Cases reported "Diabetic Foot"

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1/6. The Doppler probe for planning septofasciocutaneous advancement flaps on the plantar aspect of the foot: anatomical study and clinical applications.

    A 5-MHz Doppler probe was utilized to identify the perforating septofasciocutaneous vessels on the plantar aspect of the right and left feet of 10 healthy subjects. Each audible perforator was marked, and each foot was photographed, scanned into a personal computer, and standardized to 8 inches high by 4 inches wide. All 20 feet were then stacked together to create a composite average of all markings. Loupe aided (2.5 x magnification) dissection of a latex cast of the perforating septofasciocutaneous vessels from a fresh frozen cadaveric foot revealed similar location and distribution as the composite average described above. The Doppler probe is capable of accurately identifying the septofasciocutaneous perforating vessels, thereby, creating a vascular map of the plantar aspect of the foot useful for precise planning of advancement flap coverage for full thickness defects. Two representative case examples are presented.
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2/6. Persistent yersinia pestis antigens in ischemic tissues of a patient with septicemic plague.

    In November 2002, a couple from new mexico traveled to new york where both had fever and unilateral inguinal adenopathy. The husband was in septic shock when he sought medical care and was admitted to an intensive care unit, where he developed ischemic necrosis of his feet which later required bilateral amputation. yersinia pestis was grown from his blood. Immunohistochemical assays using anti-Y pestis antibodies demonstrated multiple bacteria and granular antigens in and around vessels of the ischemic amputation tissues obtained 20 days after initiation of antibiotics; however, no evidence of Y pestis was present in viable tissues. Immunohistochemical evidence of Y pestis inside vessels of gangrenous feet in this patient underscores the importance of adequate excision of necrotic or partially necrotic tissues because antibiotics cannot be effectively delivered to necrotic and poorly perfused tissues.
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3/6. limb salvage of infected diabetic foot ulcers with free deep inferior epigastric perforator flaps.

    Soft-tissue reconstruction of the feet in diabetic patients with angiopathy, sensorial neuropathy, and immunopathy is a complicated problem. Until the mid-1980s, chronic foot ulcers in diabetic patients were treated conservatively, because flap surgery was regarded as too risky. However, in recent years, early debridement and flap coverage have become popular reconstructive methods for diabetic foot wounds. Several flap donor sites are available, depending on the nature of the defect. The deep inferior epigastric artery perforator (DIEP) flap is a relatively new flap that developed as a modification of the transverse rectus abdominis muscle (TRAM) flap. It provides a large amount of skin and subcutaneous tissue, without the donor-site morbidity of the ordinary TRAM flap. Furthermore, using the DIEP flap avoids the loss of major vessels. In this study, we report on the successful use of the DIEP flap in four cases of diabetic foot ulceration.
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4/6. Preliminary arteriovenous fistula for free-flap reconstruction in the diabetic foot.

    We present our experience at the American University of Beirut Medical Center with two diabetic patients suffering from large necrotic and infected foot ulcers. Both patients were ambulatory at the time of presentation despite their extensive wounds and were believed to have a useful limb with adequate protective sensation worth saving. Below-knee amputation was prevented in both cases by successful soft-tissue coverage of the ulcers using microvascular composite-tissue transfer a few days after performing a preliminary arteriovenous fistula with a long vein graft loop. The flap vessels were anastomosed end-to-end to the arterial and venous limbs of the divided arteriovenous loop. This reconstructive technique of difficult diabetic wounds of the lower extremity, though in two stages, may be safer than one long procedure in a high-risk patient. It is technically easier than long interpositional vein grafts at the same time as free-flap transfer or microvascular anastomoses with small and diseased vessels. It definitely provides more chance of success as larger vessels are used to supply the flap. It permits distension of the vein graft at normotensive physiologic pressures and allows testing the arterial anastomosis as well as the venous flow before final flap transfer. Above all, it allows extreme freedom in performing tension-free anastomoses away from the infected wound.
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5/6. Endovascular obliteration of in situ saphenous vein arteriovenous fistulas during tibial bypass.

    Current methods of ligating venous branches during in situ vein tibial bypass are associated with significant wound complications, especially in diabetics. Making only proximal and distal wound incisions could avoid these wound problems. We report the use of endovascular techniques with coils and balloons guided by intraoperative arteriography and angioscopy to obliterate arteriovenous (AV) fistulas in three elderly diabetic patients undergoing tibial bypass. In all cases the proximal and distal vessels were first isolated and deemed suitable for bypass. The greater saphenous vein was prepared for the proximal and distal anastomosis, and angioscopically guided valvulotomy was performed. An introducer sheath was placed through a large proximal saphenous side branch for vascular access. With the use of fluoroscopy, AV fistulas were serially identified and cannulated with a guidewire. A guide catheter, passed over the wire into the side branch, served as the conduit through which coils and balloons were placed. Proximal and distal anastomoses were completed and arteriography performed. We were successful in obliterating AV fistulas in all three patients, but completion arteriography revealed additional AV fistulas requiring surgical ligation in two patients. Furthermore, operative time was increased by 1 1/2 to 5 hours. Two of three patients had wound infections, one at the proximal and one at the distal incision. All patients were discharged with a functioning bypass and no AV fistulas were seen on duplex scans. Endovascular obliteration of AV fistulas is feasible but is currently limited by prolonged operative time and incomplete obliteration.
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6/6. survival of a microvascular muscle flap despite the late occlusion of the inflow artery in a neuroischaemic diabetic foot.

    A microsurgical free rectus abdominis flap was connected to a popliteodistal vascular reconstruction because of a limb-threatening ischaemic ulcer in an 84 year old diabetic patient. After six months the inflow vessel occluded, but the flap stayed viable, apparently receiving its nutrition through newly developed collaterals.
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