial deposition of IgM and C3 in vessel walls below the necrotic epithelium. In the affected skin, irregular granular staining for IgG and IgM along the epidermal basement membrane zone was noted, and granular deposits of IgM were present in small vessels of dermal papillae. The mouth ulcerations healed promptly after withdrawal of the drug, whereas the macules persisted for some months. The immunohistochemical findings indicated that the drug eruptions were related to a vasculitis induced by deposition of immune complexes.- - - - - - - - - - ranking = 2keywords = vessel (Clic here for more details about this article) |
6/9. Burned-out endemic syphilis (Bejel): facial deformities and defects in saudi arabia.Endemic syphilis (bejel) is an endemic, contagious, non-sexually transmitted treponematosis of primitive communities which, if not treated, can cause deformities and defects of the face in its late stage. Several burned-out cases from saudi arabia are shown, and the techniques of plastic surgical repair are presented by word and illustrations. We describe in detail a total rhinoplasty (with panfacial reconstruction) in which a scalping flap was used as outer cover and superimposed on a classical island forehead flap based on a subcutaneous pedicle containing both frontal vessels for inner lining.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
7/9. Hyalinosis cutis et mucosae.Hyalinosis cutis et mucosae is an uncommon genetic disease characterized by accumulation of glycoproteinaceous material not only at mucocutaneous sites but also in salivary glands, central and peripheral nervous systems, eyes, nd other organs and tissues. The course of the disease is protracted, and it is not likely to regress, either spontaneously or with therapy. Although it does not usually result in decreased longevity, the disorder may produce considerable disfigurement and functional impairment. This article documents the case of a 5-year-old girl who presented with vocal weakness, misarticulations, and hoarseness; hypopigmented scarring of the arms and pubis; fibrotic thickenings of the oral and laryngeal mucosa; and serous otitis media. A tongue biopsy revealed diffuse hyaline deposits throughout the connective tissue and in a lamellar pattern about blood vessels. A diagnosis of hyalinosis cutis et mucosae was made.- - - - - - - - - - ranking = 32.196026424714keywords = blood vessel, vessel (Clic here for more details about this article) |
8/9. A hamartoma-like mass on the palate? A possible discussion regarding the components of a pigmented naevus and hyperplastic salivary gland.An extremely rare mass lesion arising on the hard palate is presented. The patient was a 49-year-old Japanese male. He had a painless, semi-globular, smooth-surfaced and partially pigmented mass located on the left hard palate with no evidence of growth for approximately 20 years. The resected specimen included hyperplastic salivary gland tissue, nerve fibres and vessels surrounded by adipose tissue. All constituent tissues showed excessive growth for this location. Also spiralling nests of naevus cells representing inactive intramucosal naevus were included. We consider the whole lesion to be a hamartoma.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
9/9. Lipoid proteinosis of the oral mucosa: case report and review of the literature.We describe a 37-year-old woman who presented with progressive mouth dryness. physical examination revealed long-standing plaques on the face and upper limbs, papular lesions of the oral cavity and tongue firmness. A lower lip biopsy was performed. light microscopy demonstrated accumulation of PAS-positive material around blood vessels, capillaries and salivary gland canaliculi as well as focally massive hyaline deposits in the submucosa. immunohistochemistry revealed widespread presence of type IV collagen in the hyaline material and around thickened blood vessels. laminin immunoreactivity was particularly strong at thickened basement membranes. The above findings were compatible with lipoid proteinosis, which is likely to involve primary perturbation of collagen metabolism and production of glycoproteins.- - - - - - - - - - ranking = 64.392052849428keywords = blood vessel, vessel (Clic here for more details about this article) |