Cases reported "Colonic Polyps"

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1/6. Polypoid arteriovenous malformation of colon mimicking inflammatory fibroid polyp.

    Arteriovenous malformation is a well-known cause of lower gastrointestinal bleeding in the elderly and usually appears as flat or elevated bright red lesions endoscopically. Here we present a 59-year-old woman with a large fungating polypoid mass in the transverse colon. Histologically, the larger vessels were located mainly in the submucosa, and smaller vessels were also observed within the mucosa. Verhoeff's elastic stain showed internal and external elastic lamina in the malformed vessels. We report an extremely rare case of a large, pedunculated, polypoid arterioveneous malformation with the first description of our complete pathological findings.
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2/6. A large inflammatory fibroid polyp of the colon treated by endoclip-assisted endoscopic polypectomy: A case report.

    Inflammatory fibroid polyp is a rare benign polypoid lesion of the gastrointestinal tract. Histologically, inflammatory fibroid polyp is characterised by an admixture of numerous small vessels, fibroblasts and oedematous connective tissue, accompanied by marked inflammatory infiltration by eosinophils. A 40-year-old man visited our hospital for the purpose of colorectal screening due to a positive faecal occult blood test. A pedunculated and reddish polyp was found endoscopically in the ascending colon. The polyp was large but was resected endoscopically without any problems. Histologically, the abnormal tissue of the polyp was located in the submucosal and mucosal layer. Proliferation of spindle cells and infiltration of inflammatory cells, such as plasma cells and eosinophils, were observed. Immunohistochemically, the spindle cells were positive for CD34, which was localised in the cytoplasm. These cells were also positive for S100 protein but were negative for c-kit and muscle markers. These findings are compatible with the histological diagnosis of inflammatory fibroid polyp. The surgical margin of the polyp was free of the tumour. Inflammatory fibroid polyp is more commonly found in the stomach or small intestine, and rarely in the colon, and therefore our case is a rare example of large and pedunculated colonic inflammatory fibroid polyp, which was treated successfully by endoscopic polypectomy.
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3/6. Small bowel infarction associated with pancreatic glucagonoma.

    An 88 year old woman presented comatose, hypothermic and hyperglycaemic. She died soon after admission and at autopsy recent small bowel infarction was found. The superior mesenteric artery was encased in a dense pancreatic mass and there was marked luminal narrowing of the vessel. histology revealed a pancreatic glucagonoma which had metastasized to colonic submucosa and serosa. glucagonoma is a rare tumour and this presentation of small bowel infarction associated with pancreatic glucagonoma would appear to be a unique event.
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4/6. Giant inflammatory polyps associated with idiopathic inflammatory bowel disease. An ultrastructural study of five cases.

    Five cases of giant inflammatory polyps associated with idiopathic inflammatory bowel disease are reported. polyps produced intestinal obstruction in three cases; consequently, surgery was performed. In a further two cases, intestinal bleeding was improved by endoscopic polypectomy. Electron microscopy showed fibroblasts, myofibroblasts, mast cells, lymphocytes, collagen fibers, capillaries, and venules. Remnants of the original mucosal epithelial cells, smooth muscle cells, and hypertrophic autonomous nerve plexuses were noted. nerve fibers were interwoven with the matrix of the polyps. mast cells were closely linked with vessels, nerves, and collagen fibers. They may have an important role in the excessive granulation, angiogenesis, and fibrotic process in giant inflammatory polyps.
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5/6. Colonic haemorrhage from solitary submucosal vessels diagnosed by lower gastrointestinal Doppler-endoscopy.

    The case of a 21-year-old woman presenting with acute gastrointestinal haemorrhage is reported. By means of Doppler-endoscopy, a solitary minute polyp located in the proximal ascending colon, which revealed arterial pulsation, was detected, and removed with the aid of forceps. The histological work-up revealed thick-walled, in part dilated, vessels located in the lamina propria and in the submucosa. Following endoscopic sclerotherapy, the patient has now been haemorrhage-free for the past 6 months. The lesion is very probably a Dieulafoy-like erosion, an entity which was previously known only in the stomach and jejunum, but which in more recent times has also been observed in the colon.
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6/6. Residual stalks of pedunculated adenomas. An underrecognized type of colonic polyp.

    Variable lengths of stalk of colonic pedunculated adenomas may be left behind at polypectomy. At follow-up endoscopy, a residual stalk is a smooth-surfaced, sessile polyp, without a distinct head, and may be difficult to remove. It may be mistaken endoscopically for either a recurrent adenoma or a polyp missed at the original procedure. Histologically, it has a coat of normal mucosa and a core of submucosa in which recanalized blood vessels, scarring, and hemosiderin deposition (consequences of thermocautery) may be seen. We present four cases illustrating the clinicopathologic problem and the pathologic appearances. One caused clinical concern because of its size and location at the site of former polypectomy. One was histologically confusing and raised the question of a vascular malformation. The third, seen at segmental colectomy after endosocopic biopsy of an adenoma, illustrates the gross appearances. The fourth contained regenerative mucosa and recanalized submucosal blood vessels.
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