1/10. A case of familial angiolipomatosis with Lisch nodules.Familial angiolipomatosis is a rare syndrome that may be confused clinically with neurofibromatosis type 1. This condition is most often inherited in an autosomal recessive manner; however, several reports have been published suggesting an autosomal dominant mode of inheritance. Angiolipomatosis, although somewhat disfiguring, is a benign condition with no known association with malignant neoplasms. This is in contradistinction to neurofibromatosis, an autosomal dominant syndrome associated with a myriad of benign and malignant neoplasms. It is, therefore, important to discriminate this entity from neurofibromatosis when a patient presents with multiple subcutaneous tumors and a family history of similar lesions. Described is a case of a prison inmate with a history of seizures and "neurofibromatosis" without clinical documentation. Lisch nodules were noted on the irides. Postmortem examination showed multiple subcutaneous yellow tumors on the chest and arms. Fine-needle aspiration of 1 mass yielded adipose tissue with prominent vessels; histologic sections of another mass showed angiolipoma. The remainder of the autopsy showed significant coronary artery disease and a remote cerebral infarction of the temporal lobe but no signs of neurofibromatosis. We feel that the presence of multiple angiolipomas in combination with Lisch nodules lends credence to the proposed relationship between fatty tumors and neurofibromatosis suggested by other authors.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
2/10. Histopathological findings of X-linked retinoschisis with neovascular glaucoma.BACKGROUND: X-linked retinoschisis (XLRS) is rarely complicated by neovascular glaucoma. Only a few reports of XLRS histopathological findings with neovascular glaucoma have been published. methods: A 41-year-old man with XLRS complicated by neovascular glaucoma in his left eye was examined with electroretinography, B-scan, ultrasound biomicroscopy and computed tomography. He was examined by ophthalmoscopy and fluorescein angiography in the other eye. An enucleation was performed in his left eye due to uncontrollable high intraocular pressure and persistent ocular pain. We examined the enucleated eye histopathologically. RESULTS: Examination of the enucleated eye showed nuclear sclerosis of the lens, pigmented retrolental membrane and retinoschisis which separated the inner layer of the retina and made a large space in the vitreous cavity without any apparent detachment of the outer layers of the retina. Sclerotic vessels were present histopathologically in both the inner and outer layers of the retina. There was a peripheral anterior synechia, ectropion uveae and a fibrovascular membrane, which contained many lumina of neovascularization, indicating marked rubeosis iridis. Small cystic spaces were observed in both the schitic retina in the peripheral region and the foveal schisis at the outer layer of the retina. The photoreceptor cells had become markedly atrophied and multiple regions of calcification were observed. The optic nerve showed severe atrophy with gliosis, but the central retinal artery and vein were still open within the nerve. CONCLUSIONS: These histopathological findings suggest that rubeosis iridis may have developed secondarily to retinal ischemia due to occlusion of the retinal blood vessels.- - - - - - - - - - ranking = 2keywords = vessel (Clic here for more details about this article) |
3/10. iris microhemangiomas.iris microhemangiomas (IM) are benign proliferations of small, twisted blood vessels along the pupillary margin. They are usually bilateral and appear to be developmental in nature. IMs most commonly occur in patients with myotonic dystrophy and adult-onset diabetes mellitus, but have also been associated with respiratory disease, congential heart disease, and central retinal vein occlusion. Additionally, they may be found in individuals without obvious ocular or systemic abnormality. The etiology remains obscure. In this report, illustrative cases are followed by a brief discussion outlining typical clinical manifestations, etiological considerations, and possible implications.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
4/10. Changes in the contralateral eye in uncomplicated persistent hyperplastic primary vitreous in adults.In two adults (a 62-year-old man and a 71-year-old woman) uncomplicated full-blown unilateral persistent hyperplastic primary vitreous was diagnosed on the basis of characteristic clinical features and ultrasonography. In the contralateral uninvolved eyes, we found open-angle glaucoma, anomalous blood vessels along the entire circumference of the anterior chamber angle, band keratopathy, and heterochromia iridis. The axial length of one involved eye was about 0.85 mm larger than that of the uninvolved eye.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
