11/45. Cross-reactivity with tagetes in arnica contact eczema.A 69-year-old patient, with known mercury and adhesive plaster allergy, developed facial dermatitis within 24 h of contact with arnica (arnica). skin testing showed positive reactions to arnica and, among various other plants of the Compositae, also to tagetes sp. hybr. (marigold). Cross-reactivity between tagetes and arnica has not previously been described.- - - - - - - - - - ranking = 1keywords = allergy (Clic here for more details about this article) |
12/45. Allergic contact dermatitis from chironomids.Although Type I allergy to chironomids is well-known, allergic contact dermatitis caused by these cosmopolitan insects has not previously been reported. In the case we describe in this report, patch tests disclosed a delayed-type hypersensitivity to 4 different species of chironomids (larvae of Chironomus thummi, Chironomus plumosus, and 2 different species of Glyptotendipes) as the probable cause of airborne facial contact dermatitis. An additional asymptomatic immediate-type allergy to chironomids was demonstrated by scratch tests and specific IgE. The possible sources of exposure to chironomids, their allergens and their distribution are discussed with regard to clinical implications.- - - - - - - - - - ranking = 2keywords = allergy (Clic here for more details about this article) |
13/45. Facial erythema as a result of benzophenone allergy.benzophenones are common causes of photoallergy and are increasingly used in products other than traditional sunscreens. patients may be unaware of any sunscreen exposure when using a product such as shampoo containing benzophenone. benzophenones also may produce photoallergic contact urticaria, in addition to delayed contact and photocontact dermatitis, which may complicate the clinical presentation. Allergy to benzophenone should be considered in the diagnosis of patients with patchy erythema of the face and neck that is not typically eczematous and that may otherwise be attributed to a rosacea diathesis, lupus erythematosis, or simple flushing. Patch and photopatch testing are indicated to evaluate these patients for allergy to benzophenone.- - - - - - - - - - ranking = 6keywords = allergy (Clic here for more details about this article) |
14/45. Contact orofacial granulomatosis caused by delayed hypersensitivity to gold and mercury.Orofacial granulomatosis, an entity with characteristic clinicopathologic features, is thought to be a reactive process. The authors describe orofacial granulomatosis associated with contact allergy to gold in dental crowns in one patient and a possible allergic contact reaction to mercury from dental fillings in another one. Thus allergic contact dermatitis to the metals gold and mercury should be considered as a possible etiologic agent of orofacial granulomatosis.- - - - - - - - - - ranking = 1keywords = allergy (Clic here for more details about this article) |
15/45. Systemic acyclovir reaction subsequent to acyclovir contact allergy: which systemic antiviral drug should then be used?Allergic contact dermatitis caused by acyclovir is rare. We report the 5th case of systemic acyclovir reaction subsequent to acyclovir contact dermatitis, with investigations made to determine an alternative antiviral treatment. A 23-year-old woman, after dermatitis while using Zovirax cream, went on to develop urticaria after oral acyclovir. patch tests were performed with the components of Zovirax cream (acyclovir, propylene glycol and sodium lauryl sulfate) and with other antiviral drugs. patch tests were positive to Zovirax cream, acyclovir, valacyclovir and propylene glycol. Patch and prick tests with famciclovir were negative, but its oral administration caused an itchy erythematous dermatitis on the trunk and extremities. Our patient developed a systemic acyclovir reaction subsequent to acyclovir allergic contact dermatitis, with cross-reactions to valacyclovir and famciclovir. Their common chemical structure is the 2-aminopurine nucleus. It is probably this part of the molecule that provokes both contact allergy and systemic reactions. The only antiviral drugs not having this core are foscarnet and cidofovir, and these could therefore be alternatives.- - - - - - - - - - ranking = 5keywords = allergy (Clic here for more details about this article) |
16/45. Photocontact allergy to diallyl disulfide.Although phototoxic reactions to plants are common, photoallergic contact dermatitis to plants and plant products rarely occurs. Our objective was to review the importance of including diallyl disulfide in the evaluation of patients with suspected photosensitivity. Phototests for ultraviolet B, ultraviolet A, and visible light as well as patch tests and photopatch tests for 49 allergens from the new york University skin and Cancer Unit Photopatch Test Series were performed. Three patients had positive photopatch-test results to diallyl disulfide, which is the allergen in garlic. The authors conclude that although photocontact allergy to diallyl disulfide is rare, this allergen should be included in photopatch-test series.- - - - - - - - - - ranking = 5keywords = allergy (Clic here for more details about this article) |
