Cases reported "Mediastinal Cyst"

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1/6. Acutely symptomatic benign mediastinal cysts.

    Usually, cystic mediastinal masses are considered as benign. However, the size of the cyst is of importance, chiefly in a closed space such as the superior mediastinum. Rarely a dramatic symptomatology may develop though this was the case in the two patients we describe, who were admitted in the department. In the first case (a parathyroid cyst), the symptoms were due to a thrombosis of the left innominate vein, and in the second case (a thyroid cyst), the severity was dominated by a dramatic compression of the trachea and the vessels. The contribution of computed tomography is nowadays undisputed. It enables the diagnosis of the cystic nature before surgery. The diagnosis can easily be confirmed by percutaneous drainage.
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2/6. thoracic duct cyst in the anterior mediastinum.

    Case report of a 60-year old asymptomatic male with a chylous cyst in the right anterior mediastinum. It communicated with the thoracic duct through a narrow vessel with a length of 4 cm. During the eight years of pre-operative observation the cyst varied in size. At one time it disappeared completely, though temporarily. The rarity of this type of mediastinal tumor is stressed.
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3/6. Calcified pleuropericardic cysts--2 cases report.

    Pleuropericardic cysts represent 5 to 7 per cent of tumours of the mediastinum. Their origin is a defect in development of pericardic coelomic cavities. They are located in the right and cardio-phrenic corner in 70 per cent of cases. They are generally asymptomatic. They are best treated by a thin needle puncture under scanography. Surgery is needed only when the cyst wall is thick. We have treated surgically 2 cases of large cysts, because of their sizes (10 cm and 13 cm of diametres respectively), and, mostly, because of their calcification. Symptomatology was dominated by respiratory signs, such as dyspnea. In one case, there were manifestations of inferior vena cava compression. diagnosis was done by roentgenography of the thorax. The surgical procedure, using right thoracotomy, revealed a calcified cyst in both cases, with a tough wall, which was resected. In one case, the removal of adhesion to the inferior vena cava injured this vessel which was sutured after partial clamping. hemorrhage was severe and 2.51 blood transfusion was necessary. The post operative course was uneventful. Clinical signs of compression disappeared in both cases.
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4/6. Thymopharyngeal duct cyst: MR imaging of a third branchial arch anomaly in a neonate.

    Third branchial arch anomalies are rare. The authors present a case report of a neonate with a rapidly growing neck mass due to cystic dilation of a persistent thymopharyngeal duct, which is a derivative of the third branchial arch. The presence of thyroid and thymic tissue in the cyst wall, the communication of the cyst with the piriform sinus, and the relationship of the cyst to carotid vessels and the sternomastoid muscle were consistent with the features of a thymopharyngeal duct cyst embedded in the thyroid gland.
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5/6. Malignant mesothelioma arising from a benign mediastinal mesothelial cyst.

    A 50-year-old man presented with a cervical lymph node metastasis of malignant tumor and a radiologically documented well-defined tumorous mass in the middle portion of the mediastinum. Under the presumptive diagnosis of an undifferentiated bronchogenic carcinoma, the patient underwent chemotherapy. However, the tumor did not respond to this treatment and showed further progression. The patient died four weeks after the lymph node biopsy. autopsy revealed a well-defined cystic tumor in the mediastinum with infiltration of the pericardium. The tumor was not attached to the lungs. By histology and immunohistochemistry, a metastasizing malignant biphasic mesothelioma was diagnosed. The tumor had metastasized to intrapulmonary perivascular and peribronchiolar lymph vessels and hilar lymph nodes. Distant metastases were found in the right and left adrenal gland and in the brain. The strictly mediastinal localization and the cystic growth pattern of the tumor strongly suggest that this mesothelioma developed from a primary benign mesothelial cyst of the pericardium with secondary transformation into a malignant mesothelioma.
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6/6. thoracic duct cyst in supraclavicular region.

    A 28-year-old female attended an outpatient clinic in October, 1989, because of a tumor in the left supraclavicular fossa, detected in a health examination. Following exploratory puncture of the tumor which yielded milky-white fluid, suggesting a cyst in the thoracic duct, she was admitted to our department. The cyst was unilocular measuring about 6 cm in diameter, and the fluid content was chyle-rich in lipids. lymphography demonstrated a lymphatic structure adjacent to the lesion and scattered lymph vessels on the cyst surface. On November 16 the cyst was resected. A restiform structure was observed between the cyst and the thoracic duct, but the presence or absence of communication was unclear. The histological diagnosis was thoracic duct cyst. thoracic duct cyst occurring in the cervical region is very rare. Our case may provide useful information as to its pathogenesis and the mode of retention of cyst fluid.
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