5/10. light microscopic and electron microscopic histopathology of an iris microhaemangioma.A patient who had been observed to have an iris microhaemangioma (capillary haemangioma), confirmed on fluorescein iris angiography, came to cataract surgery. The lesion was excised at the time of surgery and submitted to light and electron microscopic study. It had the features of a hamartoma of the capillary haemangioma type, with its characteristics being specific for vessels seen in iris tissue.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
6/10. argon laser treatment of an abnormal angle vessel producing recurrent hyphema.Spontaneous hyphema has been linked to many conditions. We describe a patient with recurrent spontaneous hyphema caused by an abnormal angle vessel without associated rubeosis iridis, glaucoma, or other vascular abnormalities as documented by iris fluorescein angiography. After treatment with several sessions of argon laser photocoagulation, the patient has remained asymptomatic during ten months of follow-up.- - - - - - - - - - ranking = 5keywords = vessel (Clic here for more details about this article) |
7/10. Fine structure of tapioca melanoma of the iris.A case of a tapioca melanoma of the iris is studied by light and electron microscopy. Nodular elevations of the tumour were composed of spindle B- and epitheloid cells and of what appeared to be intermediate types. Tiny structures scattered over the entire tumour consisted of smaller epitheloid cells, many of which were found around superficial tumour vessels. Evidently, tapioca melanoma of the iris does not represent any specific histopathological entity. Tapioca melanoma of the iris is a low-grade malignant, locally aggressive tumour with a chronic clinical course.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
8/10. iridocyclitis and an iris mass associated with secondary syphilis.A 34-year-old white man developed iridocyclitis and an iris mass. The iridocyclitis was preceded by a nodular rash which spared the palms and soles. An anterior segment fluorescein angiogram was performed which showed numerous permeable vessels. An ultrasound examination of the mass showed that it extended to the ciliary body. He had both a positive RPRCT and FTA-Abs. A skin biopsy was done which disclosed the nodules to be a rare form of secondary syphilis. The patient was treated with topical steroids and a cycloplegic agent, and later prednisone and intravenous penicillin, with eventual resolution of iris mass, iridocyclitis and skin nodules.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
9/10. disseminated intravascular coagulation in infancy and in the neonate. Ocular findings.We report two cases of neonatal disseminated intravascular coagulation (DIC). One case is associated with placenta previa and respiratory distress, and the other shows hemorrhage with Gram-negative sepsis. In both cases, results of autopsy show microscopic confirmation of DIC in several body tissues. One pair of eyes demonstrates intraocular hemorrhages and intravascular fibrin in the choriocapillaris (a typical manifestation) and intravascular fibrin in the ciliary body vessels of one eye. In addition, the other pair of eyes shows involvement of iris vessels, a unique finding, as is intraretinal intravascular fibrin in one eye of the same patient.- - - - - - - - - - ranking = 2keywords = vessel (Clic here for more details about this article) |
10/10. Occult iris erosion. A treatable cause of recurrent hyphema in iris-supported intraocular lenses.A 78-year-old man underwent intracapsular cataract extraction with implantation of a Binkhorst four-loop lens. Two years later he developed recurrent hyphema, glaucoma, diffusion of blood into the vitreous, and reduction of visual acuity to 3/200. iris fluorescein angiography demonstrated a localized network of prominent collateral vessels without fluorescein leakage above the pupil, deflection and compression of radial iris vessels by the superior lens posts, and a focal area of leakage adjacent to one of the posts. argon laser photocoagulation obliterated the abnormal vessels in each of these areas, eliminated the recurrent hyphema and glaucoma, and permitted recovery of 20/80 visual acuity. The patient died suddenly three months after iris photocoagulation. Histopathologic study of the eye demonstrate erosion of iris stroma and displacement of iris vessels by the lens posts, as well as the vascular effects of successful photocoagulation therapy.- - - - - - - - - - ranking = 4keywords = vessel (Clic here for more details about this article) |
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