1/270. Organ-preserving surgery of renal cell carcinoma: report of four cases.Authors removed the renal tumour of four patients by means of resection in an organ-preserving manner. Of the four patients, one had bilateral carcinoma. The right-sided carcinoma of this patient was removed by resection while the other kidney was removed radically, by transabdominal approach. In three of the four cases which were in the process of stages T1 and N0M0, organ-preserving surgery was performed in the presence of intact opposite kidneys. Authors point out the fact that the resection method might be indicated even in the case of early (T1) stage tumours with intact opposite side kidneys. Furthermore, they do not recommend the enucleation of renal carcinomas for the surgical treatment of kidney tumours, since experimental studies have proved that these tumours can be transferred into the parenchyma of the kidney through the pseudocapsule of the tumour.- - - - - - - - - - ranking = 1keywords = organ (Clic here for more details about this article) |
2/270. kidney oncocytoma.Authors review the case history of three patients with kidney tumours which had been surgically removed. In two of the cases radical nephrectomy while in one, organ-preserving surgery was performed. In all the cases histology revealed benign kidney tumours--oncocytomas. In light of the available literature authors indicate that preoperative diagnosis is almost impossible. Furthermore, it is their opinion that this benign kidney tumour has a less frequent occurrence than earlier thought.- - - - - - - - - - ranking = 0.5keywords = organ (Clic here for more details about this article) |
3/270. The role of lymphatic drainage of the liver in gallbladder cancer: a case report.We report a case of a patient with a unique lymph node relapse after right hepatectomy and aggressive lymph node dissection for gallbladder cancer. There was extensive involvement of the hepatic parenchyma from the primary tumor, but no extension to the lymph nodes or other adjacent organs. Seventeen months later, the patient underwent re-dissection of the retroperitoneal lymph nodes with right nephrectomy and partial resection of the vena cava because of lymph node recurrence at the hilum of the right kidney. This pattern of lymph node metastasis to the right side of the vena cava from gallbladder cancer invading the liver is probably due to the distinct lymphatic drainage of the liver.- - - - - - - - - - ranking = 0.5keywords = organ (Clic here for more details about this article) |
4/270. Metanephric adenoma.A 59-year old woman was diagnosed with a tumour in her right kidney. A nephrectomy was performed, and a 45 mm diameter tan-pink coloured tumour was found. microscopy revealed small, dark cells in organized arrays of small round acini and tubules with glomeruloid infoldings. A diagnosis of metanephric adenoma was made. The tumour cells proved diploid on flow cytometry and immunohistochemical staining was positive for CAM 5.2 and AE-3. FISH analysis of three chromosomes did not reveal any abnormal karyotype. It is important to differentiate metanephric adenoma from renal cell carcinoma and adult Wilm's tumour, since it has a benign course.- - - - - - - - - - ranking = 0.5keywords = organ (Clic here for more details about this article) |
5/270. Large de novo renal cell carcinoma in a 10-year-old transplanted kidney: successful organ-preserving therapy.BACKGROUND: A recent review of the Cincinnati Transplant Tumor Registry recorded 24 de novo renal cell carcinomas developing in renal allografts. However, late development of these tumors after transplantation is very rare. Only four reports exist regarding conservative surgery on kidney transplant tumors. methods: This is a report on a case of a large 6-cm de novo renal cell carcinoma in a 10-year-old transplanted kidney. Optimal therapy by transplant nephrectomy or tumor enucleation was discussed. RESULTS: Partial resections or enucleations of renal cell carcinoma are still less than ideal in carcinomas larger than 3 cm considering the higher risk of local recurrence. But the recipient in this case had done so well and had had such a high quality of life after transplantation that partial nephrectomy as therapy of choice was selected. Now the patient is 2 years tumor free. CONCLUSION: The case report demonstrates that in certain select cases of large tumors, organ-preserving surgery could be an alternative approach in combining complete tumor removal with preservation of graft function.- - - - - - - - - - ranking = 2.5keywords = organ (Clic here for more details about this article) |
