Cases reported "Hypervitaminosis A"

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1/2. Epiphyseometaphyseal cupping of the distal femur with knee-flexion contracture.

    An 11-year-old child with a history of receiving megadoses of vitamin a as an infant, and a 4-year-old child with a history of fulminant staphylococcal septicemia with multiple joint involvement presented with recalcitrant knee-flexion contractures. Roentgenography revealed epiphyseometaphyseal cupping (ie, epiphyseal invagination) of the distal femur. osteotomy resulted in only temporary correction. Our experience suggests that in the skeletally immature child, skin traction, physical therapy, splinting, and, in some instances, two-pin tibial traction should be the treatments of choice.
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ranking = 1
keywords = physical
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2/2. vitamin a toxicity in a physical culturist patient: a case report and review of the literature.

    Excessive intake of vitamin a may produce acute or chronic toxicity. vitamin a can be consumed in foods, fortified products and supplements. We present a case of a young physical culturist man who was referred to our Unit because of chronic liver disease of unknown origin. The patient had a history of increased vitamin a intake from natural source with the addition of high dose of vitamin a supplements with the purpose of improving his muscular development. Our patient showed chronic liver disease with severe fibrosis, signs of portal hypertension and marked hyperplasia of Ito cells. In conclusion, chronic vitamin a toxicity may produce severe liver damage and should be recognized in the differential diagnosis of chronic liver diseases.
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ranking = 5
keywords = physical
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