1/5. Menkes' kinky hair disease: a light and electron microscopic study of the eye.light and electron microscopic studies of the ocular tissue of a case of Menkes' kinky hair disease are described. The copper deficiency responsible for this systemic and neurologic disease appears to cause a progressive degeneration of retinal ganglion cells, loss of nerve fibers, and optic atrophy. The pigment epithelium is also abnormal with only small and irregular melanin granules present among electron-dense inclusion bodies. Abnormal elastica is present in Bruch's membrane.- - - - - - - - - - ranking = 1keywords = nerve (Clic here for more details about this article) |
2/5. optic nerve manifestations of human congenital cytomegalovirus infection.A Latin American male and a white female infant who had a cytomegalovirus infection on the first day of life had unilateral optic nerve hypoplasia. A white male infant who had cytomegalovirus isolated at 5 weeks of age had a unilateral partial coloboma of the optic nerve. A 4-month-old black infant with cytomegalovirus infection diagnosed at 2 days of age had a unilateral complete coloboma of the optic nerve associated with microphthalmia. optic nerve involvement was an important manifestation of this disease.- - - - - - - - - - ranking = 8keywords = nerve (Clic here for more details about this article) |
3/5. Central serous choroidopathy misdiagnosed as a manifestation of multiple sclerosis.Visual loss secondary to macular disease can be differentiated from optic nerve lesions relatively easily in the office by simple and reliable noninvasive means. The diagnosis of a medically or surgically treatable lesion can obviate for the patient the often unnecessary anxiety and expense of more extensive studies.- - - - - - - - - - ranking = 1keywords = nerve (Clic here for more details about this article) |
4/5. Oculomotor anomalies in sellar and parasellar pathology.The authors report 19 cases where diplopia was the initial symptom of sellar pathology, Additionally, 5 cases with doubtful, diagnosis are discussed. Considering a series of 134 adenomata, the onset in 7 cases was intermittent diplopia with involvement of the third nerve.- - - - - - - - - - ranking = 1keywords = nerve (Clic here for more details about this article) |
5/5. Ophthalmic manifestations of multiple endocrine neoplasia, type three.We report the case of a patient with multiple endocrine neoplasia type three, which was first diagnosed by members of the department of ophthalmology. He was found to have multiple mucosal neuromata and medullary thyroid carcinoma. The ocular components of this syndrome include visible corneal nerves, conjunctival neuromas, thickened lids, anterior displacement of the cilia and a "dry eye" syndrome. The major systemic components are medullary thyroid carcinoma and pheochromocytoma. It is important that the Ophthalmologist recognize the ophthalmic manifestations of this syndrome so that early diagnosis and treatment may be possible.- - - - - - - - - - ranking = 1keywords = nerve (Clic here for more details about this article) |