1/77. A new "anonymous" type of haemangioendothelioma.BACKGROUND: Our report may contribute to a better understanding of the different possible presentations of endothelial tumors. methods AND RESULTS: We report a new type of haemangioendotheliomatous tumor of uncertain aggressiveness arisen in a benign haemangioma of the scalp and represented by a proliferation of small- and medium-sized arborescent vessels whose walls were totally replaced by endothelial-like, atypical cells. CONCLUSIONS: The features of our case do not fit those of the many types previously reported in the literature. As regards the name, we prefer to consider this new variety as an anonymous type in order to avoid further confusion on a topic deserving a drastic review.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
2/77. Hepatic hemangioendothelioma: prenatal sonographic findings and evolution of the lesion.We describe a case of hepatic hemangioendothelioma that was first suspected based on prenatal sonographic findings at 19 weeks' menstrual age. At 16 weeks, the patient presented with a markedly elevated maternal serum alpha-fetoprotein level. Serial sonographic examinations revealed that the fetus had cardiomegaly, hepatomegaly with a hepatic mass and dilated intrahepatic vessels, a single umbilical artery, and a placental chorioangioma. Arteriovenous shunting within the hepatic mass was seen using color Doppler and pulsed Doppler sonography. An enlarged artery arising from the abdominal aorta supplying the mass was demonstrated. Postnatal physical examination and radiologic studies supported the diagnosis of hepatic hemangioendothelioma. The evolution in the sonographic appearance of this hepatic lesion in utero over a 17-week period is described.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
3/77. Kaposiform hemangioendothelioma of the thymus.Kaposiform hemangioendothelioma is a rare pediatric neoplasm that presents most commonly in the soft tissues. We report the case of a 1-month-old infant who presented with stridor and was found to have a diffusely infiltrating tumor in the thymus that extended into the pericardium and up the carotid sheaths. Histologic examination revealed a vascular tumor infiltrating among the lobules of the lymphocyte-depleted thymus. The lesion had features of both a capillary hemangioma and Kaposi sarcoma. Immunoperoxidase studies on formalin-fixed, paraffin-embedded tissue demonstrated the neoplastic endothelial cells to be positive for vascular markers CD31 and CD34. Antibody to factor viii-related antigen labeled feeding vessels, but failed to stain the lobules of tumor. Although these tumors have been treated in a fashion similar to capillary hemangiomas in the past, it may be important to differentiate Kaposiform hemangioendotheliomas because of their association with kasabach-merritt syndrome and recent success with more aggressive chemotherapy regimens.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
4/77. Intravascular papillary endothelial hyperplasia (Masson's tumor) manifesting as a lateral neck mass.Intravascular papillary endothelial hyperplasia is a benign lesion of vascular origin that is caused by an excessive proliferation of endothelial cells in normal blood vessels or vascular malformations. We report the case of a 26-year-old man who had such a lesion deep within the soft tissues of his neck. Imaging studies revealed a 6-cm-diameter mass, with its epicenter in the right retromandibular space. The mass extended into the right parapharyngeal space and compressed the pharynx. The mass was excised, and the patient recovered uneventfully. We discuss the management of this lesion, with emphasis on radiologic and histologic assessment and the differential diagnosis.- - - - - - - - - - ranking = 17.076407885124keywords = blood vessel, vessel (Clic here for more details about this article) |
5/77. Vascular tumors simulating occlusive disease.Two cases of vascular tumors of large vessels with intraluminal growth simulating venous thrombosis and arterial occlusive disease are reported. One was a borderline malignant epithelioid hemangioendothelioma of the femoral vein and the other a malignant epithelioid angiosarcoma of the carotid artery. Immunohistochemical studies permitted to classify the tumors. Treatment consisted in surgical resection. No recurrence and no metastasis are noted at 24 months. uncertainty regarding biological behaviour of vascular tumors and treatment persists.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