17/45. latex allergy in dentistry. review and report of case presenting as a serious reaction to latex dental dam.latex allergy may have severe consequences including development of anaphylaxis. This report describes a patient who underwent a reaction to latex dental dam manifesting as erythema, facial swelling and mild airway compromise. Restorative procedures under latex dental dam were performed under local anaesthesia on two occasions resulting in reactions of increasing severity. Following the first event the cause of the reaction was undetermined, but attributed to a possible allergy to local anaesthetic, and managed with corticosteroids and antihistamines. On a subsequent occasion the swelling was more severe, associated with difficulty in swallowing and mild airway compromise, and was managed as previously with adrenaline also being required. latex allergy was subsequently confirmed.- - - - - - - - - - ranking = 9.1200944066905keywords = allergy, latex (Clic here for more details about this article) |
18/45. Occupational contact dermatitis from a grease.BACKGROUND: Contact allergy to grease is rare and often not even suspected. We investigated such a case in which the detected allergen was the stabilizer in the grease, which is rarely found as an allergen. OBJECTIVE: Thin-layer chromatography (TLC) was used in a novel way and helped detect the allergen. methods: Patch testing with our standard series, a metal-working series, the different substances individually, the grease in serial dilution and extracts of personal objects, the TLC plate. gas chromatography-mass spectrometry was also used. RESULTS: Test results indicated contact allergy to grease containing N-phenyl-1-naphthylamine and contact allergy to Disperse Orange 1, N-cyclohexyl-N'-phenyl-4-phenylenediamine, N-isopropyl-N'-phenyl-4-phenylenediamine, and N,N'-diphenyl-4-phenylenediamine. CONCLUSION: N-phenyl-1-naphthylamine was the main cause of the patient's dermatitis. This case report underlines the importance of testing the patient's own products and also underlines the benefit of using TLC strips for patch testing and of visiting the workplace to get correct information about exposure conditions.- - - - - - - - - - ranking = 3keywords = allergy (Clic here for more details about this article) |
19/45. Allergic contact dermatitis from salicyl alcohol and salicylaldehyde in aspen bark (populus tremula).Salicyl alcohol or 2-methylolphenol is a well-known allergen in phenol-formaldehyde resins and a strong sensitizer in guinea pigs. There is 1 previous report of allergic contact dermatitis from salicyl alcohol in aspen bark. We describe a second case with concomitant allergy to salicylaldehyde. An elk researcher who had handled leaves from various trees presented with eczema of the hands, face, flexures, trunk and extremities. Patch testing showed sensitivity to salicyl alcohol, salicylaldehyde, balsam of peru (myroxylon pereirae resin), aspen wood dust and an extract prepared from the bark of aspen (populus tremula). Weaker reactions were observed to bark extracts of rowan (sorbus aucuparia), tea-leaved willow (salix phylicifolia) and goat willow (salix caprea). We analysed salicyl alcohol and salicylaldehyde in the bark extracts and found the 2 chemicals in equal amounts, about 0.9 microg/mg in aspen bark and in lower concentrations in rowan and the willows. We did not find either of the chemicals in the test substance of balsam of peru (myroxylon pereirae). Besides salicyl alcohol, salicylaldehyde is also recommended to be used to screen for contact allergy to aspen. Both of these chemicals should be tested in forest workers in areas where aspen is growing.- - - - - - - - - - ranking = 2keywords = allergy (Clic here for more details about this article) |
20/45. Use of hyaluronidase in the treatment of granulomatous hyaluronic acid reactions or unwanted hyaluronic acid misplacement.BACKGROUND: In the past, reactions or misplacement of soft tissue fillers has been fraught with anxiety because time has been the main thrust for improvement in spite of ancillary treatments. Hyaluronidase is an enzyme that dissolves hyaluronic acid in the skin and also assists in the management of granulomatous foreign-body reactions to hyaluronic acid. These reactions may be caused by allergy to the material or immunologic response to the protein contaminants in the hyaluronic acid preparations. Dissolution of material in erroneous placement of material and in allergic reactions can be a time saver and a deterrent to patient dissatisfaction. OBJECTIVE: To evaluate the use of hyaluronidase in the treatment of both allergic reactions and the erroneous misplacement of hyaluronic acid in the skin. methods: A case of persistent granulomatous reaction to injectable hyaluronic acid and a case of hyaluronic acid erroneous misplacement with their successful subsequent treatments using intracutaneous hyaluronidase are reported, along with illustrative examples of hyaluronidase use. RESULTS: The use of hyaluronidase reduced the patient discomfort within 24 to 48 hours, deterring any patient anxiety or patient dissatisfaction. CONCLUSIONS: Hyaluronidase has a place in the treatment of allergic reactions to hyaluronic acid [corrected] and in the erroneous misplacement of the material.- - - - - - - - - - ranking = 1keywords = allergy (Clic here for more details about this article) |
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