Cases reported "Malaria"

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1/81. guillain-barre syndrome following malaria.

    Two adult males were admitted with acute are flexic quadriplegia and bifacial and bulbar weakness 2 weeks after an acute episode of malaria, one due to Plasmodium falciparum infection (patient 1) and the other due to plasmodium vivax (patient 2). cerebrospinal fluid analysis and nerve conduction studies confirmed the diagnosis of guillain-barre syndrome (GBS). Patient 1 progressed to develop respiratory paralysis and required mechanical ventilation. He received intravenous immunoglobulins for the GBS and made a complete recovery in 6 weeks. A review of 11 cases of GBS (nine previously reported and the present two) revealed that eight patients had preceding falciparum malaria and three had vivax infection. All but two patients had distal symmetric sensory deficits. Paralysis was mild in seven cases (three due to P. vivax and four due to P. falciparum) and recovered completely in 2-6 weeks without any specific treatment. Four patients with falciparum malaria developed severe paralysis with respiratory failure, and three patients died. One patient who received intravenous immunoglobulins recovered completely (patient 1 in this report).
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2/81. Transfusion-transmitted malaria--missouri and pennsylvania, 1996-1998.

    Malaria is a rare but potentially serious complication of blood transfusion. During 1958-1998, 103 cases of transfusion-transmitted malaria in the united states were reported to CDC. This report summarizes the investigation of three cases that occurred during 1996-1998 in missouri and pennsylvania and illustrates the key features of transfusion-transmitted malaria and the importance of donor screening.
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3/81. Honeymoon malaria and "herbal" therapy: A case report.

    A marked rise in the number of cases of malaria in the UK contracted in east africa has been reported in 1998. This may be explained by the "Lariam"-media hype, poor understanding, poverty of health education, or increase in travel to more exotic destinations. European centers have experienced changes in the pattern of imported malaria and constant up-dates are essential. However even the best informed may still acquire malaria.
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4/81. Transmission of malaria tertiana by multi-organ donation.

    In this report, transmission of malaria via a liver, a kidney, and possibly a heart allograft from a single donor is described. The donor had immigrated from cameroon to germany 18 months before, but had no clinical signs of active malaria infection. The liver transplant recipient and one of the two kidney transplant patients developed febrile illness with the appearance of plasmodium vivax in blood smears 5 and 6 wk after transplantation, respectively. In the heart transplant recipient, a subclinical malaria infection was suspected based on a rise of malaria antibodies late after transplantation, whereas the recipient of the second kidney allograft had no clinical or laboratory evidence of malaria. Both liver and kidney recipients with active malaria responded to medical treatment. However, the liver transplant patient developed progressive cholestasis and died 5 months after transplantation from liver failure possibly due to side effects of the malaria medication. Other cases of malaria in solid organ recipients are briefly reviewed.
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5/81. doxycycline-induced esophageal ulceration in the U.S. Military service.

    U.S. military forces are frequently deployed with little warning to regions of the world where chloroquine-resistant malaria is endemic. doxycycline is often used for malaria chemoprophylaxis in these environments. The use of doxycycline can be complicated by esophageal injury. Two cases of esophageal ulceration will be discussed, followed by a review of the literature. doxycycline causes esophageal injury through a combination of drug-specific factors, the circumstances of drug administration, and individual patient conditions. patients with dysphagia attributable to esophageal ulceration are managed by intravenous fluid support and control of gastric acid reflux until their symptoms resolve over 5 to 7 days. The risk of esophageal injury can be minimized by use of fresh capsules, drug administration in the upright position well before lying down to sleep, and drinking at least 100 ml of water after swallowing the medication.
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6/81. Observations on malaria in Indonesian timor.

    Malaria parasitemias were found in 35% of 520 individuals from a village in Timor, indonesia. plasmodium falciparum accounted for 80% of infections. The existence of P. ovale in Timor is reported for the first time. The WHO Standard Field Test for drug resistance did not reveal significant resistance of P. falciparum or P. vivax to chloroquine.
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7/81. Application of the indirect fluorescent antibody method in a study of malaria endemicity in Mato Grosso, brazil.

    Four surveys of malaria endemicity were conducted in the Cuiaba Sector of Mato Grosso State, brazil, at 6-month intervals during the period April 1970 to September 1971; during April 1970 a survey was also conducted in the Campo Grande Sector. Over 4,000 dual specimens--blood films for parasite diagnosis and filter paper blood spots for determination of fluorescent antibody (IFA) response--were collected from the general population, including school populations whenever possible. Parasitologic examinations yielded positivity rates ranging from 0.8 to 2.3%. In the Cuiaba Sector, sero-positives (larger than or equal to 1:20) ranged from 9.3 to 13.6%; in the survey in the Campo Grande Sector only 4.3% of the specimens were positive. There was an expected increase in IFA response with age in both the proportion of positives and mean maximum titers. In the Cuiaba surveys 75 to 91% of the maximum positive responses were to the plasmodium falciparum antigen, while in Campo Grande only 46% of the maximum titers were for P. falciparum. The wide differences in malaria endemicity observed within the Cuiaba Secctor were attributed to differences in climate, geography, and degree of development of the several regions. A study of surveillance reports from 1966 through the survey dates revealed that the high rates of infection seen often resulted from detection activities in the larger cities and probably represented cases imported from endemic areas to the north and west. In order to interpret accurately the endemicity of malaria in an area and, thus, determine the necessity for introduction or continuation of control measures, thorough epidemiologic studies are necessary. The addition of a serologic method to normal surveillance can increase the accuracy of interpretation.
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8/81. Fatal falciparum malaria among narcotic injectors.

    Eleven narcotic injectors from a prison in Saigon were hospitalized with falciparum malaria. coma and intense parasitemia were common and eight patients died soon after admission. Two of three autopsied cases also had purulent pulmonary infections. No non-addicted prisoners were hospitalized for malaria. Nine more unsuspected falciparum infections were found among 29 other addicts in the prison. The clustering of malaria infections among narcotic injectors who had not been in malarious areas indicates that the malaria was transmitted by the common use of needles and syringes. Cerebral malaria in an addict may be misdiagnosed as drug intoxication. Malaria surveillance is recommended for the increasing addict population in the cities of Southeast asia.
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9/81. plasmodium malariae--a report of three cases.

    Kasaragod District of Kerala state has never reported cases of plasmodium malariae. During September 1999-March 2000 a total of 52 slides were reported as positive for P. vivax, P. falciparum and mixed infection. The expert team cross-checked these positive slides and three were found positive for P. malariae which were reported as P. vivax. All these had similar clinical features and were either imported cases from endemic areas or local population who visited endemic areas or by persons who came in as construction workers.
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10/81. Malaria deaths following inappropriate malaria chemoprophylaxis--united states, 2001.

    During January-March 2001, two U.S. citizens died from malaria after taking chloroquine alone or with proguanil for malaria chemoprophylaxis in countries with known chloroquine-resistant plasmodium falciparum malaria. chloroquine-containing chemoprophylaxis regimens are not recommended by CDC for persons traveling to areas with known chloroquine-resistant P. falciparum. This report summarizes the investigation of the two cases and underscores the need for clinicians and travelers to know the recommended options for malaria chemoprophylaxis when traveling to locations with chloroquine-resistant malaria.
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