6/77. hemangioendothelioma of the sphenoid bone: a case report.hemangioendothelioma is borderline or intermediate type of vascular neoplasm. hemangioendothelioma is rare lesion that constitutes less than 0.5% of the malignant tumors of bone. We present a case of low-grade hemagioendothelioma of the skull in a 29-yr-old woman. She had pain, diplopia and exophthalmos of the left eye. Radiographic images showed a relatively well-demarcated, expansile osteolytic lesion with irregularly thickened trabeculae and calcifications in the left greater wing of sphenoid bone. Histologically, the tumor was an infiltrative vasoformative lesion. The vessels are generally well-formed with open or compressed lumina surrounded by endothelial cells showing mild atypia. It lacked frequent mitotic figures and severe atypia. Although excessive bleeding occurred during the operation, the mass was totally resected. Postoperative radiation was not necessary. She is free of disease and well 6 months postoperatively.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
7/77. Kaposiform hemangioendothelioma in adult. Report of a case with amianthoid-like fibrosis and angiectases.A rare case of kaposiform hemangioendothelioma in adult is reported. The 11 x 7 x 5 cm tumor was excised from deep subcutis of the abdominal region in 37-year-old man. No signs of kasabach-merritt syndrome or lymphangiomatosis were present. Besides typical pattern of kaposiform hemangioendothelioma, following unusual features were found: dilated vessels producing a gross impression of spindle cell hemangioma, areas of amianthoid-like fibrosis, and diffuse immunoreactivity for CD99. The differential diagnosis included mainly spindle cell hemangioma (hemangioendothelioma), hemangiopericytoma-like solitary fibrous tumor, and Kaposi's sarcoma.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
8/77. Reactive angioendotheliomatosis secondary to dermal amyloid angiopathy.Reactive angioendotheliomatosis (RAE) is a rare benign cutaneous vascular proliferation characterized by intravascular hyperplasia of endothelial cells and tuft-like proliferation of vessels. A 75-year-old man had erythematous and violaceous macules, some stellate and others arranged in a livedoid pattern, evolving toward necrosis with central areas having an "atrophie blanche" appearance spread on the trunk, inguinal folds, and right thigh. He was on hemodialysis and had a benign monoclonal gammopathy. Cutaneous biopsy revealed RAE characterized by the proliferation of epithelioid and spindle-shaped cells in superficial and middermis lining vascular channels, arranged in clusters, and sometimes displaying an intravascular growth pattern. These cells stained for CD31, CD34, and actin. Interestingly, prominent amyloid deposits were found in the wall of some vessels in deep dermis, often causing obstruction of their lumina. The cause of RAE is unknown, but it can be associated with infections, antiphospholipid syndrome, dysglobulinemia, cryoproteinemia, and lower extremities arteritis, and it may occur near arteriovenous fistulas. In this patient, we believe that RAE was caused by obliteration of dermal vessels by amyloid deposits. Indeed, it is thought that RAE could be caused by ischemia secondary to vascular obstruction. This is the first reported patient with RAE associated with amyloid deposits.- - - - - - - - - - ranking = 3keywords = vessel (Clic here for more details about this article) |
9/77. Intravascular papillary endothelial hyperplasia of the lung.Intravascular papillary endothelial hyperplasia (IPEH) is a benign vascular endothelial proliferation, which is usually confined to the lumen of preexisting vessels or vascular malformation. IPEH usually presents as a single lesion, and it rarely involves the lung. We describe a rare case of intrapulmonary IPEH presented by multiple variably sized, well-defined nodules occurring in a 52-year-old woman.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
10/77. Congenital composite hemangioendothelioma: case report and reappraisal of the hemangioendothelioma spectrum.BACKGROUND: Composite hemangioendothelioma is the most recently described entity of the hemangioendothelioma (HE) spectrum. To the best of our knowledge, only eight cases of this entity have been hitherto described. All of the previous cases affected adults; local recurrences were observed in three cases, and one case showed lymph node metastasis. We herein describe a new and previously unreported congenital case of this rare vascular tumor, arising on the acral extremity of the left forearm, which was diagnosed when the patient was 23 years old. RESULTS: The histological examination disclosed a heterogeneous vascular neoplasm composed of retiform HE-like (80%), spindle cell hemangioma-like (15%), cavernous hemangioma-like (approximately 3%), epithelioid HE-like (approximately 2%) areas, and rare foci with an angiosarcoma-like pattern (< 1%). A distinctive and unique finding of the present case was the presence of large granular eosinophilic macrophages filling some vessels of the retiform HE-like areas. A below-elbow amputation was performed. The patient is alive and well, without evidence of residual or metastatic disease 7 years after the treatment. CONCLUSIONS: The authors expand the concept of composite hemangioendothelioma by adding a congenital case and provide a reappraisal of the hemangioendothelioma spectrum.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
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