6/270. Reversibility of paraneoplastic bilateral diaphragmatic paralysis after nephrectomy for renal cell carcinoma.Bilateral diaphragmatic paralysis is usually caused by anatomic lesions of both phrenic nerves (e.g., after cardiothoracic surgery), generalized neurologic diseases (e.g., primary motor neuron disease, amyotrophic lateral sclerosis) or is without a known cause (idiopathic). We report a case of a patient with renal cell carcinoma complicated by an isolated bilateral diaphragmatic paralysis without clinical or electromyographic signs of other muscle or nerve involvement. There has been progressive, though till now partial, recovery of his vital capacity rising from 44% to 72% of predicted values, and maximal inspiratory pressures during the two years following the curative resection of his renal cell carcinoma. We believe this is the first report of a paraneoplastic bilateral diaphragmatic paralysis with actual recovery after tumour therapy.- - - - - - - - - - ranking = 0.079611377523835keywords = nerve (Clic here for more details about this article) |
7/270. Neuro-psychological discorders and renal cell carcinoma: a case report and a psychological study of urological cancer patients.Several pathways for immunodepression induced by stress and injury have been speculated, with precise analysis regarding out correlations between sympathetic nerve system and immunodepressive cytokines. Here, we show an interesting case and a clinical study of psychological disorders of urological advanced cancer patients. In the case report, a male renal-cell cancer patient whose disease disappeared following interferon therapy is presented whose disease relapsed five years after therapy and eight months after a traffic injury. Careful observation of the history suggests that severe pain could destruct patient's own anti-cancer mechanisms. In the clinical study on psychological disorders of the 131 patients, a higher rate (28%) of disorders was recognised in renal-cell cancer patients than in other cancer patients. serum CRP values of the renal-cell cancer patients with the disorders was significantly higher than those of the same cancer patients without the disorders. A complicated inter-relationship between the central nercous system, various external forces, the cancer itself and the immune system may exist and have an influence on the efficacy of biotherapy.- - - - - - - - - - ranking = 0.039805688761918keywords = nerve (Clic here for more details about this article) |
8/270. A rare case of lung cancer associated with renal cell cancer and benign histiocytoma of bone.lung cancer often metastasizes to organs outside the thorax, and consequently radiological evaluation of distant metastasis has become standard procedure prior to surgery. Although positive radiological findings generally suggest distant metastasis, the possibility of the co-existence of a benign tumor and primary malignancies must be considered. Herein we report a case of surgical resection of histologically confirmed lung cancer associated with renal cell cancer and benign histiocytoma of the humerus.- - - - - - - - - - ranking = 0.5keywords = organ (Clic here for more details about this article) |
9/270. Donor origin of neuroendocrine carcinoma in 2 transplant patients determined by molecular cytogenetics.Organ transplant recipients have an increased tumor incidence owing to their immunocompromised state. The origin of such tumors, whether donor or recipient, will have a clinical impact on decision-making concerning immunosuppressive therapy, retransplantation, and for recipients of other organs from the same donors. We report molecular cytogenetic determination of donor origin in 2 cases of small-cell neuroendocrine carcinoma developing in sex-mismatched transplant recipients (kidney and liver). fluorescence in situ hybridization (FISH) analysis was performed on liver core needle biopsy material from the liver transplant patient and on liver fine needle aspiration cytopreparations from the kidney transplant patient. The results for the liver transplant patient were confirmed with microsatellite allelic analysis and with comparative genomic hybridization. In both cases, FISH showed the presence of only X chromosomes within the tumor cells, indicating the donor origin of the neoplasms. FISH is an excellent method to determine neoplastic origin in sex-mismatched transplant patients. HUM PATHOL 31:1425-1429.- - - - - - - - - - ranking = 0.5keywords = organ (Clic here for more details about this article) |
10/270. Fine-needle aspiration of chromophobe renal-cell carcinoma metastatic to the thyroid gland.Chromophobe renal cell carcinoma is an unusual variant of renal carcinoma that has less aggressive behavior than clear cell carcinomas. There are few documented cases of metastases, none of which occurred in the thyroid gland. A case is presented of chromophobe renal cell carcinoma metastatic to the thyroid eight years after right nephrectomy, suspected by FNA-biopsy and confirmed histologically. Although metastases of chromophobe renal cell carcinoma are rare, they may also present in thyroid, even many years after primary tumor diagnosis, just like clear cell carcinomas. Even though the FNA cytology of chromophobe renal cell carcinoma has distinctive features, in the context of the thyroid, it can be mistaken for a primary tumor of that organ. In our case, the history of a previous renal tumor was essential in suggesting a metastatic lesion, and histologic and ultrastructural features allowed its precise identification.- - - - - - - - - - ranking = 0.5keywords = organ (Clic here for more details about this article) |
| | Next -> |