Cases reported "Coronary Disease"

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1/397. Massive gastrointestinal hemorrhage after transoesophageal echocardiography probe insertion.

    PURPOSE: To describe a case of a massive gastric bleeding following emergency coronary artery bypass surgery associated with transoesophageal echocardiographic (TEE) examination. CLINICAL FEATURES: A 50-yr-old man was referred for an acute myocardial infarction and pulmonary edema (Killip class 3). Twelve hours after his myocardial infarction, he was still having chest pain despite an i.v. heparin infusion. coronary angiography revealed severe three-vessel disease with multifocal stenosis of the left anterior descending, circumflex and total occlusion of the right coronary artery. The patient was transferred to the operating room for emergency coronary artery bypass graft surgery. After total systemic heparinization (3 mg.kg-1) was obtained for cardiopulmonary bypass, a multiplane TEE probe was inserted without difficulty to monitor myocardial contractility during weaning from CPB. During sternal closure, the TEE probe was removed and an orogastric tube was inserted with immediate drainage of 1,200 ml red blood. Endoscopic examination demonstrated a mucosal tear near the gastro-oesophageal junction and multiple erosions were seen in the oesophagus. These lesions were successfully treated with submucosal epinephrine injections and the patient was discharged from the hospital eight days after surgery. CONCLUSION: This is a report of severe gastrointestinal hemorrhage following TEE examination in a fully heparinized patient. This incident suggest that, if the use of TEE is expected, the probe should preferably be inserted before the administration of heparin and the beginning of CPB.
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2/397. fibromuscular dysplasia involving coronary arteries--a case report.

    The authors report a young patient with fibromuscular dysplasia involving multivessels including coronary arteries. If young patients have chest pain on effort, fibromuscular dysplasia of coronary arteries must be considered. As fibromuscular dysplasia is a chronic progressive disease and some cases progress rapidly in a few months, careful follow-up and comprehensive medical management may be necessary in such patients.
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3/397. Integrated approach for revascularization in multivessel coronary artery disease and porcelain aorta.

    We report two cases in which combined beating heart revascularization of the left anterior descending artery (LAD) and percutaneous angioplasty of the non-LAD target arteries were adopted after the intraoperative detection of porcelain aorta and impossibility to complete surgical revascularization. This type of strategy preserves the benefits of surgical LAD grafting and complete revascularization and results in a simple and low-risk technical procedure in an otherwise challenging setting.
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4/397. Spontaneous recanalization of postoperative severe graft stenosis. What is the cause and prognosis of the "string sign" in the internal thoracic artery?

    A 68-year-old female with unstable angina was treated surgically. She was referred to the surgical ward by cardiologists because of a diagnosis of unstable angina with three vessel disease. On a coronary angiogram (CAG), 90% stenoses were found in the left anterior descending coronary artery (LAD), circumflex (CX), and right coronary artery (RCA). She received elective coronary artery bypass grafting (CABG), in which the left internal thoracic artery (LITA) was anastomosed to the LAD and reversed saphenous vein grafts (SVG) were made to segment 12 of the CX, and segment 4PD of the RCA, respectively. The postoperative course was uneventful, but postoperative early graftgraphy revealed distal narrowing of the LITA graft as the so-called "string sign". However, one year post surgery, the LITA string sign was not found and its patency had markedly improved on the second graftgram. It is reported that the LITA "string sign" might cause late graft occlusion. However, this LITA graft evidently enlarged the size and increased the flow of the artery in proportion to myocardial blood demand. To our knowledge, it has not been reported that an in situ LITA string sign on postoperative early graftgram has disappeared in the late phase. We hypothesize that the LITA string sign might be caused by several different factors such as flow competition, spasm, and/or technical problems. In any event, the LITA string sign does not cause graft occlusion in the late postoperative period in every case.
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5/397. pathology of bailout coronary stenting in human beings.

    OBJECTIVES: The aim of this study was to perform detailed postmortem analysis of bailout coronary stenting to gain insights into the mechanism of success or failure of the procedure. Bailout stenting is increasingly used for acute or threatened arterial closure after angioplasty. Few pathologic data from bailout stenting have been reported. methods AND RESULTS: The coronary arteries from 6 cases of bailout stenting were analyzed at autopsy. All stents were placed for extensive coronary dissection or abrupt vessel closure after balloon angioplasty. Twenty stents (11 Palmaz-Schatz and 9 Gianturco-Roubin stents) were placed in 8 coronary arteries, ranging from 1 to 5 stents per artery. After stenting, angiography showed good coronary flow in 3 of 6 cases. All patients died secondary to acute myocardial infarction. Histologically, in all cases, the stents were well opposed to the coronary artery wall, with a focally widely patent lumen by compression of the dissection plane. However, in 4 of 6 cases, there was residual dissection present in the nonstented portion of the arteries proximal, proximal to, and between stents or distal to the stented segment, resulting in focal luminal compression or obstruction. In 2 cases, bailout stenting effectively covered the dissection and prevented luminal compression. CONCLUSIONS: Bailout stenting for dissection after balloon angioplasty restores lumen patency in the stented segment. Residual dissection in nonstented segments adversely affects outcome and supports the need for continued development of new stents with increased trackability and tapering designs to more effectively treat major coronary dissections.
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6/397. A new, safer lasing technique for laser-facilitated coronary angioplasty.

