1/7. Acute ischaemic colitis following intravenous cocaine use.Intestinal ischaemia is an uncommon complication of recreational cocaine abuse. We report the case of a 36-year-old male who underwent emergency surgery for acute abdomen. At laparotomy, the transverse colon appeared markedly oedematous, dilated and with subserosal haemorrhage. Segmental resection was performed and microscopic examination of the resected specimen showed focal necrosis of the mucosa with a patchy polymorphonuclear and mononuclear infiltrate. The submucosa was markedly thickened due to oedema; focal haemorrhage was observed and blood vessels were dilated but showed no structural abnormalities or thrombosis. These findings were consistent with ischaemic colitis. No risk factors for intestinal ischaemia were present but the patient stated that he had injected cocaine i.v. the day before the onset of symptoms. He was not a cocaine abuser but occasionally sniffed, smoked or injected cocaine. cocaine use should be considered in the aetiological diagnosis of intestinal ischaemia in young patients.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
2/7. cocaine abuse and coronary artery dissection.A 33-year-old man with a history of recent cocaine use presented with dissection of the left main coronary artery extending distally to involve the left anterior descending (LAD) and circumflex arteries. He required emergency four-vessel aortocoronary bypass, which was uncomplicated.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
3/7. Uterine gas vs. vessel calcification. A case report.BACKGROUND: Pelvic ultrasound plays a significant role in the diagnosis of uterine abnormalities; however, occasionally the radiologic findings may be misleading. CASE: A case of suspected uterine vessel calcification was detected on ultrasound in a patient hospitalized with pelvic inflammatory disease that was originally interpreted as uterine gas. The lack of change over serial ultrasound scans in conjunction with the patient's benign clinical course led to reassessment of the initial impression; the findings were then attributed to uterine vessel calcification. CONCLUSION: Uterine vessel calcification in a polysubstance abuser may be a manifestation of the known atherosclerotic cardiovascular complications of cocaine. Although ultrasound findings may be misleading, clinical judgment is essential to rule out clostridial endomyometritis.- - - - - - - - - - ranking = 7keywords = vessel (Clic here for more details about this article) |
4/7. Multivessel coronary thrombosis secondary to cocaine use successfully treated with multivessel primary angioplasty.cocaine use has been associated with a significant risk of myocardial ischemia and myocardial infarction (MI). The previous approach to the treatment of cocaine-induced MI focused on medical treatment with verapamil, nitroglycerine and thrombolytics. Percutaneous revascularization for the cocaine-associated MI has been reported and is the preferred treatment modality. Identification of culprit vessel in the patients presenting with acute myocardial infarction associated with cocaine use is problematic owing to the frequent presence of baseline electrocardiogram (ECG) changes. Chronic cocaine use predisposes to diffuse coronary vasculopathy and may cause systemic alteration of coagulation parameters. Multivessel coronary thrombosis presenting as myocardial infarction associated with cocaine use has not been previously reported. This study describes a case of multivessel coronary thrombosis caused by cocaine ingestion successfully treated with multivessel primary angioplasty.- - - - - - - - - - ranking = 12keywords = vessel (Clic here for more details about this article) |
5/7. Acute myocardial infarction in a young woman with antiphospholipid syndrome and occasional cocaine abuse.We describe a case of acute myocardial infarction in a 19-year-old woman reporting a history of occasional cocaine abuse with last exposure 4 days before symptom onset, otherwise at low cardiovascular risk. coronary angiography showed thrombotic occlusion of anterior descending coronary artery without atherosclerotic plaques, and complete recanalization of the vessel after anticoagulation with enoxaparine. Hypercoagulability evaluation revealed the presence of antiphospholipid antibodies. We suppose that cocaine abuse may have had a delayed effect as trigger of acute myocardial infarction. This action may be due to cocaine-induced endothelial activation and to a synergic prothrombotic activity of cocaine and antiphospholipid antibodies.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
6/7. Rapid progression of coronary artery disease in the setting of chronic cocaine abuse.Two cases of rapidly progressing coronary artery disease in the setting of chronic cocaine abuse are presented. One patient, a 39-year-old female, developed a significant left anterior descending artery (LAD) stenosis over a 10-month period and suffered an acute myocardial infarction (MI). The second patient, a 35-year-old male, developed significant progression of three vessel coronary artery disease (CAD) over 16 months and also suffered an MI temporally related to cocaine use. Though recent cocaine use is typically considered a risk factor for acute cardiac events, chronic use may contribute to the development or rapid progression of coronary artery disease in young patients.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |
7/7. cocaine-induced thrombosis of common iliac and popliteal arteries.cocaine-induced thrombosis has been reported in the literature; however, its mechanism is not fully understood. Most cases are of small caliber vessels, such as the coronaries and cerebral vasculature. We report a case of a 36-year-old man with signs and symptoms of acute arterial insufficiency in his right lower extremity. At angiography, the right common iliac artery and the popliteal artery were occluded. The patient was successfully treated with thrombolytic therapy. cocaine-induced thrombosis should be suspected in a patient with history of cocaine abuse who presents with acute arterial insufficiency in an extremity, without an identifiable source.- - - - - - - - - - ranking = 1keywords = vessel (Clic here for more details about this article) |