    in vitro studies during cold pulsed-wave laser angioplasty have demonstrated production of gas bubbles within the target tissue, creation of shock wave and formation of multi-layer dissections accompanied by an increase in the plaque and vessel wall temperature. These processes account for certain complications of coronary lasing, including acute vessel closure, dissections, spasm, and even perforation. The traditional lasing technique in which a large number of pulses is continually emitted across the lesion, may in fact contribute to the development and acceleration of the above mentioned processes. To overcome the shortcomings we have developed a new, safe lasing technique that consists of multiple trains of a small number of pulses each. Between laser sessions the laser catheter is retracted into the guiding catheter and nitroglycerin is injected intracoronary, thus providing time for dispersion of produced gas bubbles, cooling of the target artery, and adequate coronary vasodilatation. This new technique results in a significant reduction of laser associated complications.
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7/397. Pseudo-dissection in percutaneous transluminal coronary angioplasty.

    Percutaneous transluminal coronary angioplasty (PTCA) is a well-established and effective treatment modality for significant coronary artery disease. Because it enlarges the arterial lumen by plaque disruption, minor wall dissection is not infrequent. Complex dissections are, however, uncommon but may lead to acute vessel closure with its attendant major clinical morbidity and mortality. We describe here a case of pseudo-dissection and its potential for misinterpretation and subsequent inappropriate management.
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8/397. The use of the Tracker catheter as a guidewire support device in angioplasty of angulated and tortuous circumflex coronary arteries.

    Marked angulation and tortuosity of the coronary arteries, particularly the circumflex, can limit coronary angioplasty. Despite the use of adequate guide catheter support and high performance guidewires, it is often difficult or even impossible to reach the distal segment of the target vessel with the guidewire. We describe three cases of successful complex circumflex coronary artery angioplasty where guidewire advancement through proximal angulated and tortuous anatomy was facilitated by the Tracker-18 Hi-Flow catheter after failure of conventional angioplasty hardware.
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9/397. Long-term successful coronary artery angioplasty in polycythemia vera.

    In a 65-year-old man with polycythemia vera, invalidating angina pectoris was associated with severe narrowing of the right coronary artery. After percutaneous coronary angioplasty (PTCA) the patient became symptom free and remained so for 12 months, while receiving an antiplatelet agent, a calcium antagonist and nitrate. coronary angiography repeated after a year, because of reappearance of angina, documented good patency of the treated artery and some progression of a narrowing involving another coronary vessel. This is the first reported case of long-term success of PTCA in polycythemia vera, a disease exposed to a high risk of thrombosis and, possibly, of restenosis. It is undefined whether medical treatment contributed to the anatomical and clinical results. As far as a single case can say, polycythemia vera might not represent a prohibitive background for coronary PTCA.
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10/397. Coronary pseudo-lesions induced in the left anterior descending and right coronary artery by the angioplasty guide-wire.

    New lesions appearing during coronary angioplasty may be due to a number of causes including spasm, dissection, embolisation, thrombosis and creation of a pseudo-lesion. The term "coronary pseudo-lesions" has been given to describe artefactual lesions occurring during percutaneous transluminal coronary angioplasty and induced by the angioplasty guide-wire and/or balloon as a result of straightening of the vessel's curvature. No specific treatment is required as they resolve completely on removal of the angioplasty wire. Few modern texts of interventional cardiology contain description of this important phenomenon and we suspect that they pass largely unrecognised. All angioplasty operators should become familiar with this complication as failure to do so may lead to inappropriate intervention with attendant increase in risk to the patient. We report three cases of coronary pseudo-lesion. In two cases affecting the right coronary artery and in the third the left anterior descending coronary artery. Pseudo-lesions affecting the right coronary artery have been previously reported in the literature however pseudo-lesion affecting the left anterior descending artery has not been described. The possible mechanisms of this phenomenon and its management are discussed.
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